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NF-κB regulation: lessons from structures

Immunological reviews, 2012-03, Vol.246 (1), p.36-58

2012

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A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation

PLoS biology, 2013-06, Vol.11 (6), p.e1001581

2013

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p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.15946-15951

2014

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PRMT5 dimethylates R30 of the p65 subunit to activate NF-[kappa]B

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13516

2013

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NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes

EMBO reports, 2009-02, Vol.10 (2), p.152-159

2009

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Crystal structure of NF-κB (p50)2 complexed to a high-affinity RNA aptamer

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (16), p.9268-9273

2003

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PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13516-13521

2013

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Structural Basis for the Activation of IKK1/α

Cell reports (Cambridge), 2016-11, Vol.17 (8), p.1907-1914

2016

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Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit

Biochemistry (Easton), 2018-05, Vol.57 (20), p.2943-2957

2018

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DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated

The Journal of biological chemistry, 2017-11, Vol.292 (46), p.18821-18830

2017

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Role of lysine methylation of NF-?B in differential gene regulation

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13510

2013

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A Structural Basis for Selective Dimerization by NF-κB RelB

Journal of molecular biology, 2013-06, Vol.425 (11), p.1934-1945

2013

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Role of lysine methylation of NF-κB in differential gene regulation

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13510-13515

2013

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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Journal of visualized experiments, 2018-11 (141)

2018

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The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

Cell, 1998-12, Vol.95 (6), p.759-770

1998

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The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50

Science signaling, 2011-02, Vol.4 (161), p.ra11

2011

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Euonymus alatus and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways

American journal of translational research, 2019-01, Vol.11 (1), p.106-119

2019

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The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs

Nucleic acids research, 2011-11, Vol.39 (21), p.9413

2011

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X-ray Crystal Structure of an IκBβ·NF-κB p65 Homodimer Complex

The Journal of biological chemistry, 2003-06, Vol.278 (25), p.23094-23100

2003

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NF-κB RelB Forms an Intertwined Homodimer

Structure (London), 2005-09, Vol.13 (9), p.1365-1373

2005

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Probing Kinase Activation and Substrate Specificity with an Engineered Monomeric IKK2

Biochemistry (Easton), 2014-04, Vol.53 (12), p.2064-2073

2014

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Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA

Nature (London), 1998-01, Vol.391 (6665), p.410-413

1998

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X-ray Structure of a NF-κB p50/RelB/DNA Complex Reveals Assembly of Multiple Dimers on Tandem κB Sites

Journal of molecular biology, 2007-10, Vol.373 (3), p.723-734

2007

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The X-ray Crystal Structure of the NF-κB p50·p65 Heterodimer Bound to the Interferon β-κB Site

The Journal of biological chemistry, 2002-07, Vol.277 (27), p.24694-24700

2002

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Effects of Coriaria Sinica Maxim's extract on microcirculation and oxidative stress of wounds in rats with deep second-degree burn

Zhongguo ying yong sheng li xue za zhi, 2018-01, Vol.34 (1), p.50

2018

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NF-κB regulation: lessons from structures

A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation

PRMT5 dimethylates R30 of the p65 subunit to activate NF-[kappa]B

NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes

Crystal structure of NF-κB (p50)2 complexed to a high-affinity RNA aptamer

PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB

Structural Basis for the Activation of IKK1/α

Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit

DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated

Role of lysine methylation of NF-?B in differential gene regulation

A Structural Basis for Selective Dimerization by NF-κB RelB

Role of lysine methylation of NF-κB in differential gene regulation

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50

Euonymus alatus and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways

The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs

X-ray Crystal Structure of an IκBβ·NF-κB p65 Homodimer Complex

NF-κB RelB Forms an Intertwined Homodimer

Probing Kinase Activation and Substrate Specificity with an Engineered Monomeric IKK2

Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA

X-ray Structure of a NF-κB p50/RelB/DNA Complex Reveals Assembly of Multiple Dimers on Tandem κB Sites

The X-ray Crystal Structure of the NF-κB p50·p65 Heterodimer Bound to the Interferon β-κB Site

Effects of Coriaria Sinica Maxim's extract on microcirculation and oxidative stress of wounds in rats with deep second-degree burn

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