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Design, Synthesis and Cytotoxicity of Thiazole-Based Stilbene Analogs as Novel DNA Topoisomerase IB Inhibitors

Molecules (Basel, Switzerland), 2022-02, Vol.27 (3), p.1009

2022

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Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors

ChemMedChem, 2023-05, Vol.18 (10), p.e202200593-n/a

2023

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Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents

Journal of medicinal chemistry, 2018-11, Vol.61 (22), p.9908-9930

2018

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Synthesis and biological evaluation of novel indole-pyrazoline hybrid derivatives as potential topoisomerase 1 inhibitors

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (4), p.126925-126925, Article 126925

2020

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Synthesis of Methoxy‑, Methylenedioxy‑, Hydroxy‑, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7617-7629

2021

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Secondary metabolites from Isodon ternifolius (D. Don) Kudo and their anticancer activity as DNA topoisomerase IB and Tyrosyl-DNA phosphodiesterase 1 inhibitors

Bioorganic & medicinal chemistry, 2020-06, Vol.28 (11), p.115527-115527, Article 115527

2020

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The oligonucleotide-based fluorescence assay for the discovery of tyrosyl-DNA phosphodiesterase 2 inhibitors

Dyes and pigments, 2024-08, Vol.227, p.112173, Article 112173

2024

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Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors

European journal of medicinal chemistry, 2019-09, Vol.178, p.81-92

2019

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The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors

Bioorganic chemistry, 2021-06, Vol.111, p.104881-104881, Article 104881

2021

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Novel stilbene analogues containing thiazole moiety: Synthesis, biological evaluation and docking study

Journal of molecular structure, 2019-03, Vol.1180, p.780-786

2019

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Research on driver fatigue detection technology based on eye state

Hu, De Xuan

2010

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Plantar Pressure Changes and Correlating Risk Factors in Chinese Patients with Type 2 Diabetes： Preliminary 2-year Results of a Prospective Study

Chinese medical journal, 2015-12, Vol.128 (24), p.3283-3291

2015

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Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting β1 subunit expression and disrupting proteasome assembly

Acta pharmacologica Sinica, 2016-07, Vol.37 (7), p.908-918

2016

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An Exceptional Thermally Induced Four‐State Nonlinear Optical Switch Arising from Stepwise Molecular Dynamic Changes in a New Hybrid Salt

Angewandte Chemie International Edition, 2022-01, Vol.61 (2), p.e202110082-n/a

International ed. in English, 2022

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Enhanced energy deposition of laser-produced proton beams in high-density plasmas due to beam density self-steepening

Physics of plasmas, 2024-09, Vol.31 (9)

2024

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Optimization of e+/e− pair yield during the interaction of a Doppler-boosted laser with a solid-density plasma

AIP advances, 2023-07, Vol.13 (7), p.075214-075214-7

2023

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X-ray beams produced by hot electrons with directional drift velocity in fusion plasmas

Plasma physics and controlled fusion, 2021-12, Vol.63 (12), p.125029

2021

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Gamma-ray beam produced by a plasma lens focused electron bunch

Physics of plasmas, 2020-02, Vol.27 (2)

2020

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Modulation of ion beams in two-component plasmas: Three-dimensional particle-in-cell simulation

Physics of plasmas, 2019-09, Vol.26 (9)

2019

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A Crystalline Supramolecular Rotor Functioned by Dual Ultrasmall Polar Rotators

Chinese journal of chemistry, 2022-08, Vol.40 (16), p.1917-1923

2022

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An Exceptional Thermally Induced Four‐State Nonlinear Optical Switch Arising from Stepwise Molecular Dynamic Changes in a New Hybrid Salt

Angewandte Chemie, 2022-01, Vol.134 (2), p.n/a

2022

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A tree shrew model for steroid-associated osteonecrosis

Dōngwùxué yánjiū, 2020-09, Vol.41 (5), p.564-568

2020

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Iris location algorithm based on improved particle swarm optimization

Guang xue, jing mi gong cheng, 2014, Vol.22 (4), p.1056-1063

2014

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Iris location algorithm by counting distances

Guang xue, jing mi gong cheng, 2012-11, Vol.20 (11), p.2516-2522

2012

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Photo‑, Thermo‑, and Vapochromic Behavior in a 2,4,6-Tris-2-pyridyl-1,3,5-triazine Ligand-Based Zn(II) Complex

Crystal growth & design, 2024-10, Vol.24 (20), p.8563-8568

2024

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Design, Synthesis and Cytotoxicity of Thiazole-Based Stilbene Analogs as Novel DNA Topoisomerase IB Inhibitors

Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors

Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents

Synthesis and biological evaluation of novel indole-pyrazoline hybrid derivatives as potential topoisomerase 1 inhibitors

Synthesis of Methoxy‑, Methylenedioxy‑, Hydroxy‑, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

Secondary metabolites from Isodon ternifolius (D. Don) Kudo and their anticancer activity as DNA topoisomerase IB and Tyrosyl-DNA phosphodiesterase 1 inhibitors

The oligonucleotide-based fluorescence assay for the discovery of tyrosyl-DNA phosphodiesterase 2 inhibitors

Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors

The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors

Novel stilbene analogues containing thiazole moiety: Synthesis, biological evaluation and docking study

Research on driver fatigue detection technology based on eye state

Plantar Pressure Changes and Correlating Risk Factors in Chinese Patients with Type 2 Diabetes： Preliminary 2-year Results of a Prospective Study

Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibiting β1 subunit expression and disrupting proteasome assembly

An Exceptional Thermally Induced Four‐State Nonlinear Optical Switch Arising from Stepwise Molecular Dynamic Changes in a New Hybrid Salt

Enhanced energy deposition of laser-produced proton beams in high-density plasmas due to beam density self-steepening

Optimization of e+/e− pair yield during the interaction of a Doppler-boosted laser with a solid-density plasma

X-ray beams produced by hot electrons with directional drift velocity in fusion plasmas

Gamma-ray beam produced by a plasma lens focused electron bunch

Modulation of ion beams in two-component plasmas: Three-dimensional particle-in-cell simulation

A Crystalline Supramolecular Rotor Functioned by Dual Ultrasmall Polar Rotators

An Exceptional Thermally Induced Four‐State Nonlinear Optical Switch Arising from Stepwise Molecular Dynamic Changes in a New Hybrid Salt

A tree shrew model for steroid-associated osteonecrosis

Iris location algorithm based on improved particle swarm optimization

Iris location algorithm by counting distances

Photo‑, Thermo‑, and Vapochromic Behavior in a 2,4,6-Tris-2-pyridyl-1,3,5-triazine Ligand-Based Zn(II) Complex

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