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Towards the next generation of biomedicines by site-selective conjugation

Chemical Society reviews, 2016-03, Vol.45 (6), p.1691-1719

2016

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Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Angewandte Chemie (International ed.), 2015-11, Vol.54 (45), p.13198-13203

International ed. in English, 2015

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Phase 1 study to evaluate safety, tolerability and pharmacokinetics of a novel intra-tympanic administered thiosulfate to prevent cisplatin-induced hearing loss in cancer patients

Investigational new drugs, 2020-10, Vol.38 (5), p.1463-1471

2020

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Defined Conjugation of Glycans to the Lysines of CRM197 Guided by their Reactivity Mapping

Chembiochem : a European journal of chemical biology, 2014-04, Vol.15 (6), p.836-843

2014

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Synthesis of a well-defined glycoconjugate vaccine by a tyrosine-selective conjugation strategy

Chemical science (Cambridge), 2013-01, Vol.4 (10), p.3827

2013

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Tyrosine-Directed Conjugation of Large Glycans to Proteins via Copper-Free Click Chemistry

Bioconjugate chemistry, 2014-12, Vol.25 (12), p.2105-2111

2014

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Structure–Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4749-4770

2015

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Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

Current topics in medicinal chemistry, 2016-07, Vol.16 (16), p.1792-1818

2016

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Frontispiece: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Angewandte Chemie (International ed.), 2015-11, Vol.54 (45), p.n/a

International ed. in English, 2015

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An item orientated recommendation algorithm from the multi-view perspective

Neurocomputing (Amsterdam), 2017-12, Vol.269, p.261-272

2017

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Item orientated recommendation by multi-view intact space learning with overlapping

Knowledge-based systems, 2019-01, Vol.164, p.358-370

2019

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Deciphering the structure–immunogenicity relationship of anti- Candida glycoconjugate vaccines

Chemical science (Cambridge), 2014-09, Vol.5 (11), p.4302-4311

2014

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Useful Enantioselective Bicyclization Reactions Using an N-Protonated Chiral Oxazaborolidine as Catalyst

Organic letters, 2003-10, Vol.5 (21), p.3979-3982

2003

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Pharmacokinetics and tissue distribution of neurotrophin 3 after intracochlear delivery

Journal of controlled release, 2019-04, Vol.299, p.53-63

2019

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Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide

Bioconjugate chemistry, 2015-08, Vol.26 (8), p.1839-1849

2015

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Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation

ACS chemical biology, 2015-07, Vol.10 (7), p.1737-1746

2015

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Simple, Catalytic Enantioselective Syntheses of Estrone and Desogestrel

Journal of the American Chemical Society, 2004-05, Vol.126 (19), p.5984-5986

2004

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The First In(OTf)3-Catalyzed Conversion of Kinetically Formed Homoallylic Alcohols into the Thermodynamically Preferred Regioisomers: Application to the Synthesis of 22α-Sterols

Angewandte Chemie (International ed.), 2001-08, Vol.40 (15), p.2921-2922

2001

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Diverse Cyclization Catalyzed by In(OTf)3 for the Convergent Assembly of Substituted Tetrahydrofurans and Tetrahydropyrans

Organic letters, 2001-08, Vol.3 (17), p.2669-2672

2001

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New hypotheses about the structure-function of proprotein convertase subtilisin/kexin type 9: Analysis of the epidermal growth factor-like repeat A docking site using WaterMap

Proteins, structure, function, and bioinformatics, 2010-09, Vol.78 (12), p.2571-2586

2010

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Frontispiz: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Angewandte Chemie, 2015-11, Vol.127 (45), p.n/a

2015

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Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Angewandte Chemie, 2015-11, Vol.127 (45), p.13396-13401

2015

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Stereocontrolled Synthesis of Linear 22R-Homoallylic Sterols via a Triflic Acid-Catalyzed 2-Oxonia Cope Rearrangement

Organic letters, 2002-07, Vol.4 (14), p.2389-2391

2002

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Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors

ACS medicinal chemistry letters, 2013-12, Vol.4 (12), p.1203-1207

2013

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Synthetic Studies toward Anisatin: A Formal Synthesis of (±)-8-Deoxyanisatin

Organic letters, 2001-01, Vol.3 (2), p.279-281

2001

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Towards the next generation of biomedicines by site-selective conjugation

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Phase 1 study to evaluate safety, tolerability and pharmacokinetics of a novel intra-tympanic administered thiosulfate to prevent cisplatin-induced hearing loss in cancer patients

Defined Conjugation of Glycans to the Lysines of CRM197 Guided by their Reactivity Mapping

Synthesis of a well-defined glycoconjugate vaccine by a tyrosine-selective conjugation strategy

Tyrosine-Directed Conjugation of Large Glycans to Proteins via Copper-Free Click Chemistry

Structure–Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors

Implications of Dynamic Occupancy, Binding Kinetics, and Channel Gating Kinetics for hERG Blocker Safety Assessment and Mitigation

Frontispiece: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

An item orientated recommendation algorithm from the multi-view perspective

Item orientated recommendation by multi-view intact space learning with overlapping

Deciphering the structure–immunogenicity relationship of anti- Candida glycoconjugate vaccines

Useful Enantioselective Bicyclization Reactions Using an N-Protonated Chiral Oxazaborolidine as Catalyst

Pharmacokinetics and tissue distribution of neurotrophin 3 after intracochlear delivery

Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide

Anti-Group B Streptococcus Glycan-Conjugate Vaccines Using Pilus Protein GBS80 As Carrier and Antigen: Comparing Lysine and Tyrosine-directed Conjugation

Simple, Catalytic Enantioselective Syntheses of Estrone and Desogestrel

The First In(OTf)3-Catalyzed Conversion of Kinetically Formed Homoallylic Alcohols into the Thermodynamically Preferred Regioisomers: Application to the Synthesis of 22α-Sterols

Diverse Cyclization Catalyzed by In(OTf)3 for the Convergent Assembly of Substituted Tetrahydrofurans and Tetrahydropyrans

New hypotheses about the structure-function of proprotein convertase subtilisin/kexin type 9: Analysis of the epidermal growth factor-like repeat A docking site using WaterMap

Frontispiz: Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

Stereocontrolled Synthesis of Linear 22R-Homoallylic Sterols via a Triflic Acid-Catalyzed 2-Oxonia Cope Rearrangement

Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors

Synthetic Studies toward Anisatin: A Formal Synthesis of (±)-8-Deoxyanisatin

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