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Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route

Scientific reports, 2015-11, Vol.5 (1), p.17035, Article 17035

2015

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A novel preparation method for PLGA microspheres using non-halogenated solvents

Journal of controlled release, 2008-08, Vol.129 (3), p.223-227

2008

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Enhancement of nasal absorption of large molecular weight compounds by combination of mucolytic agent and nonionic surfactant

Journal of controlled release, 2006-01, Vol.110 (2), p.347-352

2006

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Absorption enhancement of poorly absorbed hydrophilic compounds from various mucosal sites by combination of mucolytic agent and non-ionic surfactant

International journal of pharmaceutics, 2007-06, Vol.338 (1), p.87-93

2007

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Influence of fillers in powder formulations containing N-acetyl- l-cysteine on nasal peptide absorption

Journal of controlled release, 2007-07, Vol.120 (1), p.88-94

2007

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Applicability of various amphiphilic polymers to the modification of protein release kinetics from biodegradable reservoir-type microspheres

European journal of pharmaceutics and biopharmaceutics, 2001, Vol.51 (1), p.45-53

2001

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Pharmacokinetics and Metabolism of Bisoprolol Enantiomers in Humans

Journal of pharmaceutical sciences, 1998-03, Vol.87 (3), p.289-294

1998

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Anti-tumor effect of intraperitoneal administration of cisplatin-loaded microspheres to human tumor xenografted nude mice

Journal of controlled release, 2002-04, Vol.80 (1-3), p.295-307

2002

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Stereoselective metabolism of bisoprolol enantiomers in dogs and humans

Life sciences (1973), 1998, Vol.63 (13), p.1097-1108

1998

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Improved nasal absorption of salmon calcitonin by powdery formulation with N-acetyl- l-cysteine as a mucolytic agent

Journal of controlled release, 2006-10, Vol.115 (2), p.183-188

2006

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Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant

Journal of controlled release, 2000-12, Vol.69 (3), p.435-444

2000

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Enhancement of intestinal absorption of poorly absorbed hydrophilic compounds by simultaneous use of mucolytic agent and non-ionic surfactant

European journal of pharmaceutics and biopharmaceutics, 2006, Vol.62 (1), p.52-58

2006

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Stereoselective Pharmacokinetics of Bisoprolol After Intravenous and Oral Administration in Beagle Dogs

Journal of pharmaceutical sciences, 1997-05, Vol.86 (5), p.560-564

1997

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Rupture and drug release characteristics of multi-reservoir type microspheres with poly( dl-lactide- co-glycolide) and poly( dl-lactide)

International journal of pharmaceutics, 2006-12, Vol.327 (1), p.110-116

2006

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Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds

International journal of pharmaceutics, 2008-02, Vol.349 (1), p.94-100

2008

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Synergistic absorption enhancement of salmon calcitonin and reversible mucosal injury by applying a mucolytic agent and a non-ionic surfactant

International journal of pharmaceutics, 2006-06, Vol.316 (1), p.124-130

2006

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Preparation of gelatin microparticles by co-lyophilization with poly(ethylene glycol): characterization and application to entrapment into biodegradable microspheres

International journal of pharmaceutics, 2001-05, Vol.219 (1), p.127-137

2001

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Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethylene glycol) aqueous mixture

Pharmaceutical research, 2000-11, Vol.17 (11), p.1367-1373

2000

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Evaluation of in vivo release characteristics of protein-loaded biodegradable microspheres in rats and severe combined immunodeficiency disease mice

Journal of controlled release, 2001-06, Vol.73 (2), p.213-221

2001

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Organ distribution of cisplatin after intraperitoneal administration of cisplatin-loaded microspheres

European journal of pharmaceutics and biopharmaceutics, 2002-07, Vol.54 (1), p.1-7

2002

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A new method of preparing TRH derivative-loaded poly(dl-lactide-coglycolide) microspheres based on a solid solution system

Drug discoveries & therapeutics, 2008-02, Vol.2 (1), p.45-51

2008

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Relation between dissolution profiles and toxicity of cisplatin-loaded microspheres

European journal of pharmaceutics and biopharmaceutics, 2002-03, Vol.53 (2), p.241-247

2002

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Pharmacokinetic behaviour of cisplatin in peritoneal fluid after intraperitoneal administration of cisplatin-loaded microspheres

Journal of pharmacy and pharmacology, 2001-10, Vol.53 (10), p.1331-1339

2001

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Sensitive determination of bisoprolol enantiomers in plasma and urine by high-performance liquid chromatography using fluorescence detection, and application to preliminary study in humans

Journal of chromatography, 1993-09, Vol.619 (2), p.267-273

1993

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HIV感染機構を利用した感染細胞指向性ベクターの開発

ファルマシア, 1998/09/01, Vol.34(9), pp.919-920

堀切, 勇児

1998

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Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route

A novel preparation method for PLGA microspheres using non-halogenated solvents

Enhancement of nasal absorption of large molecular weight compounds by combination of mucolytic agent and nonionic surfactant

Absorption enhancement of poorly absorbed hydrophilic compounds from various mucosal sites by combination of mucolytic agent and non-ionic surfactant

Influence of fillers in powder formulations containing N-acetyl- l-cysteine on nasal peptide absorption

Applicability of various amphiphilic polymers to the modification of protein release kinetics from biodegradable reservoir-type microspheres

Pharmacokinetics and Metabolism of Bisoprolol Enantiomers in Humans

Anti-tumor effect of intraperitoneal administration of cisplatin-loaded microspheres to human tumor xenografted nude mice

Stereoselective metabolism of bisoprolol enantiomers in dogs and humans

Improved nasal absorption of salmon calcitonin by powdery formulation with N-acetyl- l-cysteine as a mucolytic agent

Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant

Enhancement of intestinal absorption of poorly absorbed hydrophilic compounds by simultaneous use of mucolytic agent and non-ionic surfactant

Stereoselective Pharmacokinetics of Bisoprolol After Intravenous and Oral Administration in Beagle Dogs

Rupture and drug release characteristics of multi-reservoir type microspheres with poly( dl-lactide- co-glycolide) and poly( dl-lactide)

Influence of various combinations of mucolytic agent and non-ionic surfactant on intestinal absorption of poorly absorbed hydrophilic compounds

Synergistic absorption enhancement of salmon calcitonin and reversible mucosal injury by applying a mucolytic agent and a non-ionic surfactant

Preparation of gelatin microparticles by co-lyophilization with poly(ethylene glycol): characterization and application to entrapment into biodegradable microspheres

Formation and isolation of spherical fine protein microparticles through lyophilization of protein-poly(ethylene glycol) aqueous mixture

Evaluation of in vivo release characteristics of protein-loaded biodegradable microspheres in rats and severe combined immunodeficiency disease mice

Organ distribution of cisplatin after intraperitoneal administration of cisplatin-loaded microspheres

A new method of preparing TRH derivative-loaded poly(dl-lactide-coglycolide) microspheres based on a solid solution system

Relation between dissolution profiles and toxicity of cisplatin-loaded microspheres

Pharmacokinetic behaviour of cisplatin in peritoneal fluid after intraperitoneal administration of cisplatin-loaded microspheres

Sensitive determination of bisoprolol enantiomers in plasma and urine by high-performance liquid chromatography using fluorescence detection, and application to preliminary study in humans

HIV感染機構を利用した感染細胞指向性ベクターの開発

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