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Innovations, challenges, and minimal information for standardization of humanized mice

EMBO molecular medicine, 2020-07, Vol.12 (7), p.e8662-n/a

2020

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BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains

Toxicological sciences, 2019-05, Vol.169 (1), p.194-208

2019

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Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods

Frontiers in pharmacology, 2024-08, Vol.15, p.1363139

2024

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Nonclinical evaluation of the potential for mast cell activation by an erythropoietin analog

Toxicology and applied pharmacology, 2015-09, Vol.287 (3), p.246-252

2015

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Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and fibre toxicology, 2017-07, Vol.14 (1), p.25-25, Article 25

2017

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Basal Expression Levels of IFNAR and Jak-STAT Components Are Determinants of Cell-Type-Specific Differences in Cardiac Antiviral Responses

Journal of Virology, 2007-12, Vol.81 (24), p.13668-13680

2007

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New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science

Frontiers in medicine, 2023-01, Vol.9, p.1109541-1109541

2023

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Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD20‐Specific Cytotoxicity Induced by Ofatumumab

Clinical and translational science, 2019-05, Vol.12 (3), p.283-290

2019

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Development and validation of a liquid-chromatography tandem mass spectrometry method to determine in vitro and in vivo histamine release

Journal of pharmaceutical and biomedical analysis, 2015-01, Vol.102, p.494-499

2015

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In vivo assessment of natural killer cell responses during chronic feline immunodeficiency virus infection

PloS one, 2012-05, Vol.7 (5), p.e37606-e37606

2012

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Calibration and Validation of a Mechanistic COVID‐19 Model for Translational Quantitative Systems Pharmacology – A Proof‐of‐Concept Model Development for Remdesivir

Clinical pharmacology and therapeutics, 2022-10, Vol.112 (4), p.882-891

2022

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Evaluation of a TGN1412 analogue using in vitro assays and two immune humanized mouse models

Toxicology and applied pharmacology, 2019-06, Vol.372, p.57-69

2019

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Bone marrow-liver-thymus (BLT) immune humanized mice as a model to predict cytokine release syndrome

Translational research : the journal of laboratory and clinical medicine, 2019-08, Vol.210, p.43-56

2019

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Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats

Retrovirology, 2010-01, Vol.7 (1), p.2-2, Article 2

2010

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The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability

Scientific reports, 2020-02, Vol.10 (1), p.2476, Article 2476

2020

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Oral Immunization with Recombinant Listeria monocytogenes Controls Virus Load after Vaginal Challenge with Feline Immunodeficiency Virus

Journal of Virology, 2004-08, Vol.78 (15), p.8210-8218

2004

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Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD 20‐Specific Cytotoxicity Induced by Ofatumumab

Clinical and translational science, 2019-05, Vol.12 (3), p.283-290

2019

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Mucosal challenge with cell-associated or cell-free feline immunodeficiency virus induces rapid and distinctly different patterns of phenotypic change in the mucosal and systemic immune systems

Immunology, 2007-12, Vol.122 (4), p.571-583

2007

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Toll-like receptor expression in feline lymphoid tissues

Veterinary immunology and immunopathology, 2005-07, Vol.106 (3), p.229-237

2005

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FIV infection induces unique changes in phenotype and cellularity in the medial iliac lymph node and intestinal IEL

AIDS research and human retroviruses, 2007-05, Vol.23 (5), p.720-728

2007

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Hepatic mouse models to assess drug metabolism and hepatoxicity

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018, Vol.WCP2018, p.SY47-3

Howard, Kristina E.

2018

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Methodology for isolation and phenotypic characterization of feline small intestinal leukocytes

Journal of immunological methods, 2005-07, Vol.302 (1), p.36-53

2005

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Outbreak of Opportunistic Ascending Pyelonephritis with Numerous Yeast after Experimental Humanization Surgery in NOD.Cg- Prkdc scid Il2rg tm1Wjl /SzJ and NOD.Cg- Rag1 tm1Mom Il2rg tm1Wjl /SzJ Immunodeficient Mice

Comparative medicine, 2018-10, Vol.68 (5), p.353-359

2018

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Outbreak of Opportunistic Ascending Pyelonephritis with Numerous Yeast after Experimental Humanization Surgery in NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ and NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ Immunodeficient Mice

Comparative medicine, 2018-10, Vol.68 (5), p.353-359

2018

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Transforming growth factor-β response to mycobacterial infection in striped bass Morone saxatilis and hybrid tilapia Oreochromis spp

Veterinary immunology and immunopathology, 2003-10, Vol.95 (3), p.155-163

2003

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Innovations, challenges, and minimal information for standardization of humanized mice

BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains

Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods

Nonclinical evaluation of the potential for mast cell activation by an erythropoietin analog

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Basal Expression Levels of IFNAR and Jak-STAT Components Are Determinants of Cell-Type-Specific Differences in Cardiac Antiviral Responses

New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science

Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD20‐Specific Cytotoxicity Induced by Ofatumumab

Development and validation of a liquid-chromatography tandem mass spectrometry method to determine in vitro and in vivo histamine release

In vivo assessment of natural killer cell responses during chronic feline immunodeficiency virus infection

Calibration and Validation of a Mechanistic COVID‐19 Model for Translational Quantitative Systems Pharmacology – A Proof‐of‐Concept Model Development for Remdesivir

Evaluation of a TGN1412 analogue using in vitro assays and two immune humanized mouse models

Bone marrow-liver-thymus (BLT) immune humanized mice as a model to predict cytokine release syndrome

Acute mucosal pathogenesis of feline immunodeficiency virus is independent of viral dose in vaginally infected cats

The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability

Oral Immunization with Recombinant Listeria monocytogenes Controls Virus Load after Vaginal Challenge with Feline Immunodeficiency Virus

Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD 20‐Specific Cytotoxicity Induced by Ofatumumab

Mucosal challenge with cell-associated or cell-free feline immunodeficiency virus induces rapid and distinctly different patterns of phenotypic change in the mucosal and systemic immune systems

Toll-like receptor expression in feline lymphoid tissues

FIV infection induces unique changes in phenotype and cellularity in the medial iliac lymph node and intestinal IEL

Hepatic mouse models to assess drug metabolism and hepatoxicity

Methodology for isolation and phenotypic characterization of feline small intestinal leukocytes

Outbreak of Opportunistic Ascending Pyelonephritis with Numerous Yeast after Experimental Humanization Surgery in NOD.Cg- Prkdc scid Il2rg tm1Wjl /SzJ and NOD.Cg- Rag1 tm1Mom Il2rg tm1Wjl /SzJ Immunodeficient Mice

Outbreak of Opportunistic Ascending Pyelonephritis with Numerous Yeast after Experimental Humanization Surgery in NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ and NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ Immunodeficient Mice

Transforming growth factor-β response to mycobacterial infection in striped bass Morone saxatilis and hybrid tilapia Oreochromis spp

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