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New mechanistic and functional insights into DNA topoisomerases

Annual review of biochemistry, 2013-01, Vol.82 (1), p.139-170

2013

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Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging

Scientific reports, 2017-03, Vol.7 (1), p.45474-45474, Article 45474

2017

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Topoisomerase IIIα and Bloom's Helicase Can Resolve a Mobile Double Holliday Junction Substrate through Convergent Branch Migration

Proceedings of the National Academy of Sciences - PNAS, 2006-07, Vol.103 (30), p.11118-11123

2006

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Drosophila mitochondrial topoisomerase III alpha affects the aging process via maintenance of mitochondrial function and genome integrity

Journal of biomedical science, 2016-04, Vol.23 (38), p.38-38, Article 38

2016

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Helicase-appended Topoisomerases: New Insight into the Mechanism of Directional Strand Transfer

The Journal of biological chemistry, 2009-11, Vol.284 (45), p.30737-30741

2009

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Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1

PLoS biology, 2016-01, Vol.14 (1), p.e1002349-e1002349

2016

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Drosophila topo IIIα is required for the maintenance of mitochondrial genome and male germ-line stem cells

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (14), p.6228-6233

2010

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Top3α is required during the convergent migration step of double Holliday junction dissolution

PloS one, 2014, Vol.9 (1), p.e83582-e83582

2014

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Synthesis and dissolution of hemicatenanes by type IA DNA topoisomerases

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.E3587-E3594

2013

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Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction

The Journal of biological chemistry, 2017-03, Vol.292 (10), p.4313-4325

2017

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Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle

The Journal of cell biology, 2008-06, Vol.181 (5), p.777-790

2008

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Toward discovering new anti-cancer agents targeting topoisomerase IIα: a facile screening strategy adaptable to high throughput platform

PloS one, 2014-05, Vol.9 (5), p.e97008

2014

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Drosophila homologue of the Rothmund–Thomson syndrome gene: Essential function in DNA replication during development

Developmental biology, 2008-11, Vol.323 (1), p.130-142

2008

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Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamide

The EMBO journal, 2006-06, Vol.25 (11), p.2397-2408

2006

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ISG15 as a novel tumor biomarker for drug sensitivity

Molecular cancer therapeutics, 2008-06, Vol.7 (6), p.1430-1439

2008

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Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.4840-4845

2007

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Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts

Cellular signalling, 2018-07, Vol.47, p.16-26

2018

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RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

Nucleic acids research, 2016-07, Vol.44 (13), p.6335-6349

2016

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Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

The Journal of clinical investigation, 2017-08, Vol.127 (8), p.2982-2997

2017

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DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.E5544-E5551

2016

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Single-molecule Förster resonance energy transfer (FRET) analysis discloses the dynamics of the DNA–topoisomerase II (Top2) interaction in the presence of TOP2-targeting agents

The Journal of biological chemistry, 2017-07, Vol.292 (30), p.12589-12598

2017

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Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective

Nucleic acids research, 2009-02, Vol.37 (3), p.712-720

2009

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Nucleotide- and Stoichiometry-dependent DNA Supercoiling by Reverse Gyrase

The Journal of biological chemistry, 2005-05, Vol.280 (21), p.20467-20475

2005

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The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

The Journal of biological chemistry, 2016-06, Vol.291 (25), p.13216-13228

2016

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Synthesis of Hemicatenanes for the Study of Type IA Topoisomerases

Methods in molecular biology (Clifton, N.J.), 2018, Vol.1703, p.153

2018

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New mechanistic and functional insights into DNA topoisomerases

Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging

Topoisomerase IIIα and Bloom's Helicase Can Resolve a Mobile Double Holliday Junction Substrate through Convergent Branch Migration

Drosophila mitochondrial topoisomerase III alpha affects the aging process via maintenance of mitochondrial function and genome integrity

Helicase-appended Topoisomerases: New Insight into the Mechanism of Directional Strand Transfer

Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1

Drosophila topo IIIα is required for the maintenance of mitochondrial genome and male germ-line stem cells

Top3α is required during the convergent migration step of double Holliday junction dissolution

Synthesis and dissolution of hemicatenanes by type IA DNA topoisomerases

Ribosomal Protein S3 Negatively Regulates Unwinding Activity of RecQ-like Helicase 4 through Their Physical Interaction

Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle

Toward discovering new anti-cancer agents targeting topoisomerase IIα: a facile screening strategy adaptable to high throughput platform

Drosophila homologue of the Rothmund–Thomson syndrome gene: Essential function in DNA replication during development

Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamide

ISG15 as a novel tumor biomarker for drug sensitivity

Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II

Wuho/WDR4 deficiency inhibits cell proliferation and induces apoptosis via DNA damage in mouse embryonic fibroblasts

RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3

Single-molecule Förster resonance energy transfer (FRET) analysis discloses the dynamics of the DNA–topoisomerase II (Top2) interaction in the presence of TOP2-targeting agents

Analysis of the eukaryotic topoisomerase II DNA gate: a single-molecule FRET and structural perspective

Nucleotide- and Stoichiometry-dependent DNA Supercoiling by Reverse Gyrase

The C-terminal 20 Amino Acids of Drosophila Topoisomerase 2 Are Required for Binding to a BRCA1 C Terminus (BRCT) Domain-containing Protein, Mus101, and Fidelity of DNA Segregation

Synthesis of Hemicatenanes for the Study of Type IA Topoisomerases

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