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Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations

Chemical biology & drug design, 2017-04, Vol.89 (4), p.585-598

2017

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Severe congenital hemolytic anemia caused by a novel compound heterozygous PKLR gene mutation in a Chinese boy

Chinese medical journal, 2019-01, Vol.132 (1), p.92-95

2019

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Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo

Molecular pharmacology, 2019-11, Vol.96 (5), p.589-599

2019

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Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1‑(4-((1H‑Pyrazolo[3,4‑d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5‑(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8293-8305

2016

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From Lead to Drug Candidate: Optimization of 3‑(Phenylethynyl)‑1H‑pyrazolo[3,4‑d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9788-9805

2016

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Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants

European journal of medicinal chemistry, 2018-01, Vol.143, p.1148-1164

2018

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Different oxidation routes for lattice oxygen recovery of double-perovskite type oxides LaSrFeCoO6 as oxygen carriers for chemical looping steam methane reforming

Journal of energy chemistry, 2017-05, Vol.26 (3), p.501-509

2017

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From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1 H -pyrazolo[3,4- d ]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9788-9805

2016

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Effect of early nutrition on intestine development of intrauterine growth retardation in rats and its correlation to leptin

World journal of gastroenterology : WJG, 2005-07, Vol.11 (28), p.4419

2005

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AKT-modified autologous intracoronary mesenchymal stem cells prevent remodeling and repair in swine infarcted myocardium

Chinese medical journal, 2010-07, Vol.123 (13), p.1702-1708

2010

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Recurrent Neural Network for Predicting Transcription Factor Binding Sites

Scientific reports, 2018-10, Vol.8 (1), p.15270-10, Article 15270

2018

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Electronic structures and enhanced photocatalytic properties of blue phosphorene/BSe van der Waals heterostructures

Journal of materials chemistry. A, Materials for energy and sustainability, 2018, Vol.6 (19), p.8923-8929

2018

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Domino-like multi-emissions across red and near infrared from solid-state 2-/2,6-aryl substituted BODIPY dyes

Nature communications, 2018-07, Vol.9 (1), p.2688-9, Article 2688

2018

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Metabolic engineering of Escherichia coli for microbial production of L‐methionine

Biotechnology and bioengineering, 2017-04, Vol.114 (4), p.843-851

2017

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Cooperative Shielding of Bi-Electrodes via In Situ Amorphous Electrode–Electrolyte Interphases for Practical High-Energy Lithium-Metal Batteries

Journal of the American Chemical Society, 2021-10, Vol.143 (40), p.16768-16776

2021

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Serum MMP-7 in the Diagnosis of Biliary Atresia

Pediatrics (Evanston), 2019-11, Vol.144 (5)

2019

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Spatial and seasonal variations of PM2.5 mass and species during 2010 in Xi'an, China

The Science of the total environment, 2015-03, Vol.508, p.477-487

2015

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Light absorption properties of brown carbon over the southeastern Tibetan Plateau

The Science of the total environment, 2018-06, Vol.625, p.246-251

2018

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Design and Optimization of Amplifying Mechanism in Gas-Liquid Thermoelectric Power Device

Journal of physics. Conference series, 2022-10, Vol.2355 (1), p.12033

2022

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The nasal microbiome of predicting bronchopulmonary dysplasia in preterm infants

Scientific reports, 2022-05, Vol.12 (1), p.7727-7727, Article 7727

2022

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Spectral dependence of aerosol light absorption at an urban and a remote site over the Tibetan Plateau

The Science of the total environment, 2017-07, Vol.590-591, p.14-21

2017

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Gut microbial profile in biliary atresia: a case‐control study

Journal of gastroenterology and hepatology, 2020-02, Vol.35 (2), p.334-342

2020

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Safety, tolerability, pharmacokinetic, pharmacodynamic and immunogenicity profiles of Exendin‐4‐IgG4‐Fc in healthy subjects: A phase 1, single‐centre, randomized, double‐blind, dose escalation study

Diabetes, obesity & metabolism, 2024-04, Vol.26 (4), p.1395-1406

2024

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iCRBP-LKHA: Large convolutional kernel and hybrid channel-spatial attention for identifying circRNA-RBP interaction sites

PLoS computational biology, 2024-08, Vol.20 (8), p.e1012399

2024

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iCircDA-NEAE: Accelerated attribute network embedding and dynamic convolutional autoencoder for circRNA-disease associations prediction

PLoS computational biology, 2023-08, Vol.19 (8), p.e1011344

2023

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Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations

Severe congenital hemolytic anemia caused by a novel compound heterozygous PKLR gene mutation in a Chinese boy

Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo

Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1‑(4-((1H‑Pyrazolo[3,4‑d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5‑(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model

From Lead to Drug Candidate: Optimization of 3‑(Phenylethynyl)‑1H‑pyrazolo[3,4‑d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer

Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants

Different oxidation routes for lattice oxygen recovery of double-perovskite type oxides LaSrFeCoO6 as oxygen carriers for chemical looping steam methane reforming

From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1 H -pyrazolo[3,4- d ]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer

Effect of early nutrition on intestine development of intrauterine growth retardation in rats and its correlation to leptin

AKT-modified autologous intracoronary mesenchymal stem cells prevent remodeling and repair in swine infarcted myocardium

Recurrent Neural Network for Predicting Transcription Factor Binding Sites

Electronic structures and enhanced photocatalytic properties of blue phosphorene/BSe van der Waals heterostructures

Domino-like multi-emissions across red and near infrared from solid-state 2-/2,6-aryl substituted BODIPY dyes

Metabolic engineering of Escherichia coli for microbial production of L‐methionine

Cooperative Shielding of Bi-Electrodes via In Situ Amorphous Electrode–Electrolyte Interphases for Practical High-Energy Lithium-Metal Batteries

Serum MMP-7 in the Diagnosis of Biliary Atresia

Spatial and seasonal variations of PM2.5 mass and species during 2010 in Xi'an, China

Light absorption properties of brown carbon over the southeastern Tibetan Plateau

Design and Optimization of Amplifying Mechanism in Gas-Liquid Thermoelectric Power Device

The nasal microbiome of predicting bronchopulmonary dysplasia in preterm infants

Spectral dependence of aerosol light absorption at an urban and a remote site over the Tibetan Plateau

Gut microbial profile in biliary atresia: a case‐control study

Safety, tolerability, pharmacokinetic, pharmacodynamic and immunogenicity profiles of Exendin‐4‐IgG4‐Fc in healthy subjects: A phase 1, single‐centre, randomized, double‐blind, dose escalation study

iCRBP-LKHA: Large convolutional kernel and hybrid channel-spatial attention for identifying circRNA-RBP interaction sites

iCircDA-NEAE: Accelerated attribute network embedding and dynamic convolutional autoencoder for circRNA-disease associations prediction

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