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The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Blood, 2007-01, Vol.109 (1), p.145-154

2007

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N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice

Haematologica (Roma), 2018-11, Vol.103 (11), p.1925-1936

2018

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Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms

Haematologica (Roma), 2018-08, Vol.103 (8), p.1403-1413

2018

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Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

Blood, 2014-06, Vol.123 (26), p.4045-4053

2014

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Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor

Frontiers in immunology, 2020-02, Vol.11, p.138-138

2020

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Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response

Blood, 2009-01, Vol.113 (1), p.193-203

2009

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A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A

Molecular therapy, 2011-04, Vol.19 (4), p.723-730

2011

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Contemporary Influences on the Role of Imams in Britain: A Critical Analysis of Leadership and Professionalisation for the Imamate in 21st Century Britain

Religions (Basel, Switzerland ), 2021-09, Vol.12 (9), p.771

2021

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Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells

Journal of thrombosis and haemostasis, 2022-11, Vol.20 (11), p.2507-2518

2022

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Biological considerations of plasma-derived and recombinant factor VIII immunogenicity

Blood, 2017-06, Vol.129 (24), p.3147-3154

2017

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Mice possess a more limited natural antihuman factor VIII antibody repertoire than humans that is produced disproportionately by marginal zone B cells

Journal of thrombosis and haemostasis, 2024-01, Vol.22 (1), p.76-89

2024

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Transgene-host cell interactions mediate significant influences on the production, stability, and function of recombinant canine FVIII

Molecular therapy. Methods & clinical development, 2015-01, Vol.2, p.15033-15033, Article 15033

2015

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Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

Blood, 2001-01, Vol.97 (1), p.107-113

2001

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Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: similarities with the intron 22 inversion mutation in human hemophilia

Thrombosis and haemostasis, 2002-04, Vol.87 (4), p.659-665

2002

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A Novel Von Willebrand Factor Fragment Acts As a Chaperone to Prolong the Half-Life of Recombinant Human FVIII (Simoctocog Alfa) in Hemophilia a Dogs and FVIII/VWF Double Knockout Mice

Blood, 2017-12, Vol.130, p.178-178

2017

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Transforming Rehabilitation and its impact on a locally-based rehabilitation programme for Black and Minority Ethnic and Muslim offenders

European journal of probation, 2016-08, Vol.8 (2), p.68-81

Hough, Christine Victoria

2016

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To clear or to fear: An innate perspective on factor VIII immunity

Cellular immunology, 2016-03, Vol.301, p.82-89

2016

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Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor

Blood, 2005-02, Vol.105 (4), p.1531-1539

2005

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The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Blood, 2007-01, Vol.109 (1), p.145-154

2007

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A Factor VIII Fusion with an Inactivated FIX Generates a Biologically Active Molecule with Delayed Clearance in a FVIII/VWF Knockout Mouse Model

Blood, 2017-12, Vol.130, p.2344-2344

2017

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Recombinant and plasma-derived factor VIII products induce distinct splenic cytokine microenvironments in hemophilia A mice

Blood, 2009-07, Vol.114 (4), p.871-880

2009

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Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A

Blood, 2016-06, Vol.127 (26), p.3439-3449

2016

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War and peace: Factor VIII and the adaptive immune response

Cellular immunology, 2016-03, Vol.301, p.2-7

2016

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The canine factor VIII cDNA and 5' flanking sequence

Thrombosis and haemostasis, 1998-02, Vol.79 (2), p.317-322

1998

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Differential Glycosylation Between Recombinant Factor VIII Produced in Baby Hamster Kidney and Chinese Hamster Ovary Cells Confers Differences in Immunogenicity in a Humanized Hemophilia Α Mouse Model

Blood, 2016-12, Vol.128 (22), p.326-326

2016

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The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice

Dexamethasone promotes durable factor VIII-specific tolerance in hemophilia A mice via thymic mechanisms

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor

Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response

A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A

Contemporary Influences on the Role of Imams in Britain: A Critical Analysis of Leadership and Professionalisation for the Imamate in 21st Century Britain

Heterogeneity and reciprocity of FVIII and VWF expression, and the response to shear stress in cultured human endothelial cells

Biological considerations of plasma-derived and recombinant factor VIII immunogenicity

Mice possess a more limited natural antihuman factor VIII antibody repertoire than humans that is produced disproportionately by marginal zone B cells

Transgene-host cell interactions mediate significant influences on the production, stability, and function of recombinant canine FVIII

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: similarities with the intron 22 inversion mutation in human hemophilia

A Novel Von Willebrand Factor Fragment Acts As a Chaperone to Prolong the Half-Life of Recombinant Human FVIII (Simoctocog Alfa) in Hemophilia a Dogs and FVIII/VWF Double Knockout Mice

Transforming Rehabilitation and its impact on a locally-based rehabilitation programme for Black and Minority Ethnic and Muslim offenders

To clear or to fear: An innate perspective on factor VIII immunity

Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

A Factor VIII Fusion with an Inactivated FIX Generates a Biologically Active Molecule with Delayed Clearance in a FVIII/VWF Knockout Mouse Model

Recombinant and plasma-derived factor VIII products induce distinct splenic cytokine microenvironments in hemophilia A mice

Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A

War and peace: Factor VIII and the adaptive immune response

The canine factor VIII cDNA and 5' flanking sequence

Differential Glycosylation Between Recombinant Factor VIII Produced in Baby Hamster Kidney and Chinese Hamster Ovary Cells Confers Differences in Immunogenicity in a Humanized Hemophilia Α Mouse Model

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