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An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

PLoS genetics, 2022-06, Vol.18 (6), p.e1010228-e1010228

2022

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Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATPα

Neurobiology of disease, 2017-12, Vol.108, p.238-248

2017

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Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies

Neurobiology of disease, 2020-07, Vol.141, p.104879-104879, Article 104879

2020

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A genome-wide enhancer/suppressor screen for Dube3a interacting genes in Drosophila melanogaster

Scientific reports, 2019-02, Vol.9 (1), p.2382-2382, Article 2382

2019

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A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

eLife, 2020-12, Vol.9

2020

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The Drosophila Gene Sulfateless Modulates Autism-Like Behaviors

Frontiers in genetics, 2019-06, Vol.10, p.574-574

2019

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Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT‐Immortalized Cultured Dental Pulp Stem Cells

Stem cells translational medicine, 2015-08, Vol.4 (8), p.905-912

2015

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An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT1A and Dopamine Pathway Activation as Potential Therapies

Biological psychiatry (1969), 2020-11, Vol.88 (9), p.698-709

2020

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A recurrent de novo missense mutation in UBTF causes developmental neuroregression

Human molecular genetics, 2018-02, Vol.27 (4), p.691-705

2018

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TRPC3 channels critically regulate hippocampal excitability and contextual fear memory

Behavioural brain research, 2015-03, Vol.281, p.69-77

2015

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The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

Epigenetics, 2016-09, Vol.11 (9), p.637-642

2016

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A recurrent de novo missense mutation in UBTF causes developmental neuroregression

Human molecular genetics, 2018-04, Vol.27 (7), p.1310-1310

2018

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Corrigendum to “TRPC3 channels critically regulate hippocampal excitability and contextual fear memory” Behav. Brain Res. 281(March) 2015, 69–77

Behavioural brain research, 2017-08, Vol.332, p.379-379

2017

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Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts

eNeuro, 2018-11, Vol.5 (6), p.ENEURO.0484-18.2018

2018

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Parental and larval exposure to nicotine modulate spontaneous activity as well as cholinergic and GABA receptor expression in adult C. elegans

Neurotoxicology and teratology, 2013-09, Vol.39, p.122-127

2013

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An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

PLoS genetics, 2022-06, Vol.18 (6), p.e1010228

2022

Volltextzugriff (PDF)

An unbiased drug screen for seizure suppressors in Dup15q syndrome reveals 5HT1A and dopamine pathway activation as potential therapies

Biological psychiatry (1969), 2020-04, Vol.88 (9), p.698-709

2020

Volltextzugriff (PDF)

An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT 1A and Dopamine Pathway Activation as Potential Therapies

Biological psychiatry (1969), 2020-11, Vol.88 (9), p.698

2020

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Investigation of Cell-Type-Specific Effects and Synergistic Interactions Between Genes in Duplication 15q Syndrome

Hope, Kevin A

2019

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The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

Epigenetics, 2016, Vol.11 (9), p.637-642

2016

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Efficacy and safety of pembrolizumab for the treatment of advanced biliary cancer: Results from the KEYNOTE‐158 and KEYNOTE‐028 studies

International journal of cancer, 2020-10, Vol.147 (8), p.2190-2198

2020

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Role of nurses in addressing modifiable risk factors for early Alzheimer's disease and mild cognitive impairment

British journal of nursing (Mark Allen Publishing), 2020-04, Vol.29 (8), p.460-469

Hope, Kevin

2020

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The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Nature nanotechnology, 2019-12, Vol.14 (12), p.1084-1087

2019

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Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection

PloS one, 2019-04, Vol.14 (4), p.e0213975

2019

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Nintedanib in Progressive Fibrosing Interstitial Lung Diseases

The New England journal of medicine, 2019-10, Vol.381 (18), p.1718-1727

2019

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An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATPα

Transcriptomic and proteomic profiling of glial versus neuronal Dube3a overexpression reveals common molecular changes in gliopathic epilepsies

A genome-wide enhancer/suppressor screen for Dube3a interacting genes in Drosophila melanogaster

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

The Drosophila Gene Sulfateless Modulates Autism-Like Behaviors

Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT‐Immortalized Cultured Dental Pulp Stem Cells

An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT1A and Dopamine Pathway Activation as Potential Therapies

A recurrent de novo missense mutation in UBTF causes developmental neuroregression

TRPC3 channels critically regulate hippocampal excitability and contextual fear memory

The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

A recurrent de novo missense mutation in UBTF causes developmental neuroregression

Corrigendum to “TRPC3 channels critically regulate hippocampal excitability and contextual fear memory” Behav. Brain Res. 281(March) 2015, 69–77

Cell-Type-Specific Changes in Intrinsic Excitability in the Subiculum following Learning and Exposure to Novel Environmental Contexts

Parental and larval exposure to nicotine modulate spontaneous activity as well as cholinergic and GABA receptor expression in adult C. elegans

An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

An unbiased drug screen for seizure suppressors in Dup15q syndrome reveals 5HT1A and dopamine pathway activation as potential therapies

An Unbiased Drug Screen for Seizure Suppressors in Duplication 15q Syndrome Reveals 5-HT 1A and Dopamine Pathway Activation as Potential Therapies

Investigation of Cell-Type-Specific Effects and Synergistic Interactions Between Genes in Duplication 15q Syndrome

The Drosophila melanogaster homolog of UBE3A is not imprinted in neurons

Efficacy and safety of pembrolizumab for the treatment of advanced biliary cancer: Results from the KEYNOTE‐158 and KEYNOTE‐028 studies

Role of nurses in addressing modifiable risk factors for early Alzheimer's disease and mild cognitive impairment

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection

Nintedanib in Progressive Fibrosing Interstitial Lung Diseases

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