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Global targeting of functional tyrosines using sulfur-triazole exchange chemistry

Nature chemical biology, 2020-02, Vol.16 (2), p.150-159

2020

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Voices: Challenges and opportunities for bioorthogonal chemistry

Cell chemical biology, 2024-03, Vol.31 (3), p.380-382

2024

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Liganding Functional Tyrosine Sites on Proteins Using Sulfur–Triazole Exchange Chemistry

Journal of the American Chemical Society, 2020-05, Vol.142 (18), p.8270-8280

2020

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Isoform-selective activity-based profiling of ERK signaling

Chemical science (Cambridge), 2018-03, Vol.9 (9), p.2419-2431

2018

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Activity-Based Protein Profiling

1st ed. 2019., 2019

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Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

Nature chemical biology, 2020-02, Vol.16 (2), p.170-178

2020

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The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14924-14929

2014

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Advances in Activity‐Based Protein Profiling of Functional Tyrosines in Proteomes

Israel journal of chemistry, 2023-03, Vol.63 (3-4), p.n/a

2023

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Discovery of a Cell‐Active SuTEx Ligand of Prostaglandin Reductase 2

Chembiochem : a European journal of chemical biology, 2021-06, Vol.22 (12), p.2134-2139

2021

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Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles

Chembiochem : a European journal of chemical biology, 2024-08, Vol.25 (16), p.e202400382

2024

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Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

Nature chemical biology, 2011-05, Vol.7 (7), p.469-478

2011

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Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy

The Journal of pharmacology and experimental therapeutics, 2018-07, Vol.366 (1), p.169-183

2018

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Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes

Chemical science (Cambridge), 2021-01, Vol.12 (9), p.3295-337

2021

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Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-06, Vol.1864 (6), p.907-921

2019

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Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

Nature chemical biology, 2014-02, Vol.10 (2), p.113-121

2014

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Chemoproteomic capture of RNA binding activity in living cells

Nature communications, 2023-10, Vol.14 (1), p.6282-6282, Article 6282

2023

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RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

Cell reports (Cambridge), 2021-07, Vol.36 (4), p.109451-109451, Article 109451

2021

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Analyzing the dynamic bacterial glycome with a lectin microarray approach

Nature chemical biology, 2006-03, Vol.2 (3), p.153-157

2006

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Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4338-4343

2014

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ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice

Neuron (Cambridge, Mass.), 2014-07, Vol.83 (2), p.361-371

2014

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Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

Molecular pharmaceutics, 2018-03, Vol.15 (3), p.721-728

2018

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Shining a Light on Phenotypic Drug Discovery

Cell chemical biology, 2021-02, Vol.28 (2), p.115-117

Hsu, Ku-Lung

2021

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Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase

The Journal of pharmacology and experimental therapeutics, 2019-12, Vol.371 (3), p.652-662

2019

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Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8257-8269

2013

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A lectin microarray approach for the rapid analysis of bacterial glycans

Nature protocols, 2006-07, Vol.1 (2), p.543-549

2006

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Global targeting of functional tyrosines using sulfur-triazole exchange chemistry

Voices: Challenges and opportunities for bioorthogonal chemistry

Liganding Functional Tyrosine Sites on Proteins Using Sulfur–Triazole Exchange Chemistry

Isoform-selective activity-based profiling of ERK signaling

Activity-Based Protein Profiling

Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase

Advances in Activity‐Based Protein Profiling of Functional Tyrosines in Proteomes

Discovery of a Cell‐Active SuTEx Ligand of Prostaglandin Reductase 2

Imidazoles are Tunable Nucleofuges for Developing Tyrosine-Reactive Electrophiles

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy

Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes

Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond

Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes

Chemoproteomic capture of RNA binding activity in living cells

RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

Analyzing the dynamic bacterial glycome with a lectin microarray approach

Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode

ABHD6 Blockade Exerts Antiepileptic Activity in PTZ-Induced Seizures and in Spontaneous Seizures in R6/2 Mice

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

Shining a Light on Phenotypic Drug Discovery

Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase

Development and Optimization of Piperidyl-1,2,3-Triazole Ureas as Selective Chemical Probes of Endocannabinoid Biosynthesis

A lectin microarray approach for the rapid analysis of bacterial glycans

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