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Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects

Cell chemical biology, 2019-03, Vol.26 (3), p.366-377.e12

2019

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Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent

Journal of biomedical science, 2021-09, Vol.28 (1), p.1-62, Article 62

2021

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Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice

Frontiers in behavioral neuroscience, 2023-06, Vol.17, p.1202099

2023

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The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination[S]

Journal of lipid research, 2015-04, Vol.56 (4), p.810-820

2015

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Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents

MedChemComm, 2013-07, Vol.4 (7), p.1073-1078

2013

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Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate： Pharmacokinetic application

Journal of pharmaceutical analysis, 2012-12, Vol.2 (6), p.403-411

2012

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One electron oxidation of 3-methylcholanthrene: A chemical model for its mechanism of carcinogenesis

Journal of molecular structure, 2017-06, Vol.1137, p.67-83

2017

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Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-11, Vol.844 (1), p.15-22

2006

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Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691

Journal of natural products (Washington, D.C.), 2015-07, Vol.78 (7), p.1723-1729

2015

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Abstract 2628: Mithramycin analogs with reduced toxicity for EWS-FLI1 targeting

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2628-2628

2015

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OleD Loki as a Catalyst for Hydroxamate Glycosylation

Chembiochem : a European journal of chemical biology, 2020-04, Vol.21 (7), p.952-957

2020

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Frenolicin B targets peroxiredoxin 1 and glutaredoxin 3 to trigger ROS/4E-BPl-mediated antitumor effects

Cell chemical biology, 2019-01, Vol.26 (3), p.366-377.e12

2019

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Enzymatic Methylation and Structure-Activity-Relationship Studies on Polycarcin V, a Gilvocarcin-Type Antitumor Agent

Chembiochem : a European journal of chemical biology, 2014-12, Vol.15 (18), p.2729-2735

2014

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An HPLC assay for the lipophilic camptothecin analog AR-67 carboxylate and lactone in human whole blood

Biomedical chromatography, 2010-10, Vol.24 (10), p.1045-1051

2010

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Metabolic pathways of the camptothecin analog AR-67

Drug metabolism and disposition, 2011-04, Vol.39 (4), p.683

2011

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Carcinogenicity of 1-Hydroxy-3-methylcholanthrene and Its Electrophilic Sulfate Ester 1-Sulfooxy-3-methylcholanthrene in Sprague-Dawley Rats

Biochemical and biophysical research communications, 1998-02, Vol.243 (1), p.30-35

1998

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Abstract C216: Small molecule antitubulin drugs that evade multiple drug resistance mechanisms

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.C216-C216

2011

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9-Sulfooxymethylanthracene Is an Ultimate Electrophilic and Carcinogenic Form of 9-Hydroxymethylanthracene

Biochemical and biophysical research communications, 1998-10, Vol.251 (1), p.239-243

1998

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Validated LCâMS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application

Journal of pharmaceutical analysis, 2012-12, Vol.2 (6), p.403-411

2012

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Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3md00130j

2013-06

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Formation of radical cations in a model for the metabolism of aromatic hydrocarbons

Biochemical and biophysical research communications, 2004-09, Vol.322 (3), p.1018-1023

2004

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Mass spectrometric analysis of 7-sulfoxymethyl-12-methylbenz[a]anthracene and related electrophilic polycyclic aromatic hydrocarbon metabolites

Journal of mass spectrometry., 2004-11, Vol.39 (11), p.1366-1378

2004

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Formation of Benzylic−DNA Adducts Resulting from 7,12-Dimethylbenz[a]anthracene in Vivo

Chemical research in toxicology, 2005-04, Vol.18 (4), p.686-691

2005

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Rapid induction of mammary cancer by repeated subcutaneous injection of the trans-3,4-dihydrodiol of 7,12-dimethylbenz[ a]anthracene in the female Sprague–Dawley rat

Cancer letters, 2005-04, Vol.220 (2), p.155-160

2005

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Comparative Carcinogenicity of Picene and Dibenz[a,h]anthracene in the Rat

Biochemical and biophysical research communications, 2002-01, Vol.290 (1), p.275-279

2002

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Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects

Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent

Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice

The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination[S]

Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents

Validated LC-MS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate： Pharmacokinetic application

One electron oxidation of 3-methylcholanthrene: A chemical model for its mechanism of carcinogenesis

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma

Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691

Abstract 2628: Mithramycin analogs with reduced toxicity for EWS-FLI1 targeting

OleD Loki as a Catalyst for Hydroxamate Glycosylation

Frenolicin B targets peroxiredoxin 1 and glutaredoxin 3 to trigger ROS/4E-BPl-mediated antitumor effects

Enzymatic Methylation and Structure-Activity-Relationship Studies on Polycarcin V, a Gilvocarcin-Type Antitumor Agent

An HPLC assay for the lipophilic camptothecin analog AR-67 carboxylate and lactone in human whole blood

Metabolic pathways of the camptothecin analog AR-67

Carcinogenicity of 1-Hydroxy-3-methylcholanthrene and Its Electrophilic Sulfate Ester 1-Sulfooxy-3-methylcholanthrene in Sprague-Dawley Rats

Abstract C216: Small molecule antitubulin drugs that evade multiple drug resistance mechanisms

9-Sulfooxymethylanthracene Is an Ultimate Electrophilic and Carcinogenic Form of 9-Hydroxymethylanthracene

Validated LCâMS/MS method for simultaneous determination of SIM and its acid form in human plasma and cell lysate: Pharmacokinetic application

Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3md00130j

Formation of radical cations in a model for the metabolism of aromatic hydrocarbons

Mass spectrometric analysis of 7-sulfoxymethyl-12-methylbenz[a]anthracene and related electrophilic polycyclic aromatic hydrocarbon metabolites

Formation of Benzylic−DNA Adducts Resulting from 7,12-Dimethylbenz[a]anthracene in Vivo

Rapid induction of mammary cancer by repeated subcutaneous injection of the trans-3,4-dihydrodiol of 7,12-dimethylbenz[ a]anthracene in the female Sprague–Dawley rat

Comparative Carcinogenicity of Picene and Dibenz[a,h]anthracene in the Rat

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