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Something old, something new: The marriage of PD-1 and IL-2

Immunity (Cambridge, Mass.), 2023-01, Vol.56 (1), p.8-10

2023

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CD36 - the Achilles' heel of T reg cells

Nature immunology, 2020-03, Vol.21 (3), p.251

2020

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The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment

The Journal of experimental medicine, 2017-02, Vol.214 (2), p.381-400

2017

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Intratumoral CD8 + T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

Cancer immunology research, 2018-01, Vol.6 (1), p.14-24

2018

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Back from the dead: TIL apoptosis in cancer immune evasion

British journal of cancer, 2018-02, Vol.118 (3), p.309-311

2018

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Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

Immunity (Cambridge, Mass.), 2023-02, Vol.56 (2), p.386-405.e10

2023

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Tissue Site and the Cancer Immunity Cycle

Trends in cancer, 2019-10, Vol.5 (10), p.593-603

2019

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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114141-114141, Article 114141

2024

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Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Cell stem cell, 2020-04, Vol.26 (4), p.579-592.e6

2020

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Lack of CD8 + T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer

Science immunology, 2021-10, Vol.6 (64), p.eabi8800

2021

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A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Nature biotechnology, 2024-03, Vol.42 (3), p.424-436

2024

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328 Batf3 dendritic cells and 4–1BB/4–1BB ligand axis are required at the effector phase within the tumor microenvironment for anti-PD-L1 efficacy

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A354-A354

2021

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Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2

JCI insight, 2023-10, Vol.8 (19)

2023

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664 Pulmonary priming of tumor-reactive CD8+ T cells by DC1 is impaired by regulatory T cells

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A692-A692

2021

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Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

Journal for immunotherapy of cancer, 2023-06, Vol.11 (6), p.e006533

2023

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A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion

Immunity (Cambridge, Mass.), 2018-07, Vol.49 (1), p.11-13

2018

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Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy

Cancer cell, 2017-05, Vol.31 (5), p.711-723.e4

2017

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183 Overcoming immunotherapy resistance in T cell-inflamed lung cancer

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A197-A197

2020

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Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment

Advances in experimental medicine and biology, 2017, Vol.1036, p.19-31

2017

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Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment

Journal for immunotherapy of cancer, 2014-01, Vol.2 (1), p.3-3

2014

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A depositional model for offshore deposits of the lower Blue Gate Member, Mancos Shale, Uinta Basin, Utah, USA

Sedimentology, 2017-08, Vol.64 (5), p.1402-1438

2017

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517 Splenic tumor-reactive CD8+ T cells are endowed with a unique potential for expansion and are the dominant source of systemic anti-tumor immunity after ICB therapy

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A542-A542

2022

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Green chemistry puts down roots

Nature (London), 1999-08, Vol.400 (6746), p.797-799

Horton, Brendan

1999

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The particulars on peptides

Nature (London), 1996-02, Vol.379 (6564), p.471-472

HORTON>, BRENDAN

1996

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Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.B154-B154

2016

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Something old, something new: The marriage of PD-1 and IL-2

CD36 - the Achilles' heel of T reg cells

The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment

Intratumoral CD8 + T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

Back from the dead: TIL apoptosis in cancer immune evasion

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

Tissue Site and the Cancer Immunity Cycle

Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Lack of CD8 + T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

328 Batf3 dendritic cells and 4–1BB/4–1BB ligand axis are required at the effector phase within the tumor microenvironment for anti-PD-L1 efficacy

Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2

664 Pulmonary priming of tumor-reactive CD8+ T cells by DC1 is impaired by regulatory T cells

Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion

Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy

183 Overcoming immunotherapy resistance in T cell-inflamed lung cancer

Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment

Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment

A depositional model for offshore deposits of the lower Blue Gate Member, Mancos Shale, Uinta Basin, Utah, USA

517 Splenic tumor-reactive CD8+ T cells are endowed with a unique potential for expansion and are the dominant source of systemic anti-tumor immunity after ICB therapy

Green chemistry puts down roots

The particulars on peptides

Abstract B154: Immune surveillance is thwarted by tumor-cell intrinsic β-catenin signaling

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