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Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

Cell, 2001-05, Vol.105 (4), p.473-485

2001

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Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily

Cell, 2000-06, Vol.101 (7), p.789-800

2000

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Molecular basis of human ATM kinase inhibition

Nature structural & molecular biology, 2021-10, Vol.28 (10), p.789-798

2021

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Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

Journal of Bacteriology, 2000-11, Vol.182 (21), p.6036-6041

2000

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Structural Biochemistry of ATP-Driven Dimerization and DNA-Stimulated Activation of SMC ATPases

Current biology, 2004-10, Vol.14 (19), p.1778-1782

2004

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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Nature (London), 2002-08, Vol.418 (6897), p.562-566

2002

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Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

The EMBO journal, 1997-11, Vol.16 (22), p.6626-6635

1997

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Crystal Structure of a Thermostable Type B DNA Polymerase from Thermococcus gorgonarius

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (7), p.3600-3605

1999

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DNA double-strand break repair from head to tail

Current Opinion in Structural Biology, 2002-02, Vol.12 (1), p.115-122

2002

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X-Ray Structure of RLI, an Essential Twin Cassette ABC ATPase Involved in Ribosome Biogenesis and HIV Capsid Assembly

Structure (London), 2005-04, Vol.13 (4), p.649-659

2005

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Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs

Journal of molecular biology, 2006-01, Vol.355 (4), p.675-683

2006

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Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Genes & development, 2016-02, Vol.30 (3), p.337-354

2016

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Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

Immunity (Cambridge, Mass.), 2012-01, Vol.36 (1), p.32-42

2012

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The ternary microplasmin-staphylokinase- microplasmin complex is a proteinase-cofactor- substrate complex in action

Nature structural biology, 1998-10, Vol.5 (10), p.917-923

1998

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Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding

Structure (London), 1999-08, Vol.7 (8), p.989-996

1999

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Energetics of the thrombin-fibrinogen interaction

Biochemistry (Easton), 1992-11, Vol.31 (46), p.11567-11571

1992

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Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair

Cold Spring Harbor Symposia on Quantitative Biology, 2000, Vol.65, p.113-126

2000

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89PPre-clinical evaluation of bifunctional SIRPα-antibody fusion proteins for the treatment of acute myeloid leukemia

Annals of oncology, 2018-12, Vol.29 (suppl_10)

2018

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Pre-clinical evaluation of bifunctional SIRPα-antibody fusion proteins for the treatment of acute myeloid leukemia

Annals of oncology, 2018-12, Vol.29, p.x32-x32

2018

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Structural studies of DNA end detection and resection in homologous recombination

Cold Spring Harbor perspectives in biology, 2014-10, Vol.6 (10), p.a017962-a017962

2014

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Chromosome Cohesion: Closing Time

Current biology, 2003-11, Vol.13 (22), p.R866-R868

Hopfner, Karl-Peter

2003

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P28. Efficient CD19-positive leukaemia cell lysis mediated by a T cell-recruiting triple body a[19-3-19]

Journal for immunotherapy of cancer, 2014-03, Vol.2 (S2), p.P19-P19, Article P19

2014

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P23. Efficient ex vivo lysis of acute myeloid leukaemic (AML) cells mediated by triplebodies with dual-targeting capability in conjunction with natural killer cells as effectors

Journal for immunotherapy of cancer, 2014-03, Vol.2 (S2), p.P14-P14, Article P14

2014

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Symmetry Conditions for Binding Processes

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.2727-2731

1992

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DNA Double-Strand Breaks Come into Focus

Cell, 2009-10, Vol.139 (1), p.25-27

Hopfner, Karl-Peter

2009

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Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily

Molecular basis of human ATM kinase inhibition

Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

Structural Biochemistry of ATP-Driven Dimerization and DNA-Stimulated Activation of SMC ATPases

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

Crystal Structure of a Thermostable Type B DNA Polymerase from Thermococcus gorgonarius

DNA double-strand break repair from head to tail

X-Ray Structure of RLI, an Essential Twin Cassette ABC ATPase Involved in Ribosome Biogenesis and HIV Capsid Assembly

Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

The ternary microplasmin-staphylokinase- microplasmin complex is a proteinase-cofactor- substrate complex in action

Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding

Energetics of the thrombin-fibrinogen interaction

Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair

89PPre-clinical evaluation of bifunctional SIRPα-antibody fusion proteins for the treatment of acute myeloid leukemia

Pre-clinical evaluation of bifunctional SIRPα-antibody fusion proteins for the treatment of acute myeloid leukemia

Structural studies of DNA end detection and resection in homologous recombination

Chromosome Cohesion: Closing Time

P28. Efficient CD19-positive leukaemia cell lysis mediated by a T cell-recruiting triple body a[19-3-19]

P23. Efficient ex vivo lysis of acute myeloid leukaemic (AML) cells mediated by triplebodies with dual-targeting capability in conjunction with natural killer cells as effectors

Symmetry Conditions for Binding Processes

DNA Double-Strand Breaks Come into Focus

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