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A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4402-4413

2017

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Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection

Scientific reports, 2015-10, Vol.5 (1), p.15577-15577, Article 15577

2015

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Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation

Nature communications, 2020-02, Vol.11 (1), p.676-676, Article 676

2020

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A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection

Cell research, 2021-01, Vol.31 (1), p.62-79

2021

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A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection

Cell research, 2020-07, Vol.31 (1), p.62-79

2020

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ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling

eLife, 2019-07, Vol.8

2019

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Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Nature communications, 2017-11, Vol.8 (1), p.1730-11, Article 1730

2017

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Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases

Cellular & molecular immunology, 2021-10, Vol.18 (10), p.2358-2371

2021

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Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state

eLife, 2020-02, Vol.9

2020

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Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel

eLife, 2014-12, Vol.3, p.e03606-e03606

2014

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Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4 + T cells from HIV-1 infection

Cell & bioscience, 2017-09, Vol.7 (1), p.47-47, Article 47

2017

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Transpiration characteristics and environmental controls of orange orchards in the dry-hot valley region of southwest China

Agricultural water management, 2023-10, Vol.288, p.108467, Article 108467

2023

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Editorial: Ion Channels: Therapeutic Targets for Neurological Disease

Frontiers in molecular neuroscience, 2021-11, Vol.14, p.797327-797327

2021

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Ligand activation mechanisms of human KCNQ2 channel

Nature communications, 2023-10, Vol.14 (1), p.6632-6632, Article 6632

2023

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Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells

Cell research, 2021-09, Vol.31 (9), p.998-1010

2021

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Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection

Retrovirology, 2017-11, Vol.14 (1), p.51-51, Article 51

2017

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Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling

PloS one, 2014-03, Vol.9 (3), p.e89975-e89975

2014

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The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5

Frontiers in immunology, 2020-09, Vol.11, p.1926

2020

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A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation

Communications biology, 2020-07, Vol.3 (1), p.385, Article 385

2020

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Correction: Autophagy receptor CCDC50 modulates STING-mediated interferon response in viral infection and autoimmune disease

Cellular & molecular immunology, 2021-12, Vol.18 (12), p.2682-2682

2021

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Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma

Signal transduction and targeted therapy, 2021-07, Vol.6 (1), p.275-275, Article 275

2021

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A Non-canonical VSD-Pore Coupling is Responsible for the AO State of KCNQ1 Channels

Biophysical journal, 2018-02, Vol.114 (3), p.122a-122a

Hou, Panpan

2018

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A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling

Communications biology, 2022-04, Vol.5 (1), p.301-301, Article 301

2022

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TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons

PloS one, 2013-10, Vol.8 (10), p.e78203-e78203

2013

Volltextzugriff (PDF)

Single Channel Recordings Reveal Differential β2 Subunit Modulations Between Mammalian and Drosophila BKCa(β2) Channels

PloS one, 2016-10, Vol.11 (10), p.e0163308-e0163308

2016

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A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220

Genome editing of CXCR4 by CRISPR/cas9 confers cells resistant to HIV-1 infection

Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation

A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection

A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection

ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling

Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening

Autophagy receptor CCDC50 tunes the STING-mediated interferon response in viral infections and autoimmune diseases

Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state

Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel

Genome editing of the HIV co-receptors CCR5 and CXCR4 by CRISPR-Cas9 protects CD4 + T cells from HIV-1 infection

Transpiration characteristics and environmental controls of orange orchards in the dry-hot valley region of southwest China

Editorial: Ion Channels: Therapeutic Targets for Neurological Disease

Ligand activation mechanisms of human KCNQ2 channel

Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells

Genome modification of CXCR4 by Staphylococcus aureus Cas9 renders cells resistance to HIV-1 infection

Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling

The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5

A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation

Correction: Autophagy receptor CCDC50 modulates STING-mediated interferon response in viral infection and autoimmune disease

Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma

A Non-canonical VSD-Pore Coupling is Responsible for the AO State of KCNQ1 Channels

A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling

TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons

Single Channel Recordings Reveal Differential β2 Subunit Modulations Between Mammalian and Drosophila BKCa(β2) Channels

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