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Epigenetic regulation by the menin pathway

Endocrine-related cancer, 2017-10, Vol.24 (10), p.T147-T159

2017

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Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Nature (London), 2015-09, Vol.525 (7568), p.206-211

2015

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The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

Nature (London), 2012-02, Vol.482 (7386), p.542-546

2012

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Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (2), p.401-411

2017

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Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

Cancer cell, 2010-10, Vol.18 (4), p.329-340

2010

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In search of tumor suppressing functions of menin

Molecular and cellular endocrinology, 2007-02, Vol.265-266, p.34-41

2007

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CAR T cells targeting CD13 controllably induce eradication of acute myeloid leukemia with a single domain antibody switch

Leukemia, 2021-11, Vol.35 (11), p.3309-3313

2021

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Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB

American journal of physiology: endocrinology and metabolism, 2017-08, Vol.313 (2), p.E148-E166

2017

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Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8), p.2650-2658

2013

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Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

Diabetes (New York, N.Y.), 2018-07, Vol.67 (7), p.1345-1355

2018

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Roux-en-Y gastric bypass enhances insulin secretion in type 2 diabetes via FXR-mediated TRPA1 expression

Molecular metabolism (Germany), 2019-11, Vol.29, p.1-11

2019

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Regulation of Cyclin B2 Expression and Cell Cycle G2/M Transition by Menin

The Journal of biological chemistry, 2010-06, Vol.285 (24), p.18291-18300

2010

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Structural Modeling and in Silico Screening of Potential Small-Molecule Allosteric Agonists of a Glucagon-like Peptide 1 Receptor

ACS omega, 2019-01, Vol.4 (1), p.961-970

2019

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Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (3), p.749-754

2005

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Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective

Current molecular medicine, 2008-12, Vol.8 (8), p.805-815

2008

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Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation

EMBO molecular medicine, 2021-05, Vol.13 (5), p.e13524-n/a

2021

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The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia

Haematologica (Roma), 2013-06, Vol.98 (6), p.918-927

2013

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Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20358-20363

2010

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Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw

PloS one, 2012-09, Vol.7 (9), p.e45380-e45380

2012

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Menin localization in cell membrane compartment

Cancer biology & therapy, 2016-01, Vol.17 (1), p.114-122

2016

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Targeting ROS: Selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound

Cancer biology & therapy, 2007-05, Vol.6 (5), p.646-647

2007

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The Tumor Suppressor Menin Regulates Hematopoiesis and Myeloid Transformation by Influencing Hox Gene Expression

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (4), p.1018-1023

2006

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FOXO family in regulating cancer and metabolism

Seminars in cancer biology, 2018-06, Vol.50, p.32-41

2018

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Menin associates with FANCD2, a protein involved in repair of DNA damage

Cancer research (Chicago, Ill.), 2003-07, Vol.63 (14), p.4204-4210

2003

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Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells

Cancer research (Chicago, Ill.), 2006-06, Vol.66 (11), p.5707-5715

2006

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Epigenetic regulation by the menin pathway

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase

Nuclear Cyclin D1/CDK4 Kinase Regulates CUL4 Expression and Triggers Neoplastic Growth via Activation of the PRMT5 Methyltransferase

In search of tumor suppressing functions of menin

CAR T cells targeting CD13 controllably induce eradication of acute myeloid leukemia with a single domain antibody switch

Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB

Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome

Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

Roux-en-Y gastric bypass enhances insulin secretion in type 2 diabetes via FXR-mediated TRPA1 expression

Regulation of Cyclin B2 Expression and Cell Cycle G2/M Transition by Menin

Structural Modeling and in Silico Screening of Potential Small-Molecule Allosteric Agonists of a Glucagon-like Peptide 1 Receptor

Menin and MLL Cooperatively Regulate Expression of Cyclin-Dependent Kinase Inhibitors

Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective

Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation

The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia

Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene

Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw

Menin localization in cell membrane compartment

Targeting ROS: Selective killing of cancer cells by a cruciferous vegetable derived pro-oxidant compound

The Tumor Suppressor Menin Regulates Hematopoiesis and Myeloid Transformation by Influencing Hox Gene Expression

FOXO family in regulating cancer and metabolism

Menin associates with FANCD2, a protein involved in repair of DNA damage

Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells

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