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A clarion call for high‐quality research on gender dysphoric youth

Acta Paediatrica, 2023-11, Vol.112 (11), p.2266-2268

Hruz, Paul W.

2023

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Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Science signaling, 2016-02, Vol.9 (416), p.ra21

2016

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Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

The Journal of biological chemistry, 2016-08, Vol.291 (33), p.17271-17282

2016

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HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4

PloS one, 2011-09, Vol.6 (9), p.e25237

2011

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SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

Scientific reports, 2016-12, Vol.6 (1), p.38586-38586, Article 38586

2016

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Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

Gastroenterology (New York, N.Y. 1943), 2020-04, Vol.158 (5), p.1402-1416.e2

2020

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Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

PloS one, 2019-05, Vol.14 (5), p.e0216457

2019

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TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

Autophagy, 2018-11, Vol.14 (11), p.1959-1975

2018

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Development of GLUT4-selective antagonists for multiple myeloma therapy

European journal of medicinal chemistry, 2017-10, Vol.139, p.573-586

2017

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GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle

Cardiovascular diabetology, 2012-06, Vol.11 (1), p.63-63, Article 63

2012

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Molecular mechanisms for insulin resistance in treated HIV-infection

Baillière's best practice & research. Clinical endocrinology & metabolism, 2011-06, Vol.25 (3), p.459-468

Hruz, Paul W., MD, PhD

2011

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Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy

PloS one, 2011-02, Vol.6 (2), p.e17178

2011

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Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

Scientific reports, 2018-04, Vol.8 (1), p.6475-10, Article 6475

2018

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MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

Scientific reports, 2017-08, Vol.7 (1), p.8400-11, Article 8400

2017

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Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake

Biomolecules (Basel, Switzerland), 2022-11, Vol.12 (12), p.1734

2022

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HIV and Endocrine Disorders

Endocrinology and metabolism clinics of North America, 2014-09, Vol.43 (3), p.xvii-xviii

Hruz, Paul W., MD, PhD

2014

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The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy: Cellular Mechanisms and Clinical Implications

Toxicologic pathology, 2009-01, Vol.37 (1), p.65-77

2009

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Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

The Linacre quarterly, 2020-02, Vol.87 (1), p.34-42

Hruz, Paul W.

2020

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Genetic Disruption of Myostatin Reduces the Development of Proatherogenic Dyslipidemia and Atherogenic Lesions In Ldlr Null Mice

Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1739-1748

2009

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Letter to the Editor from William J. Malone et al: “Proper Care of Transgender and Gender-diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective”

The journal of clinical endocrinology and metabolism, 2021-08, Vol.106 (8), p.e3287-e3288

2021

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A Structural Basis for the Acute Effects of HIV Protease Inhibitors on GLUT4 Intrinsic Activity

The Journal of biological chemistry, 2004-12, Vol.279 (53), p.55147-55152

2004

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Delayed Hepatocellular Mitotic Progression and Impaired Liver Regeneration in Early Growth Response-1-deficient Mice

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.43107-43116

2004

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HIV Protease Inhibitors Acutely Impair Glucose-Stimulated Insulin Release

Diabetes (New York, N.Y.), 2003-07, Vol.52 (7), p.1695-1700

2003

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Indinavir Induces Acute and Reversible Peripheral Insulin Resistance in Rats

Diabetes (New York, N.Y.), 2002-04, Vol.51 (4), p.937-942

2002

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GS-8374, a Novel HIV Protease Inhibitor, Does Not Alter Glucose Homeostasis in Cultured Adipocytes or in a Healthy-Rodent Model System

Antimicrobial Agents and Chemotherapy, 2011-04, Vol.55 (4), p.1377-1382

2011

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A clarion call for high‐quality research on gender dysphoric youth

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

Development of GLUT4-selective antagonists for multiple myeloma therapy

GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle

Molecular mechanisms for insulin resistance in treated HIV-infection

Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake

HIV and Endocrine Disorders

The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy: Cellular Mechanisms and Clinical Implications

Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

Genetic Disruption of Myostatin Reduces the Development of Proatherogenic Dyslipidemia and Atherogenic Lesions In Ldlr Null Mice

Letter to the Editor from William J. Malone et al: “Proper Care of Transgender and Gender-diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective”

A Structural Basis for the Acute Effects of HIV Protease Inhibitors on GLUT4 Intrinsic Activity

Delayed Hepatocellular Mitotic Progression and Impaired Liver Regeneration in Early Growth Response-1-deficient Mice

HIV Protease Inhibitors Acutely Impair Glucose-Stimulated Insulin Release

Indinavir Induces Acute and Reversible Peripheral Insulin Resistance in Rats

GS-8374, a Novel HIV Protease Inhibitor, Does Not Alter Glucose Homeostasis in Cultured Adipocytes or in a Healthy-Rodent Model System

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