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A clarion call for high‐quality research on gender dysphoric youth

Acta Paediatrica, 2023-11, Vol.112 (11), p.2266-2268

Hruz, Paul W.

2023

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HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4

PloS one, 2011-09, Vol.6 (9), p.e25237

2011

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Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Science signaling, 2016-02, Vol.9 (416), p.ra21

2016

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Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

The Journal of biological chemistry, 2016-08, Vol.291 (33), p.17271-17282

2016

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Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

The Linacre quarterly, 2020-02, Vol.87 (1), p.34-42

Hruz, Paul W.

2020

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Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

PloS one, 2019-05, Vol.14 (5), p.e0216457

2019

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Letter to the Editor from William J. Malone et al: “Proper Care of Transgender and Gender-diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective”

The journal of clinical endocrinology and metabolism, 2021-08, Vol.106 (8), p.e3287-e3288

2021

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SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

Scientific reports, 2016-12, Vol.6 (1), p.38586-38586, Article 38586

2016

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GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle

Cardiovascular diabetology, 2012-06, Vol.11 (1), p.63-63, Article 63

2012

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Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

Gastroenterology (New York, N.Y. 1943), 2020-04, Vol.158 (5), p.1402-1416.e2

2020

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TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

Autophagy, 2018-11, Vol.14 (11), p.1959-1975

2018

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Development of GLUT4-selective antagonists for multiple myeloma therapy

European journal of medicinal chemistry, 2017-10, Vol.139, p.573-586

2017

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Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy

PloS one, 2011-02, Vol.6 (2), p.e17178

2011

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Molecular mechanisms for insulin resistance in treated HIV-infection

Baillière's best practice & research. Clinical endocrinology & metabolism, 2011-06, Vol.25 (3), p.459-468

Hruz, Paul W., MD, PhD

2011

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Evaluating the Efficacy of GLUT Inhibitors Using a Seahorse Extracellular Flux Analyzer

Methods in molecular biology (Clifton, N.J.), 2018-01, Vol.1713, p.69

2018

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In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy

The Journal of biological chemistry, 2015-06, Vol.290 (23), p.14441-14453

2015

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Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake

Biomolecules (Basel, Switzerland), 2022-11, Vol.12 (12), p.1734

2022

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The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir

Antimicrobial agents and chemotherapy, 2015-10, Vol.59 (10), p.6203-6209

2015

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Expression, purification, and functional characterization of the insulin‐responsive facilitative glucose transporter GLUT4

Protein science, 2015-12, Vol.24 (12), p.2008-2019

2015

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Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

Scientific reports, 2018-04, Vol.8 (1), p.6475-10, Article 6475

2018

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Effects of the HIV Protease Inhibitor Ritonavir on GLUT4 Knock-out Mice

The Journal of biological chemistry, 2010-11, Vol.285 (47), p.36395-36400

2010

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MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

Scientific reports, 2017-08, Vol.7 (1), p.8400-11, Article 8400

2017

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Letter to the Editor: “Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline”

The journal of clinical endocrinology and metabolism, 2019-03, Vol.104 (3), p.686-687

2019

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Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice

Hepatology (Baltimore, Md.), 2010-12, Vol.52 (6), p.2109-2117

2010

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Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice

Hepatology (Baltimore, Md.), 2004-12, Vol.40 (6), p.1322-1332

2004

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A clarion call for high‐quality research on gender dysphoric youth

HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

Deficiencies in Scientific Evidence for Medical Management of Gender Dysphoria

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

Letter to the Editor from William J. Malone et al: “Proper Care of Transgender and Gender-diverse Persons in the Setting of Proposed Discrimination: A Policy Perspective”

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle

Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice

TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

Development of GLUT4-selective antagonists for multiple myeloma therapy

Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy

Molecular mechanisms for insulin resistance in treated HIV-infection

Evaluating the Efficacy of GLUT Inhibitors Using a Seahorse Extracellular Flux Analyzer

In Silico Modeling-based Identification of Glucose Transporter 4 (GLUT4)-selective Inhibitors for Cancer Therapy

Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake

The Glucose Transporter PfHT1 Is an Antimalarial Target of the HIV Protease Inhibitor Lopinavir

Expression, purification, and functional characterization of the insulin‐responsive facilitative glucose transporter GLUT4

Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia

Effects of the HIV Protease Inhibitor Ritonavir on GLUT4 Knock-out Mice

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis

Letter to the Editor: “Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline”

Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice

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