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Improving categorical endpoint longitudinal exposure–response modeling through the joint modeling with a related endpoint

Journal of pharmacokinetics and pharmacodynamics, 2022-06, Vol.49 (3), p.283-291

2022

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Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis

European journal of clinical pharmacology, 2009-12, Vol.65 (12), p.1211-1228

2009

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Likelihood comparisons in bounded outcome score analysis must be internally consistent

Journal of pharmacokinetics and pharmacodynamics, 2024-07

Hu, Chuanpu

2024

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Variability and uncertainty: interpretation and usage of pharmacometric simulations and intervals

Journal of pharmacokinetics and pharmacodynamics, 2022-10, Vol.49 (5), p.487-491

Hu, Chuanpu

2022

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On the Comparison of Methods in Analyzing Bounded Outcome Score Data

The AAPS journal, 2019-11, Vol.21 (6), p.102-102, Article 102

Hu, Chuanpu

2019

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Pharmacokinetic/Pharmacodynamic Analysis of Guselkumab for Treatment of Palmoplantar Pustulosis: Clinical Implications of Guselkumab Dose, Disease Severity, and Smoking in Japanese Patients

Journal of clinical pharmacology, 2022-02, Vol.62 (2), p.182-189

2022

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Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

Journal of pharmacokinetics and pharmacodynamics, 2016-02, Vol.43 (1), p.45-54

2016

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Applying Beta Distribution in Analyzing Bounded Outcome Score Data

The AAPS journal, 2020-03, Vol.22 (3), p.61-61, Article 61

2020

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Application of Beta-Distribution and Combined Uniform and Binomial Methods in Longitudinal Modeling of Bounded Outcome Score Data

The AAPS journal, 2020-07, Vol.22 (5), p.95-95, Article 95

2020

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Facilitating Longitudinal Exposure-Response Modeling of a Composite Endpoint Using the Joint Modeling of Sparsely and Frequently Collected Subcomponents

The AAPS journal, 2020-05, Vol.22 (4), p.79-79, Article 79

2020

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Variability of Target-controlled infusion is less than the variability after bolus injection

Anesthesiology (Philadelphia), 2005-03, Vol.102 (3), p.639-645

2005

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A joint model for nonlinear longitudinal data with informative dropout

Journal of pharmacokinetics and pharmacodynamics, 2003-02, Vol.30 (1), p.83-103

2003

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Latent variable indirect response modeling of clinical efficacy endpoints with combination therapy: application to guselkumab and golimumab in patients with ulcerative colitis

Journal of pharmacokinetics and pharmacodynamics, 2023-04, Vol.50 (2), p.133-144

2023

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Landmark and longitudinal exposure–response analyses in drug development

Journal of pharmacokinetics and pharmacodynamics, 2017-10, Vol.44 (5), p.503-507

2017

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Erratum to: Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

Journal of pharmacokinetics and pharmacodynamics, 2016-02, Vol.43 (1), p.55-55

2016

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Population Pharmacokinetics and Exposure‐Response Modeling Analyses of Ustekinumab in Adults With Moderately to Severely Active Ulcerative Colitis

Journal of clinical pharmacology, 2020-07, Vol.60 (7), p.889-902

2020

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Extrapolating Pharmacodynamic Effects From Adults to Pediatrics: A Case Study of Ustekinumab in Pediatric Patients With Moderate to Severe Plaque Psoriasis

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.131-139

2021

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Pharmacokinetic Modeling and Predictive Performance: Practical Considerations for Therapeutic Monoclonal Antibodies

European journal of drug metabolism and pharmacokinetics, 2021-09, Vol.46 (5), p.595-600

2021

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No Recipe for Quantitative Systems Pharmacology Model Validation, but a Balancing Act Between Risk and Cost

Clinical pharmacology and therapeutics, 2024-01, Vol.115 (1), p.25-28

2024

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Improvement in latent variable indirect response modeling of multiple categorical clinical endpoints: application to modeling of guselkumab treatment effects in psoriatic patients

Journal of pharmacokinetics and pharmacodynamics, 2017-10, Vol.44 (5), p.437-448

2017

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Confirmatory population pharmacokinetic analysis for bapineuzumab phase 3 studies in patients with mild to moderate Alzheimer's disease

Journal of clinical pharmacology, 2015-02, Vol.55 (2), p.221-229

2015

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Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL‐23, in Patients with Moderate to Severe Plaque Psoriasis

Journal of clinical pharmacology, 2018-05, Vol.58 (5), p.613-627

2018

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Confirmatory Population Pharmacokinetic Analysis for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin‐6, in Patients With Moderately to Severely Active Rheumatoid Arthritis

Journal of clinical pharmacology, 2018-07, Vol.58 (7), p.939-951

2018

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Population pharmacokinetics : A regulatory perspective

Clinical pharmacokinetics, 1999-07, Vol.37 (1), p.41-58

1999

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Exposure‐Response Modeling Analyses for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin 6, in Patients With Moderately to Severely Active Rheumatoid Arthritis

Journal of clinical pharmacology, 2018-11, Vol.58 (11), p.1501-1515

2018

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Improving categorical endpoint longitudinal exposure–response modeling through the joint modeling with a related endpoint

Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis

Likelihood comparisons in bounded outcome score analysis must be internally consistent

Variability and uncertainty: interpretation and usage of pharmacometric simulations and intervals

On the Comparison of Methods in Analyzing Bounded Outcome Score Data

Pharmacokinetic/Pharmacodynamic Analysis of Guselkumab for Treatment of Palmoplantar Pustulosis: Clinical Implications of Guselkumab Dose, Disease Severity, and Smoking in Japanese Patients

Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

Applying Beta Distribution in Analyzing Bounded Outcome Score Data

Application of Beta-Distribution and Combined Uniform and Binomial Methods in Longitudinal Modeling of Bounded Outcome Score Data

Facilitating Longitudinal Exposure-Response Modeling of a Composite Endpoint Using the Joint Modeling of Sparsely and Frequently Collected Subcomponents

Variability of Target-controlled infusion is less than the variability after bolus injection

A joint model for nonlinear longitudinal data with informative dropout

Latent variable indirect response modeling of clinical efficacy endpoints with combination therapy: application to guselkumab and golimumab in patients with ulcerative colitis

Landmark and longitudinal exposure–response analyses in drug development

Erratum to: Improvement in latent variable indirect response joint modeling of a continuous and a categorical clinical endpoint in rheumatoid arthritis

Population Pharmacokinetics and Exposure‐Response Modeling Analyses of Ustekinumab in Adults With Moderately to Severely Active Ulcerative Colitis

Extrapolating Pharmacodynamic Effects From Adults to Pediatrics: A Case Study of Ustekinumab in Pediatric Patients With Moderate to Severe Plaque Psoriasis

Pharmacokinetic Modeling and Predictive Performance: Practical Considerations for Therapeutic Monoclonal Antibodies

No Recipe for Quantitative Systems Pharmacology Model Validation, but a Balancing Act Between Risk and Cost

Improvement in latent variable indirect response modeling of multiple categorical clinical endpoints: application to modeling of guselkumab treatment effects in psoriatic patients

Confirmatory population pharmacokinetic analysis for bapineuzumab phase 3 studies in patients with mild to moderate Alzheimer's disease

Population Pharmacokinetic Modeling of Guselkumab, a Human IgG1λ Monoclonal Antibody Targeting IL‐23, in Patients with Moderate to Severe Plaque Psoriasis

Confirmatory Population Pharmacokinetic Analysis for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin‐6, in Patients With Moderately to Severely Active Rheumatoid Arthritis

Population pharmacokinetics : A regulatory perspective

Exposure‐Response Modeling Analyses for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin 6, in Patients With Moderately to Severely Active Rheumatoid Arthritis

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