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Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

Cell, 2012-02, Vol.148 (4), p.727-738

2012

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The Mammalian Proteasome Activator PA28 Forms an Asymmetric α4β3 Complex

Structure (London), 2017-10, Vol.25 (10), p.1473-1480.e3

2017

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Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914

Structure (London), 2015-02, Vol.23 (2), p.407-417

2015

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A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome

Nature communications, 2016-03, Vol.7 (1), p.10900-10, Article 10900

2016

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A Nut for Every Bolt: Subunit-Selective Inhibitors of the Immunoproteasome and Their Therapeutic Potential

Cells (Basel, Switzerland), 2021-07, Vol.10 (8), p.1929

2021

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Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

Chembiochem : a European journal of chemical biology, 2022-12, Vol.23 (23), p.e202200341-n/a

Huber, Eva M.

2022

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Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products

Angewandte Chemie (International ed.), 2014-02, Vol.53 (8), p.2221-2224

International ed. in English, 2014

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DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex

Structure (London), 2012-10, Vol.20 (10), p.1757-1768

2012

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The 19S Cap Puzzle: A New Jigsaw Piece

Structure (London), 2012-03, Vol.20 (3), p.387-388

2012

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Defective immuno- and thymoproteasome assembly causes severe immunodeficiency

Scientific reports, 2018-04, Vol.8 (1), p.5975-18, Article 5975

2018

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The CCAAT-binding complex (CBC) in Aspergillus species

Biochimica et biophysica acta. Gene regulatory mechanisms, 2017-05, Vol.1860 (5), p.560-570

2017

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The 20S immunoproteasome and constitutive proteasome bind with the same affinity to PA28αβ and equally degrade FAT10

Molecular immunology, 2019-09, Vol.113, p.22-30

2019

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Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases

Angewandte Chemie International Edition, 2018-10, Vol.57 (44), p.14624-14629

International ed. in English, 2018

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Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine

Angewandte Chemie (International ed.), 2015-12, Vol.54 (52), p.15888-15891

International ed. in English, 2015

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Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX

Structure (London), 2022-07, Vol.30 (7), p.934-946.e4

2022

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Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin

Angewandte Chemie International Edition, 2021-06, Vol.60 (25), p.14188-14194

International ed. in English, 2021

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The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2

Molecular cell, 2019-04, Vol.74 (1), p.73-87.e8

2019

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Strukturelle und mechanistische Einblicke in die Bildung der C‐S‐Bindungen in Gliotoxin

Angewandte Chemie, 2021-06, Vol.133 (25), p.14307-14314

2021

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A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments

Structure (London), 2023-05, Vol.31 (5), p.573-583.e5

2023

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Structure-Based Design of β1i or β5i Specific Inhibitors of Human Immunoproteasomes

Journal of medicinal chemistry, 2014-07, Vol.57 (14), p.6197-6209

2014

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A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i

The EMBO journal, 2016-12, Vol.35 (23), p.2602-2613

2016

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A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit [beta]5i

The EMBO journal, 2016-12, Vol.35 (23), p.2602

2016

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Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors

Journal of the American Chemical Society, 2015-06, Vol.137 (24), p.7835-7842

2015

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Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1626-1642

2019

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Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome

Chembiochem : a European journal of chemical biology, 2017-03, Vol.18 (6), p.523-526

2017

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Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

The Mammalian Proteasome Activator PA28 Forms an Asymmetric α4β3 Complex

Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914

A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome

A Nut for Every Bolt: Subunit-Selective Inhibitors of the Immunoproteasome and Their Therapeutic Potential

Epipolythiodioxopiperazine‐Based Natural Products: Building Blocks, Biosynthesis and Biological Activities

Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products

DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex

The 19S Cap Puzzle: A New Jigsaw Piece

Defective immuno- and thymoproteasome assembly causes severe immunodeficiency

The CCAAT-binding complex (CBC) in Aspergillus species

The 20S immunoproteasome and constitutive proteasome bind with the same affinity to PA28αβ and equally degrade FAT10

Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases

Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine

Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX

Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin

The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2

Strukturelle und mechanistische Einblicke in die Bildung der C‐S‐Bindungen in Gliotoxin

A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments

Structure-Based Design of β1i or β5i Specific Inhibitors of Human Immunoproteasomes

A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i

A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit [beta]5i

Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors

Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits

Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome

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