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Design, synthesis and pharmacological evaluation of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives as potential antitumor agents

European journal of medicinal chemistry, 2018-09, Vol.157, p.139-150

2018

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Synthesis and Biological Evaluation of Novel 2-Amino-1,4-Naphthoquinone Amide-Oxime Derivatives as Potent IDO1/STAT3 Dual Inhibitors with Prospective Antitumor Effects

Molecules (Basel, Switzerland), 2023-08, Vol.28 (16), p.6135

2023

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16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, induces apoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress

Phytomedicine (Stuttgart), 2018-03, Vol.41, p.33-44

2018

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Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities

PloS one, 2017-04, Vol.12 (4), p.e0175502-e0175502

2017

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4-Methylumbelliferones Analogues as Anticancer Agents: Synthesis and in Cell Pharmacological Studies

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (4), p.576-589

2017

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Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA

European journal of medicinal chemistry, 2021-01, Vol.210, p.112951, Article 112951

2021

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Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance

European journal of medicinal chemistry, 2024-01, Vol.263, p.115937-115937, Article 115937

2024

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Targeted isolation, structural characterization and cytotoxicity evaluation of isoquinoline alkaloids from Corydalis saxicola

Journal of molecular structure, 2023-12, Vol.1293, p.136240, Article 136240

2023

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Discovery of dehydroabietic acid sulfonamide based derivatives as selective matrix metalloproteinases inactivators that inhibit cell migration and proliferation

European journal of medicinal chemistry, 2017-09, Vol.138, p.979-992

2017

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Discovery of 2H-chromone-4-one based sulfonamide derivatives as potent retinoic acid receptor-related orphan receptor γt inverse agonists

European journal of medicinal chemistry, 2022-02, Vol.229, p.114065, Article 114065

2022

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Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents

European journal of medicinal chemistry, 2015-05, Vol.95, p.435-452

2015

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Selagintamarlin A: A Selaginellin Analogue Possessing a 1H‑2-Benzopyran Core from Selaginella tamariscina

ACS omega, 2017-05, Vol.2 (5), p.2178-2183

2017

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Synthesis and pharmacological evaluation of polyamine-diarylidenyl piperidone derivatives as potent antitumor agents

Monatshefte für Chemie, 2024-07, Vol.155 (7), p.747-753

2024

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Cytotoxic triterpenoid saponins from Lysimachia foenum-graecum

Phytochemistry (Oxford), 2017-04, Vol.136, p.165-174

2017

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Discovery of novel sulfonamide chromone-oxime derivatives as potent indoleamine 2,3-dioxygenase 1 inhibitors

European journal of medicinal chemistry, 2023-06, Vol.254, p.115349-115349, Article 115349

2023

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NF-κB inhibitory and cytotoxic activities of hexacyclic triterpene acid constituents from Glechoma longituba

Phytomedicine (Stuttgart), 2019-10, Vol.63, p.153037-153037, Article 153037

2019

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Chemical composition, in vitro anti-tumor activities and related mechanisms of the essential oil from the roots of Potentilla discolor

Industrial crops and products, 2018-03, Vol.113, p.19-27

2018

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A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway

European journal of pharmacology, 2018-11, Vol.838, p.157-169

2018

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Ursolic acid-piperazine-dithiocarbamate ruthenium(II) polypyridyl complexes induced necroptosis in MGC-803 cells

Metallomics, 2022-10, Vol.14 (10)

2022

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Design, docking optimization, and evaluation of biotin-PEG4-1,8-naphthalimide as a potent and safe antitumor agent with dual targeting of ferroptosis and DNA

RSC medicinal chemistry, 2024-05, Vol.15 (5), p.164-1651

2024

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Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents

European journal of medicinal chemistry, 2014-10, Vol.86, p.175-188

2014

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Discovery of antitumor ursolic acid long-chain diamine derivatives as potent inhibitors of NF-κB

Bioorganic chemistry, 2018-09, Vol.79, p.265-276

2018

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Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance

Bioorganic chemistry, 2023-02, Vol.131, p.106323, Article 106323

2023

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Cyclic pentapeptide type compounds from Clerodendrum japonicum (Thunb.) Sweet

Tetrahedron letters, 2018-09, Vol.59 (38), p.3481-3484

2018

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Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (2), p.501-507

2014

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Design, synthesis and pharmacological evaluation of new 3-(1H-benzimidazol-2-yl)quinolin-2(1H)-one derivatives as potential antitumor agents

Synthesis and Biological Evaluation of Novel 2-Amino-1,4-Naphthoquinone Amide-Oxime Derivatives as Potent IDO1/STAT3 Dual Inhibitors with Prospective Antitumor Effects

16-O-caffeoyl-16-hydroxylhexadecanoic acid, a medicinal plant-derived phenylpropanoid, induces apoptosis in human hepatocarcinoma cells through ROS-dependent endoplasmic reticulum stress

Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities

4-Methylumbelliferones Analogues as Anticancer Agents: Synthesis and in Cell Pharmacological Studies

Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA

Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance

Targeted isolation, structural characterization and cytotoxicity evaluation of isoquinoline alkaloids from Corydalis saxicola

Discovery of dehydroabietic acid sulfonamide based derivatives as selective matrix metalloproteinases inactivators that inhibit cell migration and proliferation

Discovery of 2H-chromone-4-one based sulfonamide derivatives as potent retinoic acid receptor-related orphan receptor γt inverse agonists

Design, synthesis and in vitro evaluation of novel ursolic acid derivatives as potential anticancer agents

Selagintamarlin A: A Selaginellin Analogue Possessing a 1H‑2-Benzopyran Core from Selaginella tamariscina

Synthesis and pharmacological evaluation of polyamine-diarylidenyl piperidone derivatives as potent antitumor agents

Cytotoxic triterpenoid saponins from Lysimachia foenum-graecum

Discovery of novel sulfonamide chromone-oxime derivatives as potent indoleamine 2,3-dioxygenase 1 inhibitors

NF-κB inhibitory and cytotoxic activities of hexacyclic triterpene acid constituents from Glechoma longituba

Chemical composition, in vitro anti-tumor activities and related mechanisms of the essential oil from the roots of Potentilla discolor

A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway

Ursolic acid-piperazine-dithiocarbamate ruthenium(II) polypyridyl complexes induced necroptosis in MGC-803 cells

Design, docking optimization, and evaluation of biotin-PEG4-1,8-naphthalimide as a potent and safe antitumor agent with dual targeting of ferroptosis and DNA

Synthesis and biological evaluation of novel aniline-derived asiatic acid derivatives as potential anticancer agents

Discovery of antitumor ursolic acid long-chain diamine derivatives as potent inhibitors of NF-κB

Discovery of two biotin-PEG4‑diarylidenyl piperidone prodrugs as potent antitumor agents with good efficacy, limited toxicity, and low resistance

Cyclic pentapeptide type compounds from Clerodendrum japonicum (Thunb.) Sweet

Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates

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