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Tumor-Associated Neutrophils: New Targets for Cancer Therapy

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (7), p.2411-2416

2011

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Mechanistic links between COPD and lung cancer

Nature reviews. Cancer, 2013-04, Vol.13 (4), p.233

Houghton, A McGarry

2013

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Matrix metalloproteinases in destructive lung disease

Matrix biology, 2015-05, Vol.44-46, p.167-174

McGarry Houghton, A.

2015

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Neutrophils dominate the immune cell composition in non-small cell lung cancer

Nature communications, 2017-02, Vol.8 (1), p.14381-14381, Article 14381

2017

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Lung Cancer Subtypes Generate Unique Immune Responses

The Journal of immunology (1950), 2016-12, Vol.197 (11), p.4493-4503

2016

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Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non-Small Cell Lung Cancer

American journal of respiratory and critical care medicine, 2018-02, Vol.197 (3), p.325-336

2018

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Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils

The Journal of clinical investigation, 2022-11, Vol.132 (22), p.1-15

2022

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Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function

Cancer cell, 2022-04, Vol.40 (4), p.393-409.e9

2022

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The paradox of tumor-associated neutrophils: Fueling tumor growth with cytotoxic substances

Cell cycle (Georgetown, Tex.), 2010-05, Vol.9 (9), p.1732-1737

Houghton, A. McGarry

2010

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MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity

Genes & development, 2020-09, Vol.34 (17-18), p.1210-1226

2020

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Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia

American journal of respiratory and critical care medicine, 2019-07, Vol.200 (1), p.84-97

2019

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Insulin Receptor Substrate Regulation of Phosphoinositide 3-Kinase

Clinical cancer research, 2011-01, Vol.17 (2), p.206-211

2011

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Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study

European radiology, 2019-11, Vol.29 (11), p.6100-6108

2019

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Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

Journal of leukocyte biology, 2015-08, Vol.98 (2), p.143-152

2015

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New Immuno-oncology Targets and Resistance Mechanisms

Current treatment options in oncology, 2022-09, Vol.23 (9), p.1201-1218

2022

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Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC

JCI insight, 2019-12, Vol.4 (24)

2019

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Altered Treg Infiltration after Discoidin Domain Receptor 1 (DDR1) Inhibition and Knockout Promotes Tumor Growth in Lung Adenocarcinoma

Cancers, 2023-12, Vol.15 (24), p.5767

2023

Volltextzugriff (PDF)

IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke

PloS one, 2011-05, Vol.6 (5), p.e20333

2011

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Elastin fragments drive disease progression in a murine model of emphysema

The Journal of clinical investigation, 2006-03, Vol.116 (3), p.753-759

2006

Volltextzugriff (PDF)

CXCR1/2 antagonism inhibits neutrophil function and not recruitment in cancer

Oncoimmunology, 2024-12, Vol.13 (1), p.2384674

2024

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Identification of Novel Low-Density Neutrophil Markers Through Unbiased High-Dimensional Flow Cytometry Screening in Non-Small Cell Lung Cancer Patients

Frontiers in immunology, 2021-08, Vol.12, p.703846

2021

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A case series of morbid COPD exacerbations during immune checkpoint inhibitor therapy in cancer patients

Respiratory medicine case reports, 2021-01, Vol.34, p.101541, Article 101541

2021

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Multi-Omic Biomarkers Improve Indeterminate Pulmonary Nodule Malignancy Risk Assessment

Cancers, 2023-06, Vol.15 (13), p.3418

2023

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Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases

Cancer research (Chicago, Ill.), 2006-06, Vol.66 (12), p.6149-6155

2006

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Tumor-Associated Neutrophils: New Targets for Cancer Therapy

Mechanistic links between COPD and lung cancer

Matrix metalloproteinases in destructive lung disease

Neutrophils dominate the immune cell composition in non-small cell lung cancer

Lung Cancer Subtypes Generate Unique Immune Responses

Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non-Small Cell Lung Cancer

Annexin A2/TLR2/MYD88 pathway induces arginase 1 expression in tumor-associated neutrophils

Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function

The paradox of tumor-associated neutrophils: Fueling tumor growth with cytotoxic substances

MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity

Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia

Insulin Receptor Substrate Regulation of Phosphoinositide 3-Kinase

Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study

Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

New Immuno-oncology Targets and Resistance Mechanisms

Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC

Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness

Altered Treg Infiltration after Discoidin Domain Receptor 1 (DDR1) Inhibition and Knockout Promotes Tumor Growth in Lung Adenocarcinoma

IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke

Elastin fragments drive disease progression in a murine model of emphysema

CXCR1/2 antagonism inhibits neutrophil function and not recruitment in cancer

Identification of Novel Low-Density Neutrophil Markers Through Unbiased High-Dimensional Flow Cytometry Screening in Non-Small Cell Lung Cancer Patients

A case series of morbid COPD exacerbations during immune checkpoint inhibitor therapy in cancer patients

Multi-Omic Biomarkers Improve Indeterminate Pulmonary Nodule Malignancy Risk Assessment

Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases

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