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Designing and optimizing library selection strategies for generating high-affinity antibodies

Trends in biotechnology (Regular ed.), 1997-02, Vol.15 (2), p.62-70

Hoogenboom, Hennie R.

1997

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By-passing immunization: Human antibodies from V-gene libraries displayed on phage

Journal of molecular biology, 1991-12, Vol.222 (3), p.581-597

1991

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An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line

British journal of cancer, 1999-06, Vol.80 (8), p.1214-1222

1999

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Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen

Bio/technology (New York, N.Y. 1983), 1994-09, Vol.12 (9), p.899-903

1994

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Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning

British journal of cancer, 2000-07, Vol.83 (2), p.252-260

2000

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Design and application of diabodies, triabodies and tetrabodies for cancer targeting

Journal of Immunological Methods, 2001-02, Vol.248 (1), p.47-66

2001

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Molecular evolution of proteins on filamentous phage : mimicking the strategy of the immune system

The Journal of biological chemistry, 1992-08, Vol.267 (23), p.16007-16010

1992

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Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma

Cancer research (Chicago, Ill.), 1998-10, Vol.58 (19), p.4324-4332

1998

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High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting

British journal of cancer, 1998-12, Vol.78 (11), p.1407-1416

1998

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A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18218-18230

1999

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Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma

European journal of cancer (1990), 2001-03, Vol.37 (4), p.542-549

2001

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By-passing immunisation : human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

Journal of molecular biology, 1992-09, Vol.227 (2), p.381-388

1992

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Making Antibodies by Phage Display Technology

Annual review of immunology, 1994-01, Vol.12 (1), p.433-455

1994

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Selecting and screening recombinant antibody libraries

Nature biotechnology, 2005-09, Vol.23 (9), p.1105-1116

Hoogenboom, Hennie R

2005

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Construction and characterization of a bispecific diabody for retargeting T cells to human carcinomas

International journal of cancer, 1998-04, Vol.76 (2), p.232-239

1998

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Multi-subunit proteins on the surface of filamentous phage : methodologies for displaying antibody (Fab) heavy and light chains

Nucleic acids research, 1991-08, Vol.19 (15), p.4133-4137

1991

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Phage diabody repertoires for selection of large numbers of bispecific antibody fragments

Nature biotechnology, 1996-09, Vol.14 (9), p.1149-1154

1996

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Direct Visualization of Distinct T Cell Epitopes Derived from a Melanoma Tumor-Associated Antigen by Using Human Recombinant Antibodies with MHC-Restricted T Cell Receptor-like Specificity

Proceedings of the National Academy of Sciences - PNAS, 2002-07, Vol.99 (14), p.9421-9426

2002

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Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

British journal of cancer, 2002-03, Vol.86 (6), p.954-962

2002

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Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalytic subunit

Cancer research (Chicago, Ill.), 2002-06, Vol.62 (11), p.3184-3194

2002

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Direct Selection of a Human Antibody Fragment Directed against the Tumor T-Cell Epitope HLA-A1-MAGE-A1 from a Nonimmunized Phage-Fab Library

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.7969-7974

2000

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A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

FEBS letters, 1999-12, Vol.463 (1), p.77-82

1999

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Making antibody fragments using phage display libraries

Nature (London), 1991-08, Vol.352 (6336), p.624-628

1991

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Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents

The EMBO journal, 1994-02, Vol.13 (3), p.692-698

1994

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Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments

Gene, 2004-11, Vol.342 (2), p.211-218

2004

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Designing and optimizing library selection strategies for generating high-affinity antibodies

By-passing immunization: Human antibodies from V-gene libraries displayed on phage

An anti-CD30 single-chain Fv selected by phage display and fused to Pseudomonas exotoxin A (Ki-4(scFv)-ETA') is a potent immunotoxin against a Hodgkin-derived cell line

Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen

Human anti-CD30 recombinant antibodies by guided phage antibody selection using cell panning

Design and application of diabodies, triabodies and tetrabodies for cancer targeting

Molecular evolution of proteins on filamentous phage : mimicking the strategy of the immune system

Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting

A Large Non-immunized Human Fab Fragment Phage Library That Permits Rapid Isolation and Kinetic Analysis of High Affinity Antibodies

Identification of colon tumour-associated antigens by phage antibody selections on primary colorectal carcinoma

By-passing immunisation : human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

Making Antibodies by Phage Display Technology

Selecting and screening recombinant antibody libraries

Construction and characterization of a bispecific diabody for retargeting T cells to human carcinomas

Multi-subunit proteins on the surface of filamentous phage : methodologies for displaying antibody (Fab) heavy and light chains

Phage diabody repertoires for selection of large numbers of bispecific antibody fragments

Direct Visualization of Distinct T Cell Epitopes Derived from a Melanoma Tumor-Associated Antigen by Using Human Recombinant Antibodies with MHC-Restricted T Cell Receptor-like Specificity

Selection and characterisation of a phage-displayed human antibody (Fab) reactive to the lung resistance-related major vault protein

Isolation and characterization of human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells directed toward the widely expressed tumor T-cell epitopes of the telomerase catalytic subunit

Direct Selection of a Human Antibody Fragment Directed against the Tumor T-Cell Epitope HLA-A1-MAGE-A1 from a Nonimmunized Phage-Fab Library

A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization

Making antibody fragments using phage display libraries

Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents

Construction and diversification of yeast cell surface displayed libraries by yeast mating: application to the affinity maturation of Fab antibody fragments

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