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Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?

Current medicinal chemistry, 2002-11, Vol.9 (22), p.2055-2075

2002

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DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin

Oncogene, 2012-10, Vol.31 (41), p.4472-4483

2012

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Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells

Diabetologia, 2012-07, Vol.55 (7), p.2005-2015

2012

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Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain

FEBS letters, 2013-11, Vol.587 (23), p.3869-3874

2013

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Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases

The Journal of biological chemistry, 1990-11, Vol.265 (32), p.19401-19404

1990

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Modeling the antiferromagnetic MnIIMnII system within the protein phosphatase-5 catalytic site

Journal of molecular modeling, 2015, Vol.21 (1), p.14-14, Article 14

2015

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Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate

Science (American Association for the Advancement of Science), 1997-10, Vol.278 (5337), p.471-474

1997

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Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A

FEBS letters, 1993-09, Vol.330 (3), p.283-286

Honkanen, Richard E.

1993

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Activation of Protein Kinases and Inhibition of Protein Phosphatases Play a Central Role in the Regulation of Exocytosis in Mouse Pancreatic β Cells

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4343-4347

1994

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Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia

Circulation (New York, N.Y.), 1998-09, Vol.98 (9), p.899-905

1998

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Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A

FEBS letters, 1997-10, Vol.416 (3), p.230-234

1997

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Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain

The Journal of biological chemistry, 1991-04, Vol.266 (10), p.6614-6619

1991

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Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases

Molecular pharmacology, 1991-10, Vol.40 (4), p.577-583

1991

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Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)

The Journal of biological chemistry, 1998-01, Vol.273 (3), p.1462-1468

1998

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Identification of a Functional Link for the p53 Tumor Suppressor Protein in Dexamethasone-induced Growth Suppression

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9747-9753

2003

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Ser/Thr Protein Phosphatase Type 5 (PP5) Is a Negative Regulator of Glucocorticoid Receptor-Mediated Growth Arrest

Biochemistry (Easton), 1999-07, Vol.38 (28), p.8849-8857

1999

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Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest

The Journal of biological chemistry, 1998-05, Vol.273 (20), p.12250

1998

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Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells

Pancreas, 2000-01, Vol.20 (1), p.32-37

2000

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Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: effects of a protein phosphatase inhibitor, fostriecin

Journal of molecular and cellular cardiology, 1997-11, Vol.29 (11), p.3009-3024

1997

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Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice

Cancer letters, 2004-11, Vol.215 (1), p.95-100

2004

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Genomic Organization of the Human PP4 Gene Encoding a Serine/Threonine Protein Phosphatase (PP4) Suggests a Common Ancestry with PP2A

Genomics (San Diego, Calif.), 1997-09, Vol.44 (3), p.336-343

1997

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Importance of the beta 12- beta 13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

The Journal of biological chemistry, 1999-08, Vol.274 (32), p.22366-22372

1999

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Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity

Cancer research (Chicago, Ill.), 1998-08, Vol.58 (16), p.3611-3619

1998

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Identification of an Estrogen-inducible Phosphatase (PP5) That Converts MCF-7 Human Breast Carcinoma Cells into an Estrogen-independent Phenotype when Expressed Constitutively

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27638-27646

2001

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Serine/Threonine Protein Phosphatase Type 1 gamma 1 Is Required for the Completion of Cytokinesis in Human A549 Lung Carcinoma Cells

The Journal of biological chemistry, 2000-01, Vol.275 (3), p.1846-1854

2000

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Regulators of serine/threonine protein phosphatases at the dawn of a clinical era?

DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin

Serine/threonine protein phosphatase 5 regulates glucose homeostasis in vivo and apoptosis signalling in mouse pancreatic islets and clonal MIN6 cells

Genetic disruption of protein phosphatase 5 in mice prevents high-fat diet feeding-induced weight gain

Characterization of microcystin-LR, a potent inhibitor of type 1 and type 2A protein phosphatases

Modeling the antiferromagnetic MnIIMnII system within the protein phosphatase-5 catalytic site

Inhibition of phosphatases and increased Ca2+ channel activity by inositol hexakisphosphate

Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A

Activation of Protein Kinases and Inhibition of Protein Phosphatases Play a Central Role in the Regulation of Exocytosis in Mouse Pancreatic β Cells

Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia

Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A

Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain

Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases

Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)

Identification of a Functional Link for the p53 Tumor Suppressor Protein in Dexamethasone-induced Growth Suppression

Ser/Thr Protein Phosphatase Type 5 (PP5) Is a Negative Regulator of Glucocorticoid Receptor-Mediated Growth Arrest

Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest

Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells

Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: effects of a protein phosphatase inhibitor, fostriecin

Constitutive over expression of serine/threonine protein phosphatase 5 (PP5) augments estrogen-dependent tumor growth in mice

Genomic Organization of the Human PP4 Gene Encoding a Serine/Threonine Protein Phosphatase (PP4) Suggests a Common Ancestry with PP2A

Importance of the beta 12- beta 13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

Fostriecin-mediated G2-M-phase growth arrest correlates with abnormal centrosome replication, the formation of aberrant mitotic spindles, and the inhibition of serine/threonine protein phosphatase activity

Identification of an Estrogen-inducible Phosphatase (PP5) That Converts MCF-7 Human Breast Carcinoma Cells into an Estrogen-independent Phenotype when Expressed Constitutively

Serine/Threonine Protein Phosphatase Type 1 gamma 1 Is Required for the Completion of Cytokinesis in Human A549 Lung Carcinoma Cells

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