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An alternative approach to validation of liquid chromatography-mass spectrometry methods for the quantification of endogenous compounds

Journal of Chromatography A, 2023-08, Vol.1705, p.464173, Article 464173

2023

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High-throughput salting-out assisted liquid-liquid extraction using a 3D printed device and its application in the quantification of ibrutinib and its metabolite PCI-45227 in human serum

Journal of pharmaceutical and biomedical analysis, 2022-09, Vol.219, p.114923-114923, Article 114923

2022

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Synthesis of [13C6]‐ibrutinib

Journal of labelled compounds & radiopharmaceuticals, 2021-11, Vol.64 (13), p.500-512

2021

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Beyond the Meaning of Zines: A Case Study of the Role of Materiality in four Prague-Based Zine Assemblages

Communication, culture & critique, 2021-06, Vol.14 (2), p.252-273

2021

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Direct Multi‐Deuterium Labelling of Pirtobrutinib

Journal of labelled compounds & radiopharmaceuticals, 2024-07, Vol.67 (9), p.314-323

2024

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Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

International journal of molecular sciences, 2021-06, Vol.22 (12), p.6468

2021

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Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer

Clinical pharmacokinetics, 2015-05, Vol.54 (5), p.503-515

2015

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Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats

Frontiers in physiology, 2022-03, Vol.13, p.859294-859294

2022

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Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines

Arabian journal of chemistry, 2022-05, Vol.15 (5), p.103746, Article 103746

2022

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In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2020-10, Vol.190, p.113519, Article 113519

2020

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Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis

Frontiers in pharmacology, 2023-01, Vol.14, p.1116422-1116422

2023

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Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver

International journal of molecular sciences, 2020-11, Vol.21 (23), p.9021

2020

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Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats

World journal of gastroenterology : WJG, 2017-11, Vol.23 (43), p.7678-7692

2017

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Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-10, Vol.936, p.48-56

2013

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Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane

Journal of molecular and cellular cardiology, 2016-02, Vol.91, p.92-103

2016

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Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro

Planta medica, 2016-11, Vol.82 (16), p.1416-1424

2016

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Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways

The Journal of pharmacology and experimental therapeutics, 2012-11, Vol.343 (2), p.468-478

2012

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Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits

Toxicology (Amsterdam), 2013-09, Vol.311 (3), p.191-204

2013

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[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study

Journal of organometallic chemistry, 2015-04, Vol.782, p.42-51

2015

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Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study

Gastroenterology research and practice, 2019, Vol.2019 (2019), p.1-7

2019

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HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-l-arginine using core–shell particle column and LC–MS/MS identification of principal metabolite in rat plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-01, Vol.880 (1), p.90-99

2012

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Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?

Toxicology (Amsterdam), 2016-11, Vol.372, p.52-63

2016

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Brief daily episode of normoxia inhibits cardioprotection conferred by chronic continuous hypoxia. Role of oxidative stress and BKCa channels

Current pharmaceutical design, 2013-12, Vol.19 (39), p.6880

2013

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LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study

Biomedical chromatography, 2016-07, Vol.30 (7), p.1083-1091

2016

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Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats

Biological and Pharmaceutical Bulletin, 2009/12/01, Vol.32(12), pp.1978-1985

2009

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An alternative approach to validation of liquid chromatography-mass spectrometry methods for the quantification of endogenous compounds

High-throughput salting-out assisted liquid-liquid extraction using a 3D printed device and its application in the quantification of ibrutinib and its metabolite PCI-45227 in human serum

Synthesis of [13C6]‐ibrutinib

Beyond the Meaning of Zines: A Case Study of the Role of Materiality in four Prague-Based Zine Assemblages

Direct Multi‐Deuterium Labelling of Pirtobrutinib

Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis

Kinetically Guided Neoadjuvant Chemoradiotherapy Based on 5-Fluorouracil in Patients with Locally Advanced Rectal Cancer

Multidrug Resistance-Associated Protein 2 Deficiency Aggravates Estrogen-Induced Impairment of Bile Acid Metabolomics in Rats

Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines

In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spectrometry

Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis

Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver

Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats

Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane

Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro

Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways

Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits

[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study

Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study

HPLC determination of arginases inhibitor N-(ω)-hydroxy-nor-l-arginine using core–shell particle column and LC–MS/MS identification of principal metabolite in rat plasma

Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?

Brief daily episode of normoxia inhibits cardioprotection conferred by chronic continuous hypoxia. Role of oxidative stress and BKCa channels

LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study

Alteration of Methotrexate Biliary and Renal Elimination during Extrahepatic and Intrahepatic Cholestasis in Rats

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