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Targeting metabolism to regulate immune responses in autoimmunity and cancer

Nature reviews. Drug discovery, 2019-09, Vol.18 (9), p.669-688

2019

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Regulation of Immune Responses by mTOR

Annual review of immunology, 2012-01, Vol.30 (1), p.39-68

2012

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mTORC1 Signaling Regulates Proinflammatory Macrophage Function and Metabolism

The Journal of immunology (1950), 2021-08, Vol.207 (3), p.913-922

2021

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Something in the Air: Hyperoxic Conditioning of the Tumor Microenvironment for Enhanced Immunotherapy

Cancer cell, 2015-04, Vol.27 (4), p.435-436

2015

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Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2

Journal of Immunology, 2006-07, Vol.177 (2), p.1272-1281

2006

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Validation of the Cough Quality-of-Life Questionnaire in Patients With Idiopathic Pulmonary Fibrosis

Chest, 2013-06, Vol.143 (6), p.1745-1749

2013

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mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages

Cell reports (Cambridge), 2017-09, Vol.20 (10), p.2439-2454

2017

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Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Nature communications, 2019-03, Vol.10 (1), p.1128-1128, Article 1128

2019

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Immune dysregulation as a driver of idiopathic pulmonary fibrosis

The Journal of clinical investigation, 2021-01, Vol.131 (2), p.1-9

2021

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Metabolic variations in normal and fibrotic human laryngotracheal‐derived fibroblasts: A Warburg‐like effect

The Laryngoscope, 2017-03, Vol.127 (3), p.E107-E113

2017

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Source of biomass cooking fuel determines pulmonary response to household air pollution

American journal of respiratory cell and molecular biology, 2014-03, Vol.50 (3), p.538-548

2014

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A mouse model of chronic idiopathic pulmonary fibrosis

Physiological reports, 2014-02, Vol.2 (2), p.e00249-n/a

2014

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Sleep Quality and Health-Related Quality of Life in Idiopathic Pulmonary Fibrosis

Chest, 2008-10, Vol.134 (4), p.693-698

2008

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Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells

PloS one, 2016-09, Vol.11 (9), p.e0163288-e0163288

2016

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Egr3 induces a Th17 response by promoting the development of γδ T cells

PloS one, 2014, Vol.9 (1), p.e87265

2014

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Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

The Journal of clinical investigation, 2020-07, Vol.130 (7), p.3865-3884

2020

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Rheumatoid Arthritis-Associated Interstitial Lung Disease: Diagnostic Dilemma

Pulmonary Medicine, 2011-01, Vol.2011, p.872120-12

2011

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Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis

JCI insight, 2023-06, Vol.8 (11)

2023

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Pulmonary vaccination as a novel treatment for lung fibrosis

PloS one, 2012-02, Vol.7 (2), p.e31299-e31299

2012

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Thalidomide for the treatment of cough in idiopathic pulmonary fibrosis: a randomized trial

Annals of internal medicine, 2012-09, Vol.157 (6), p.398

2012

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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Nature immunology, 2011-04, Vol.12 (4), p.295

2011

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Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1

PloS one, 2012-11, Vol.7 (11), p.e49801-e49801

2012

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Threat matrix: low-molecular-weight hyaluronan (HA) as a danger signal

Immunologic research, 2005-01, Vol.31 (3), p.207-218

2005

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A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells

Blood, 2008-01, Vol.111 (1), p.251-259

2008

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Macrophage monocarboxylate transporter 1 promotes peripheral nerve regeneration after injury in mice

The Journal of clinical investigation, 2021-11, Vol.131 (21)

2021

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Targeting metabolism to regulate immune responses in autoimmunity and cancer

Regulation of Immune Responses by mTOR

mTORC1 Signaling Regulates Proinflammatory Macrophage Function and Metabolism

Something in the Air: Hyperoxic Conditioning of the Tumor Microenvironment for Enhanced Immunotherapy

Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2

Validation of the Cough Quality-of-Life Questionnaire in Patients With Idiopathic Pulmonary Fibrosis

mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Immune dysregulation as a driver of idiopathic pulmonary fibrosis

Metabolic variations in normal and fibrotic human laryngotracheal‐derived fibroblasts: A Warburg‐like effect

Source of biomass cooking fuel determines pulmonary response to household air pollution

A mouse model of chronic idiopathic pulmonary fibrosis

Sleep Quality and Health-Related Quality of Life in Idiopathic Pulmonary Fibrosis

Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells

Egr3 induces a Th17 response by promoting the development of γδ T cells

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

Rheumatoid Arthritis-Associated Interstitial Lung Disease: Diagnostic Dilemma

Sirolimus-eluting airway stent reduces profibrotic Th17 cells and inhibits laryngotracheal stenosis

Pulmonary vaccination as a novel treatment for lung fibrosis

Thalidomide for the treatment of cough in idiopathic pulmonary fibrosis: a randomized trial

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1

Threat matrix: low-molecular-weight hyaluronan (HA) as a danger signal

A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells

Macrophage monocarboxylate transporter 1 promotes peripheral nerve regeneration after injury in mice

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