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Structural basis for the inhibition of bacterial multidrug exporters

Nature (London), 2013-08, Vol.500 (7460), p.102-106

2013

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Efficacy of laninamivir octanoate in mice with advanced inflammation stage caused by infection of highly lethal influenza virus

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019-08, Vol.25 (8), p.584-588

2019

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Potent In Vitro Antibacterial Activity of DS-8587, a Novel Broad-Spectrum Quinolone, against Acinetobacter baumannii

Antimicrobial Agents and Chemotherapy, 2013-04, Vol.57 (4), p.1978-1981

2013

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Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.105-116

2001

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In Vitro and In Vivo Antibacterial Activities of DC-159a, a New Fluoroquinolone

Antimicrobial Agents and Chemotherapy, 2008-01, Vol.52 (1), p.65-76

2008

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Characteristics of antibiotic resistance and sequence type of Acinetobacter baumannii clinical isolates in Japan and the antibacterial activity of DS-8587

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014-04, Vol.20 (4), p.256-261

2014

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In vivo antianaerobe activity of DS-8587, a new fluoroquinolone, against Fusobacterium necrophorum in a mouse model

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2017-03, Vol.23 (3), p.131-135

2017

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Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance

Journal of Bacteriology, 2000-06, Vol.182 (11), p.3142-3150

2000

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Anti-multidrug-resistant Acinetobacter baumannii activity of DS-8587: In vitro activity and in vivo efficacy in a murine calf muscle infection model

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2014-05, Vol.20 (5), p.312-316

2014

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Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 1999-06, Vol.43 (6), p.1340-1346

1999

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Brillouin gain spectrum manipulation using multifrequency pump and probe for slope-assisted BOTDA with wider dynamic range

Applied physics express, 2022-02, Vol.15 (2), p.22009

2022

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Requirement of the Pseudomonas aeruginosa tonB Gene for High-Affinity Iron Acquisition and Infection

Infection and Immunity, 2000-08, Vol.68 (8), p.4498-4504

2000

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Brillouin Frequency Shift Estimation for Brillouin Optical Time Domain Analysis Using Brillouin Gain and Loss Spectra With SVC

IEEE sensors journal, 2024-05, Vol.24 (9), p.14261-14269

2024

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Synthesis of a novel inhibitor against MRSA and VRE: Preparation from zerumbone ring opening material showing histidine-kinase inhibition

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.1098-1101

2007

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MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4201-4204

2003

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4205-4208

2003

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Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice

Infection and immunity, 2000-04, Vol.68 (4), p.1834-1839

2000

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Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae

Journal of antimicrobial chemotherapy, 2008-07, Vol.62 (1), p.98-104

2008

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Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa

International journal of antimicrobial agents, 2009-10, Vol.34 (4), p.343-346

2009

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 7: Highly soluble and in vivo active quaternary ammonium analogue D13-9001, a potential preclinical candidate

Bioorganic & medicinal chemistry, 2007-11, Vol.15 (22), p.7087-7097

2007

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STUDY ON EFFECTIVENESS OF WCN FOR TRAFFIC SURVEY IN COMMUNITY ROADS

Journal of Japan Society of Civil Engineers, Ser. D3 (Infrastructure Planning and Management), 2018, Vol.74 (5), p.I_817-I_826

2018

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STUDY ON EFFECTIVENESS OF WCN FOR TRAFFIC SURVEY IN COMMUNITY ROADS

Journal of Japan Society of Civil Engineers, Ser. D3 (Infrastructure Planning and Management), 2018, Vol.74(5), pp.I_817-I_826

2018

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Antimicrobial and rapid bactericidal activities of sitafloxacin and other agents against Streptococcus pyogenes

Japanese journal of antibiotics, 2013-10, Vol.66 (5), p.293-304

2013

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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: Exploration of aromatic substituents

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (24), p.8506-8518

2006

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Bactericidal effect of levofloxacin injection in combination with meropenem against Pseudomonas aeruginosa using an in vitro simulation model with a hollow fiber system

Japanese journal of antibiotics, 2012-12, Vol.65 (6), p.355-363

2012

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Structural basis for the inhibition of bacterial multidrug exporters

Efficacy of laninamivir octanoate in mice with advanced inflammation stage caused by infection of highly lethal influenza virus

Potent In Vitro Antibacterial Activity of DS-8587, a Novel Broad-Spectrum Quinolone, against Acinetobacter baumannii

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in Pseudomonas aeruginosa: Novel Agents for Combination Therapy

In Vitro and In Vivo Antibacterial Activities of DC-159a, a New Fluoroquinolone

Characteristics of antibiotic resistance and sequence type of Acinetobacter baumannii clinical isolates in Japan and the antibacterial activity of DS-8587

In vivo antianaerobe activity of DS-8587, a new fluoroquinolone, against Fusobacterium necrophorum in a mouse model

Interplay between Efflux Pumps May Provide Either Additive or Multiplicative Effects on Drug Resistance

Anti-multidrug-resistant Acinetobacter baumannii activity of DS-8587: In vitro activity and in vivo efficacy in a murine calf muscle infection model

Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in Pseudomonas aeruginosa

Brillouin gain spectrum manipulation using multifrequency pump and probe for slope-assisted BOTDA with wider dynamic range

Requirement of the Pseudomonas aeruginosa tonB Gene for High-Affinity Iron Acquisition and Infection

Brillouin Frequency Shift Estimation for Brillouin Optical Time Domain Analysis Using Brillouin Gain and Loss Spectra With SVC

Synthesis of a novel inhibitor against MRSA and VRE: Preparation from zerumbone ring opening material showing histidine-kinase inhibition

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds

Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice

Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae

Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 7: Highly soluble and in vivo active quaternary ammonium analogue D13-9001, a potential preclinical candidate

STUDY ON EFFECTIVENESS OF WCN FOR TRAFFIC SURVEY IN COMMUNITY ROADS

STUDY ON EFFECTIVENESS OF WCN FOR TRAFFIC SURVEY IN COMMUNITY ROADS

Antimicrobial and rapid bactericidal activities of sitafloxacin and other agents against Streptococcus pyogenes

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: Exploration of aromatic substituents

Bactericidal effect of levofloxacin injection in combination with meropenem against Pseudomonas aeruginosa using an in vitro simulation model with a hollow fiber system

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