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Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

The AAPS journal, 2011-06, Vol.13 (2), p.143-151

2011

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Conditional Weighted Residuals (CWRES) : A Model Diagnostic for the FOCE Method

Pharmaceutical research, 2007-12, Vol.24 (12), p.2187-2197

2007

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Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies

British journal of clinical pharmacology, 2015-01, Vol.79 (1), p.6-17

2015

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Statistical recommendations for count, binary, and ordinal data in rare disease cross-over trials

Orphanet journal of rare diseases, 2023-12, Vol.18 (1), p.391-391, Article 391

2023

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Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV

CPT: pharmacometrics and systems pharmacology, 2024-02, Vol.13 (2), p.270-280

2024

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Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization

CPT: pharmacometrics and systems pharmacology, 2021-12, Vol.10 (12), p.1452-1465

2021

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Pharmacometrics meets statistics—A synergy for modern drug development

CPT: pharmacometrics and systems pharmacology, 2021-10, Vol.10 (10), p.1134-1149

2021

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A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R

Computer methods and programs in biomedicine, 2016-04, Vol.127, p.83-93

2016

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A Population Pharmacokinetic-Pharmacodynamic Model of Pegfilgrastim

The AAPS journal, 2018-08, Vol.20 (5), p.91-91, Article 91

2018

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Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials

Pharmaceutical research, 2017-05, Vol.34 (5), p.1125-1133

2017

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Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

CPT: pharmacometrics and systems pharmacology, 2024-08, Vol.13 (8), p.1327-1340

2024

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Metaheuristics for pharmacometrics

CPT: pharmacometrics and systems pharmacology, 2021-11, Vol.10 (11), p.1297-1309

2021

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A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 — Estimating occupancy in the absence of a reference region

NeuroImage (Orlando, Fla.), 2013-11, Vol.82, p.160-169

2013

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Establishing the suitability of model‐integrated evidence to demonstrate bioequivalence for long‐acting injectable and implantable drug products: Summary of workshop

CPT: pharmacometrics and systems pharmacology, 2023-05, Vol.12 (5), p.624-630

2023

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Generation and application of avatars in pharmacometric modelling

Journal of pharmacokinetics and pharmacodynamics, 2023-10, Vol.50 (5), p.411-423

2023

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Public Workshop Summary Report on Fiscal Year 2021 Generic Drug Regulatory Science Initiatives: Data Analysis and Model‐Based Bioequivalence

Clinical pharmacology and therapeutics, 2021-11, Vol.110 (5), p.1190-1195

2021

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The Standard Output: A Tool‐Agnostic Modeling Storage Format

CPT: pharmacometrics and systems pharmacology, 2018-09, Vol.7 (9), p.543-546

2018

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The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA

The AAPS journal, 2024-02, Vol.26 (2), p.28-28, Article 28

2024

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Adaptive Optimal Designs for Dose-Finding Studies with Time-to-Event Outcomes

The AAPS journal, 2018-01, Vol.20 (1), p.24-24, Article 24

2018

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Model selection and averaging of nonlinear mixed-effect models for robust phase III dose selection

Journal of pharmacokinetics and pharmacodynamics, 2017-12, Vol.44 (6), p.581-597

2017

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Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling

Pharmaceutical research, 2014-08, Vol.31 (8), p.2152-2165

2014

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Preconditioning of Nonlinear Mixed Effects Models for Stabilisation of Variance-Covariance Matrix Computations

The AAPS journal, 2016-03, Vol.18 (2), p.505-518

2016

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Saddle-Reset for Robust Parameter Estimation and Identifiability Analysis of Nonlinear Mixed Effects Models

The AAPS journal, 2020-07, Vol.22 (4), p.90-90, Article 90

2020

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Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models

The AAPS journal, 2019-09, Vol.21 (5), p.95-95, Article 95

2019

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Implementing Optimal Designs for Dose–Response Studies Through Adaptive Randomization for a Small Population Group

The AAPS journal, 2018-09, Vol.20 (5), p.85-85, Article 85

2018

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Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

Conditional Weighted Residuals (CWRES) : A Model Diagnostic for the FOCE Method

Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies

Statistical recommendations for count, binary, and ordinal data in rare disease cross-over trials

Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV

Tutorial for $DESIGN in NONMEM: Clinical trial evaluation and optimization

Pharmacometrics meets statistics—A synergy for modern drug development

A diagnostic tool for population models using non-compartmental analysis: The ncappc package for R

A Population Pharmacokinetic-Pharmacodynamic Model of Pegfilgrastim

Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials

Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

Metaheuristics for pharmacometrics

A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 — Estimating occupancy in the absence of a reference region

Establishing the suitability of model‐integrated evidence to demonstrate bioequivalence for long‐acting injectable and implantable drug products: Summary of workshop

Generation and application of avatars in pharmacometric modelling

Public Workshop Summary Report on Fiscal Year 2021 Generic Drug Regulatory Science Initiatives: Data Analysis and Model‐Based Bioequivalence

The Standard Output: A Tool‐Agnostic Modeling Storage Format

The Role of Model Master Files for Sharing, Acceptance, and Communication with FDA

Adaptive Optimal Designs for Dose-Finding Studies with Time-to-Event Outcomes

Model selection and averaging of nonlinear mixed-effect models for robust phase III dose selection

Improved Utilization of ADAS-Cog Assessment Data Through Item Response Theory Based Pharmacometric Modeling

Preconditioning of Nonlinear Mixed Effects Models for Stabilisation of Variance-Covariance Matrix Computations

Saddle-Reset for Robust Parameter Estimation and Identifiability Analysis of Nonlinear Mixed Effects Models

Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models

Implementing Optimal Designs for Dose–Response Studies Through Adaptive Randomization for a Small Population Group

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