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Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade

Science (American Association for the Advancement of Science), 1999-11, Vol.286 (5443), p.1321-1326

1999

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In vivo ubiquitination and proteasome-mediated degradation of p53

Cancer research (Chicago, Ill.), 1996-06, Vol.56 (11), p.2649-2654

1996

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Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53

Molecular and Cellular Biology, 1993-02, Vol.13 (2), p.775-784

1993

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Cell, 1993-11, Vol.75 (3), p.495-505

1993

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A Family of Proteins Structurally and Functionally Related to the E6-AP Ubiquitin-Protein Ligase

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (7), p.2563-2567

1995

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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

Molecular and Cellular Biology, 1997-01, Vol.17 (1), p.355-363

1997

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The State of the p53 and Retinoblastoma Genes in Human Cervical Carcinoma Cell Lines

Proceedings of the National Academy of Sciences - PNAS, 1991-07, Vol.88 (13), p.5523-5527

1991

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Human papillomavirus immortalization and transformation functions

Virus Research, 2002-11, Vol.89 (2), p.213-228

2002

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Chronic Estrogen-Induced Cervical and Vaginal Squamous Carcinogenesis in Human Papillomavirus Type 16 Transgenic Mice

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (7), p.2930-2935

1996

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Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

Journal of Virology, 1994-07, Vol.68 (7), p.4358-4368

1994

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Mutations in serines 15 and 20 of human p53 impair its apoptotic activity

Oncogene, 1999-05, Vol.18 (21), p.3205-3212

1999

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Adenovirus E1A, Simian Virus 40 Tumor Antigen, and Human Papillomavirus E7 Protein Share the Capacity to Disrupt the Interaction Between Transcription Factor E2F and the Retinoblastoma Gene Product

Proceedings of the National Academy of Sciences - PNAS, 1992-05, Vol.89 (10), p.4549-4553

1992

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Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes

Cell, 2004-04, Vol.117 (3), p.349-360

2004

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The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Journal of Virology, 1989-10, Vol.63 (10), p.4417-4421

1989

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Identification of a Human Ubiquitin-Conjugating Enzyme that Mediates the E6-AP-Dependent Ubiquitination of p53

Proceedings of the National Academy of Sciences - PNAS, 1994-09, Vol.91 (19), p.8797-8801

1994

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Disruption of Either the E1 or the E2 Regulatory Gene of Human Papillomavirus Type 16 Increases Viral Immortalization Capacity

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.3159-3163

1992

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Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

Molecular and Cellular Biology, 1993-08, Vol.13 (8), p.4918-4927

1993

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Efficiency of Binding the Retinoblastoma Protein Correlates with the Transforming Capacity of the E7 Oncoproteins of the Human Papillomaviruses

Proceedings of the National Academy of Sciences - PNAS, 1992-05, Vol.89 (10), p.4442-4446

1992

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Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

Science (American Association for the Advancement of Science), 1990-04, Vol.248 (4951), p.76-79

1990

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Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kinase Inhibitor Activity

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (9), p.4350-4354

1996

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The Human Papilloma Virus--16 E7 Oncoprotein is Able to Bind to the Retinoblastoma Gene Product

Science (American Association for the Advancement of Science), 1989-02, Vol.243 (4893), p.934-937

1989

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Role of the human papillomaviruses in human cancer

Cancer research (Baltimore), 1991-09, Vol.51 (18), p.5019s-5022s

HOWLEY, P. M

1991

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The transcriptional transactivation function of wild‐type p53 is inhibited by SV40 large T‐antigen and by HPV‐16 E6 oncoprotein

The EMBO journal, 1992-12, Vol.11 (13), p.5013-5020

1992

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Suppression of cellular proliferation by the papillomavirus E2 protein

Journal of Virology, 1995-12, Vol.69 (12), p.7791-7799

1995

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A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes

Journal of Virology, 2001-12, Vol.75 (24), p.12347-12358

2001

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Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade

In vivo ubiquitination and proteasome-mediated degradation of p53

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

A Family of Proteins Structurally and Functionally Related to the E6-AP Ubiquitin-Protein Ligase

Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

The State of the p53 and Retinoblastoma Genes in Human Cervical Carcinoma Cell Lines

Human papillomavirus immortalization and transformation functions

Chronic Estrogen-Induced Cervical and Vaginal Squamous Carcinogenesis in Human Papillomavirus Type 16 Transgenic Mice

Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity

Adenovirus E1A, Simian Virus 40 Tumor Antigen, and Human Papillomavirus E7 Protein Share the Capacity to Disrupt the Interaction Between Transcription Factor E2F and the Retinoblastoma Gene Product

Interaction of the Bovine Papillomavirus E2 Protein with Brd4 Tethers the Viral DNA to Host Mitotic Chromosomes

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Identification of a Human Ubiquitin-Conjugating Enzyme that Mediates the E6-AP-Dependent Ubiquitination of p53

Disruption of Either the E1 or the E2 Regulatory Gene of Human Papillomavirus Type 16 Increases Viral Immortalization Capacity

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

Efficiency of Binding the Retinoblastoma Protein Correlates with the Transforming Capacity of the E7 Oncoproteins of the Human Papillomaviruses

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

Inhibition of Cyclin D-CDK4/CDK6 Activity is Associated with an E2F-Mediated Induction of Cyclin Kinase Inhibitor Activity

The Human Papilloma Virus--16 E7 Oncoprotein is Able to Bind to the Retinoblastoma Gene Product

Role of the human papillomaviruses in human cancer

The transcriptional transactivation function of wild‐type p53 is inhibited by SV40 large T‐antigen and by HPV‐16 E6 oncoprotein

Suppression of cellular proliferation by the papillomavirus E2 protein

A Human Herpesvirus 7 Glycoprotein, U21, Diverts Major Histocompatibility Complex Class I Molecules to Lysosomes

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