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Structural Basis for Apelin Control of the Human Apelin Receptor

Structure (London), 2017-06, Vol.25 (6), p.858-866.e4

2017

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Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

Cell research, 2020-05, Vol.30 (5), p.436-445

2020

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Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands

Biochemical journal, 2009-11, Vol.424 (1), p.39-45

2009

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APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells

Biochemical journal, 2022-02, Vol.479 (3), p.385-399

2022

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Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice

Biochemical journal, 2020-09, Vol.477 (17), p.3313-3327

2020

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Fragment-Based Computational Method for Designing GPCR Ligands

Journal of chemical information and modeling, 2020-09, Vol.60 (9), p.4339-4349

2020

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Identification of Surrogate Agonists and Antagonists for Orphan G-Protein-Coupled Receptor GPR139

Journal of biomolecular screening, 2009-08, Vol.14 (7), p.789-797

2009

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GPCR structure and function relationship: identification of a biased apelin receptor mutant

Biochemical journal, 2018-12, Vol.475 (23), p.3813-3826

2018

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Different conformational responses of the β2-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline

National science review, 2021-09, Vol.8 (9), p.nwaa284

2021

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Structure-guided discovery of a single-domain antibody agonist against human apelin receptor

Science advances, 2020-01, Vol.6 (3), p.eaax7379-eaax7379

2020

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A general Fc engineering platform for the next generation of antibody therapeutics

Theranostics, 2021, Vol.11 (4), p.1901-1917

2021

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Author Correction: Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

Cell research, 2020-05, Vol.30 (5), p.455-455

2020

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Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors

Communications biology, 2020-03, Vol.3 (1), p.146-146, Article 146

2020

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1391-1394

2003

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Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79

The Journal of biological chemistry, 2001-05, Vol.276 (18), p.15192-15199

2001

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Beta-arrestin 1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14889

2001

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A homogeneous G protein-coupled receptor ligand binding assay based on time-resolved fluorescence resonance energy transfer

Assay and drug development technologies, 2008-08, Vol.6 (4), p.543-550

2008

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Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12559-12564

1999

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β-Arrestin1 Modulates Lymphoid Enhancer Factor Transcriptional Activity through Interaction with Phosphorylated Dishevelled Proteins

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.14889-14894

2001

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Induction of substrate specificity shifts by placement of alanine insertions within the consensus amphipathic region of the Escherichia coli GABA (gamma-aminobutyric acid) transporter encoded by gabP

Biochemical journal, 2003-12, Vol.376 (Pt 3), p.645-653

2003

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Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling

The Journal of biological chemistry, 2001-11, Vol.276 (48), p.45145-45152

2001

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G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95

The Journal of biological chemistry, 2002-01, Vol.277 (2), p.1607-1613

2002

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Identification of the Endophilins (SH3p4p8/p13) as Novel Binding Partners for the β 1-Adrenergic Receptor

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12559-12564

1999

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G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95

The Journal of biological chemistry, 2002-01, Vol.277 (2), p.1607-1613

2002

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Structural Basis for Apelin Control of the Human Apelin Receptor

Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands

APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells

Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice

Fragment-Based Computational Method for Designing GPCR Ligands

Identification of Surrogate Agonists and Antagonists for Orphan G-Protein-Coupled Receptor GPR139

GPCR structure and function relationship: identification of a biased apelin receptor mutant

Different conformational responses of the β2-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline

Structure-guided discovery of a single-domain antibody agonist against human apelin receptor

A general Fc engineering platform for the next generation of antibody therapeutics

Author Correction: Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors

Cardiovascular response to small-molecule APJ activation

Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79

Beta-arrestin 1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins

A homogeneous G protein-coupled receptor ligand binding assay based on time-resolved fluorescence resonance energy transfer

Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor

β-Arrestin1 Modulates Lymphoid Enhancer Factor Transcriptional Activity through Interaction with Phosphorylated Dishevelled Proteins

Induction of substrate specificity shifts by placement of alanine insertions within the consensus amphipathic region of the Escherichia coli GABA (gamma-aminobutyric acid) transporter encoded by gabP

Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling

G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95

Identification of the Endophilins (SH3p4p8/p13) as Novel Binding Partners for the β 1-Adrenergic Receptor

G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95

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