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Structural analysis of leader peptide binding enables leader-free cyanobactin processing

Nature chemical biology, 2015-08, Vol.11 (8), p.558-563

2015

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N‑Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway

Biochemistry (Easton), 2018-12, Vol.57 (50), p.6860-6867

2018

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The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

Nature structural & molecular biology, 2012-08, Vol.19 (8), p.767-772

2012

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The structural biology of patellamide biosynthesis

Current opinion in structural biology, 2014-12, Vol.29, p.112-121

2014

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Structure-Based Design, Synthesis and Bioactivity of a New Anti-TNFα Cyclopeptide

Molecules (Basel, Switzerland), 2020-02, Vol.25 (4), p.922

2020

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Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

Chembiochem : a European journal of chemical biology, 2010-09, Vol.11 (13), p.1803-1815

2010

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An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Angewandte Chemie (International ed.), 2014-12, Vol.53 (51), p.14171-14174

International ed. in English, 2014

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Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Journal of antibiotics, 2017-04, Vol.70 (4), p.448-453

2017

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Peptide Cyclization Catalyzed by Cyanobactin Macrocyclases

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.2012, p.193

Houssen, Wael E

2019

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Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress

Marine drugs, 2014-01, Vol.12 (2), p.700-718

2014

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The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides

Chembiochem : a European journal of chemical biology, 2012-12, Vol.13 (18), p.2683-2689

2012

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Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors

MedChemComm, 2013-10, Vol.4 (10), p.1360-1369

2013

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Chemoenzymatic Late‐Stage Modifications Enable Downstream Click‐Mediated Fluorescent Tagging of Peptides

Angewandte Chemie International Edition, 2023-04, Vol.62 (16), p.e202215979-n/a

International ed. in English, 2023

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SARS‐CoV‐2 Spike Protein‐Derived Cyclic Peptides as Modulators of Spike Interaction with GRP78

Chembiochem : a European journal of chemical biology, 2024-06, Vol.25 (12), p.e202300789-n/a

2024

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Spongionella Secondary Metabolites Regulate Store Operated Calcium Entry Modulating Mitochondrial Functioning in SH-SY5Y Neuroblastoma Cells

Cellular physiology and biochemistry, 2015-01, Vol.37 (2), p.779-792

2015

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Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation

Frontiers in immunology, 2016-10, Vol.7, p.452-452

2016

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Solution Structure of the Leader Sequence of the Patellamide Precursor Peptide, PatE1-34

Chembiochem : a European journal of chemical biology, 2010-09, Vol.11 (13), p.1867-1873

2010

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Biochemical characterization of a cyanobactin arginine- N -prenylase from the autumnalamide biosynthetic pathway

Chemical communications (Cambridge, England), 2022-10, Vol.58 (86), p.12054-12057

2022

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Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor‑1 and Cyclotide Kalata B1

Journal of natural products (Washington, D.C.), 2023-03, Vol.86 (3), p.566-573

2023

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A cell-based assay system for activators of the environmental cell stress response

Analytical biochemistry, 2020-03, Vol.592, p.113583, Article 113583

2020

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Gracilins: Spongionella-derived promising compounds for Alzheimer disease

Neuropharmacology, 2015-06, Vol.93, p.285-293

2015

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Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity

Peptides (New York, N.Y. : 1980), 2024-03, Vol.173, p.171139-171139, Article 171139

2024

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The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction

Angewandte Chemie (International ed.), 2013-12, Vol.52 (52), p.13991-13996

International ed. in English, 2013

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Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment

Journal of natural products (Washington, D.C.), 2011-09, Vol.74 (9), p.1965-1971

2011

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The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion

Bioorganic & medicinal chemistry, 2016-01, Vol.24 (2), p.113-122

2016

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Structural analysis of leader peptide binding enables leader-free cyanobactin processing

N‑Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

The structural biology of patellamide biosynthesis

Structure-Based Design, Synthesis and Bioactivity of a New Anti-TNFα Cyclopeptide

Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Peptide Cyclization Catalyzed by Cyanobactin Macrocyclases

Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress

The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides

Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors

Chemoenzymatic Late‐Stage Modifications Enable Downstream Click‐Mediated Fluorescent Tagging of Peptides

SARS‐CoV‐2 Spike Protein‐Derived Cyclic Peptides as Modulators of Spike Interaction with GRP78

Spongionella Secondary Metabolites Regulate Store Operated Calcium Entry Modulating Mitochondrial Functioning in SH-SY5Y Neuroblastoma Cells

Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation

Solution Structure of the Leader Sequence of the Patellamide Precursor Peptide, PatE1-34

Biochemical characterization of a cyanobactin arginine- N -prenylase from the autumnalamide biosynthetic pathway

Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor‑1 and Cyclotide Kalata B1

A cell-based assay system for activators of the environmental cell stress response

Gracilins: Spongionella-derived promising compounds for Alzheimer disease

Venomous gland transcriptome and venom proteomic analysis of the scorpion Androctonus amoreuxi reveal new peptides with anti-SARS-CoV-2 activity

The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase That Operates with a Defined Order of Reaction

Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment

The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion

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