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MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II

Molecules (Basel, Switzerland), 2023-07, Vol.28 (14), p.5598

2023

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Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy

Molecules (Basel, Switzerland), 2022-08, Vol.27 (17), p.5561

2022

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A novel HSF1 activator ameliorates non‐alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation

British journal of pharmacology, 2022-04, Vol.179 (7), p.1411-1432

2022

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Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas

World journal of gastroenterology : WJG, 2015-03, Vol.21 (9), p.2629-2637

2015

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Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G‑Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3875-3891

2015

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Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2013-05, Vol.63, p.299-312

2013

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Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease

Biochimica et biophysica acta, 2014-09, Vol.1840 (9), p.2886-2903

2014

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Sensitized near infrared emission through supramolecular d → f energy transfer within an ionic Ru(ii)-Er(iii) pair

Dalton transactions : an international journal of inorganic chemistry, 2018, Vol.47 (6), p.2073-2078

2018

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Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase

European journal of medicinal chemistry, 2009-06, Vol.44 (6), p.2523-2532

2009

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Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3414-3417

2009

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Solid-phase ripening of hexanitrostilbene (HNS) nanoparticles: Effects of temperature and solvent vapour

Energetic materials frontiers, 2022-12, Vol.3 (4), p.240-247

2022

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Heat-induced solid-state polymorphic transition of 4,4′,5,5′- tetranitro-1H,1′H-[2,2′-biimidazole]-1,1′-diamine (DATNBI)

Energetic materials frontiers, 2022-06, Vol.3 (2), p.74-83

2022

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Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.1004-1009

2011

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Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation

Bioorganic & medicinal chemistry, 2018-09, Vol.26 (16), p.4693-4705

2018

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Biological Function and Medicinal Research Significance of G-Quadruplex Interactive Proteins

Current topics in medicinal chemistry, 2015-01, Vol.15 (19), p.1971-1987

2015

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Syntheses And Evaluation Of Asymmetric Curcumin Analogues As Potential Multifunctional Agents For The Treatment Of Alzheimer's Disease

Current Alzheimer research, 2015-01, Vol.12 (5), p.403-414

2015

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Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9752-9772

2020

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Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c‑MYC Transcription Repressors Targeting the Promoter G‑Quadruplex

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.12675-12700

2022

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Three-Component Catalytic Carboxygenation of Activated Alkenes Enabled by Bimetallic Rh(III)/Cu(II) Catalysis

Organic letters, 2017-11, Vol.19 (21), p.5868-5871

2017

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Synthesis of Benzofused N‑Heterocycles via Rh(III)-Catalyzed Direct Benzannulation with 1,3-Dienes

ACS catalysis, 2019-01, Vol.9 (1), p.556-564

2019

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Derivatives of oxoisoaporphine alkaloids: A novel class of selective acetylcholinesterase inhibitors

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (13), p.3765-3768

2007

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Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer

Journal of medicinal chemistry, 2023-06, Vol.66 (11), p.7387-7404

2023

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Discovery of a Novel G‑Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12346-12366

2022

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Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

Journal of medicinal chemistry, 2019-03, Vol.62 (6), p.3147-3162

2019

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Synthesis and antimultidrug resistance evaluation of icariin and its derivatives

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4237-4240

2009

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MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy

A novel HSF1 activator ameliorates non‐alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation

Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G‑Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

Synthesis and characterization of 1H-phenanthro[9,10-d]imidazole derivatives as multifunctional agents for treatment of Alzheimer's disease

Sensitized near infrared emission through supramolecular d → f energy transfer within an ionic Ru(ii)-Er(iii) pair

Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

Solid-phase ripening of hexanitrostilbene (HNS) nanoparticles: Effects of temperature and solvent vapour

Heat-induced solid-state polymorphic transition of 4,4′,5,5′- tetranitro-1H,1′H-[2,2′-biimidazole]-1,1′-diamine (DATNBI)

Pharmacophore-based discovery of triaryl-substituted imidazole as new telomeric G-quadruplex ligand

Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation

Biological Function and Medicinal Research Significance of G-Quadruplex Interactive Proteins

Syntheses And Evaluation Of Asymmetric Curcumin Analogues As Potential Multifunctional Agents For The Treatment Of Alzheimer's Disease

Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c‑MYC Transcription Repressors Targeting the Promoter G‑Quadruplex

Three-Component Catalytic Carboxygenation of Activated Alkenes Enabled by Bimetallic Rh(III)/Cu(II) Catalysis

Synthesis of Benzofused N‑Heterocycles via Rh(III)-Catalyzed Direct Benzannulation with 1,3-Dienes

Derivatives of oxoisoaporphine alkaloids: A novel class of selective acetylcholinesterase inhibitors

Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer

Discovery of a Novel G‑Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

Synthesis and antimultidrug resistance evaluation of icariin and its derivatives

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