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Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors

PLoS biology, 2015-07, Vol.13 (7), p.e1002194-e1002194

2015

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Small-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1

ChemMedChem, 2016-04, Vol.11 (8), p.802-813

2016

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Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum

Neuropsychopharmacology (New York, N.Y.), 2018-04, Vol.43 (5), p.964-977

2018

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Probing GPCR Dimerization Using Peptides

Frontiers in endocrinology (Lausanne), 2022-07, Vol.13, p.843770-843770

2022

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Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine

The Journal of neuroscience, 2015-04, Vol.35 (17), p.6639-6653

2015

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Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor

Journal of molecular biology, 2024-08, Vol.436 (16), p.168688, Article 168688

2024

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Design and development of stapled transmembrane peptides that disrupt the activity of G-protein–coupled receptor oligomers

The Journal of biological chemistry, 2019-11, Vol.294 (45), p.16587-16603

2019

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Design and synthesis of threading intercalators to target DNA

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (23), p.6956-6959

2010

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Highlighting the Contributions of Marginalized Chemists in the Chemistry Curriculum

Journal of chemical education, 2024-01, Vol.101 (1), p.24-30

2024

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Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7152-7166

2016

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Unveiling the "Three-Finger Pharmacophore" Required for p53-MDM2 Inhibition by Saturation-Transfer Difference (STD) NMR Initial Growth-Rates Approach

Chemistry : a European journal, 2016-04, Vol.22 (17), p.5858-5862

2016

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Identification of Small-Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia-1 (Mcl-1)

ChemMedChem, 2016-04, Vol.11 (8), p.840-844

2016

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Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy

Organic & biomolecular chemistry, 2013-12, Vol.11 (48), p.8340-8347

2013

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Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (21), p.4878-4880

2015

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Targeting Higher-Order DNA: Beyond the G-Quadruplex

Chembiochem : a European journal of chemical biology, 2009-09, Vol.10 (13), p.2139-2143

2009

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Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C‑Terminal Substitution on Biological Activity

Journal of organic chemistry, 2015-10, Vol.80 (19), p.9454-9467

2015

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Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)

Biochemical and biophysical research communications, 2014-04, Vol.447 (1), p.128-132

2014

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A small molecule that induces assembly of a four way DNA junction at low temperature

Chemical communications (Cambridge, England), 2011-08, Vol.47 (29), p.8262-8264

2011

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A natural product inspired fragment-based approach towards the development of novel anti-bacterial agents

MedChemComm, 2016-01, Vol.7 (7), p.1387-1391

2016

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Synthesis of Small Molecules Targeting Multiple DNA Structures using Click Chemistry

ChemMedChem, 2012-05, Vol.7 (5), p.792-804

2012

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A rapid screen for molecules that form duplex to duplex crosslinks in DNA

Chemical communications (Cambridge, England), 2013-10, Vol.49 (80), p.9113-9115

2013

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Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (20), p.5880-5883

2009

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Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors

Small-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1

Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum

Probing GPCR Dimerization Using Peptides

Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine

Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor

Design and development of stapled transmembrane peptides that disrupt the activity of G-protein–coupled receptor oligomers

Design and synthesis of threading intercalators to target DNA

Highlighting the Contributions of Marginalized Chemists in the Chemistry Curriculum

Design and Characterization of Superpotent Bivalent Ligands Targeting Oxytocin Receptor Dimers via a Channel-Like Structure

Unveiling the "Three-Finger Pharmacophore" Required for p53-MDM2 Inhibition by Saturation-Transfer Difference (STD) NMR Initial Growth-Rates Approach

Modulation of dopamine D 1 receptors via histamine H 3 receptors is a novel therapeutic target for Huntington's disease

Identification of Small-Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia-1 (Mcl-1)

Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin

Targeting Higher-Order DNA: Beyond the G-Quadruplex

Solid-Phase Synthesis of Duocarmycin Analogues and the Effect of C‑Terminal Substitution on Biological Activity

Identification and characterisation of a G-quadruplex forming sequence in the promoter region of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)

A small molecule that induces assembly of a four way DNA junction at low temperature

A natural product inspired fragment-based approach towards the development of novel anti-bacterial agents

Synthesis of Small Molecules Targeting Multiple DNA Structures using Click Chemistry

A rapid screen for molecules that form duplex to duplex crosslinks in DNA

Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry

Modulation of dopamine D.sub.1 receptors via histamine H.sub.3 receptors is a novel therapeutic target for Huntington's disease

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