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CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial

BMJ open respiratory research, 2022-01, Vol.9 (1), p.e001060

2022

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Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

Journal of cell science, 2009-01, Vol.122 (2), p.227-232

2009

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Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

American journal of respiratory and critical care medicine, 2008, Vol.177 (1), p.56-65

2008

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Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82-90

2008

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Interleukin-1β Causes Acute Lung Injury via αvβ5 and αvβ6 Integrin–Dependent Mechanisms

Circulation research, 2008-04, Vol.102 (7), p.804-812

2008

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Role of Integrin αvβ6 in Acute Lung Injury Induced by Pseudomonas aeruginosa

Infection and Immunity, 2008-06, Vol.76 (6), p.2325-2332

2008

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αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

The American journal of pathology, 2007, Vol.170 (1), p.110-125

2007

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Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism

Cancer research (Chicago, Ill.), 2008-01, Vol.68 (2), p.561-570

2008

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Normal long bone growth and development in type X collagen-null mice

Nature genetics, 1994-10, Vol.8 (2), p.129-135

1994

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Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Journal of pharmaceutical sciences, 2002-02, Vol.91 (2), p.371-387

2002

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Antibody-Mediated Blockade of Integrin αvβ6Inhibits Tumor Progression In vivo by a Transforming Growth Factor-β-Regulated Mechanism

Cancer research (Chicago, Ill.), 2008-01, Vol.68 (2), p.561-570

2008

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Homeotic Transformation of Cervical Vertebrae in Hoxa-4 Mutant Mice

Proceedings of the National Academy of Sciences - PNAS, 1994-12, Vol.91 (26), p.12644-12648

1994

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Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

Journal of cell science, 2009-01, Vol.122 (Pt 2), p.227-232

2009

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Functional antagonists of sonic hedgehog reveal the importance of the N terminus for activity

Journal of cell science, 1999-12, Vol.112 ( Pt 23) (23), p.4405-4414

1999

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Role of Integrin alpha v beta 6 in Acute Lung Injury Induced by Pseudomonas aeruginosa

Infection and immunity, 2008-06, Vol.76 (6), p.2325-2332

2008

Volltextzugriff (PDF)

Inhibition of Integrin ¿vß6, an Activator of Latent Transforming Growth Factor-ß, Prevents Radiation-induced Lung Fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82

2008

Volltextzugriff (PDF)

Partial Inhibition of Integrin ¿vß6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.56

2008

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Antibody-Mediated Blockade of Integrin alpha sub(v) beta sub(6) Inhibits Tumor Progression In vivo by a Transforming Growth Factor- beta -Regulated Mechanism

Cancer research (Chicago, Ill.), 2008-01, Vol.68 (2), p.561-570

2008

Volltextzugriff (PDF)

Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse

The American journal of pathology, 2007-01, Vol.170 (1), p.110-125

2007

Volltextzugriff (PDF)

Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa

Infection and immunity, 2008-06, Vol.76 (6), p.2325

2008

Volltextzugriff (PDF)

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms

Circulation research, 2008-04, Vol.102 (7), p.804-812

2008

Volltextzugriff (PDF)

Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.56

2008

Volltextzugriff (PDF)

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82

2008

Volltextzugriff (PDF)

Inhibition of Integrin {alpha}v 6, an Activator of Latent Transforming Growth Factor- , Prevents Radiation-induced Lung Fibrosis

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.82

2008

Volltextzugriff (PDF)

Partial Inhibition of Integrin {alpha}v 6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

American journal of respiratory and critical care medicine, 2008-01, Vol.177 (1), p.56

2008

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CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial

Mice that lack activity of αvβ6- and αvβ8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

Interleukin-1β Causes Acute Lung Injury via αvβ5 and αvβ6 Integrin–Dependent Mechanisms

Role of Integrin αvβ6 in Acute Lung Injury Induced by Pseudomonas aeruginosa

αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism

Normal long bone growth and development in type X collagen-null mice

Long‐acting forms of Sonic hedgehog with improved pharmacokinetic and pharmacodynamic properties are efficacious in a nerve injury model

Antibody-Mediated Blockade of Integrin αvβ6Inhibits Tumor Progression In vivo by a Transforming Growth Factor-β-Regulated Mechanism

Homeotic Transformation of Cervical Vertebrae in Hoxa-4 Mutant Mice

Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

Functional antagonists of sonic hedgehog reveal the importance of the N terminus for activity

Role of Integrin alpha v beta 6 in Acute Lung Injury Induced by Pseudomonas aeruginosa

Inhibition of Integrin ¿vß6, an Activator of Latent Transforming Growth Factor-ß, Prevents Radiation-induced Lung Fibrosis

Partial Inhibition of Integrin ¿vß6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

Antibody-Mediated Blockade of Integrin alpha sub(v) beta sub(6) Inhibits Tumor Progression In vivo by a Transforming Growth Factor- beta -Regulated Mechanism

Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse

Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms

Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

Inhibition of Integrin {alpha}v 6, an Activator of Latent Transforming Growth Factor- , Prevents Radiation-induced Lung Fibrosis

Partial Inhibition of Integrin {alpha}v 6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation

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