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The multifaceted roles of tumor-associated proteases and harnessing their activity for prodrug activation

Biological chemistry, 2019-07, Vol.400 (8), p.965-977

2019

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Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index

Science translational medicine, 2013-10, Vol.5 (207), p.207ra144

2013

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Continuous Imaging of Plasmon Rulers in Live Cells Reveals Early-Stage Caspase-3 Activation at the Single-Molecule Level

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (42), p.17735-17740

2009

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Global identification of peptidase specificity by multiplex substrate profiling

Nature methods, 2012-11, Vol.9 (11), p.1095-1100

2012

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The myosin coiled-coil is a truly elastic protein structure

Nature materials, 2002-12, Vol.1 (4), p.232-235

2002

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Prediction of protease substrates using sequence and structure features

Bioinformatics, 2010-07, Vol.26 (14), p.1714-1722

2010

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Antagonistic Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated Cellular Signaling and Migration

The Journal of biological chemistry, 2010-08, Vol.285 (35), p.26878-26888

2010

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Human and mouse granzyme M display divergent and species-specific substrate specificities

Biochemical journal, 2011-08, Vol.437 (3), p.431-442

2011

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Imaging active urokinase plasminogen activator in prostate cancer

Cancer research (Chicago, Ill.), 2015-04, Vol.75 (7), p.1225-1235

2015

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Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors

Biological chemistry, 2016-09, Vol.397 (9), p.871-881

2016

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Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis

The Prostate, 2012-06, Vol.72 (8), p.846-855

2012

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133 CRISPR/Cas9 gene-edited allogeneic CAR-T cells targeting CD33 show high preclinical efficacy against AML without long-term hematopoietic toxicity

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A143-A143

2021

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Hip Is a Pro-survival Substrate of Granzyme B

The Journal of biological chemistry, 2007-09, Vol.282 (38), p.27865-27874

2007

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Optical Imaging of Cellular Immunotherapy against Prostate Cancer

Molecular imaging, 2009-01, Vol.8 (1), p.15-26

2009

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Dictyostelium myosin bipolar thick filament formation: importance of charge and specific domains of the myosin rod

PLoS biology, 2004-11, Vol.2 (11), p.e356-e356

2004

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Temperature dependence of myosin-II tail fragment assembly

Journal of muscle research and cell motility, 2008-05, Vol.29 (2-5), p.109-118

2008

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367 CRISPR/Cas9 gene-edited, allogeneic anti-CD83 CAR-T cells demonstrate potent activity in GvHD and AML tumor models

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A386-A386

2022

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Correction: Dictyostelium Myosin Bipolar Thick Filament Formation: Importance of Charge and Specific Domains of the Myosin Rod

PLoS biology, 2005-03, Vol.3 (3), p.e119

2005

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Monitoring of Natural Killer Cell Immunotherapy Using Noninvasive Imaging Modalities

Cancer research (Chicago, Ill.), 2010-08, Vol.70 (15), p.6109-6113

2010

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Abstract A203: CD3-EGFR bispecific Probody™ therapeutics induced tumor regressions and increased therapeutic window in preclinical studies

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.A203-A203

2015

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Abstract 4570: Development of a proteolytically activatable EGFR Probody for cancer therapy

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4570-4570

2013

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Monitoring of NK-Cell Immunotherapy using non-invasive Imaging Modalities

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (15), p.6109-6113

2010

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Participation and Representation: Does Risk Acceptance Influence the Decision Making of Political Actors?

Hostetter, Joshua Daniel

2018

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Regulation of myosin II bipolar thick filament assembly

Hostetter, Daniel

2004

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Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type

Journal of Cancer, 2012-01, Vol.3 (1), p.58-66

2012

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The multifaceted roles of tumor-associated proteases and harnessing their activity for prodrug activation

Tumor-specific activation of an EGFR-targeting probody enhances therapeutic index

Continuous Imaging of Plasmon Rulers in Live Cells Reveals Early-Stage Caspase-3 Activation at the Single-Molecule Level

Global identification of peptidase specificity by multiplex substrate profiling

The myosin coiled-coil is a truly elastic protein structure

Prediction of protease substrates using sequence and structure features

Antagonistic Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated Cellular Signaling and Migration

Human and mouse granzyme M display divergent and species-specific substrate specificities

Imaging active urokinase plasminogen activator in prostate cancer

Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors

Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis

133 CRISPR/Cas9 gene-edited allogeneic CAR-T cells targeting CD33 show high preclinical efficacy against AML without long-term hematopoietic toxicity

Hip Is a Pro-survival Substrate of Granzyme B

Optical Imaging of Cellular Immunotherapy against Prostate Cancer

Dictyostelium myosin bipolar thick filament formation: importance of charge and specific domains of the myosin rod

Temperature dependence of myosin-II tail fragment assembly

367 CRISPR/Cas9 gene-edited, allogeneic anti-CD83 CAR-T cells demonstrate potent activity in GvHD and AML tumor models

Correction: Dictyostelium Myosin Bipolar Thick Filament Formation: Importance of Charge and Specific Domains of the Myosin Rod

Monitoring of Natural Killer Cell Immunotherapy Using Noninvasive Imaging Modalities

Abstract A203: CD3-EGFR bispecific Probody™ therapeutics induced tumor regressions and increased therapeutic window in preclinical studies

Abstract 4570: Development of a proteolytically activatable EGFR Probody for cancer therapy

Monitoring of NK-Cell Immunotherapy using non-invasive Imaging Modalities

Participation and Representation: Does Risk Acceptance Influence the Decision Making of Political Actors?

Regulation of myosin II bipolar thick filament assembly

Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type

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