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Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies

Drug metabolism and pharmacokinetics, 2022-08, Vol.45, p.100459-100459, Article 100459

2022

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Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin

Biopharmaceutics & drug disposition, 2015-09, Vol.36 (6), p.352-363

2015

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Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells

Molecular cancer therapeutics, 2021-12, Vol.20 (12), p.2329-2340

2021

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Pharmacokinetics and metabolism of mirogabalin, a novel α2δ ligand, in rats and monkeys

Xenobiotica, 2022, Vol.52 (1), p.54-64

2022

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Pharmacokinetics and metabolism of mirogabalin, a novel α 2 δ ligand, in rats and monkeys

Xenobiotica, 2022-01, Vol.52 (1), p.54-64

2022

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Raludotatug Deruxtecan, a CDH6-Targeting Antibody–Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models

Molecular cancer therapeutics, 2024-03, Vol.23 (3), p.257-271

2024

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A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro

Drug metabolism and disposition, 2001-03, Vol.29 (3), p.282

2001

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CYP2D6-Mediated metabolism of a novel acyl coenzyme A:cholesterol acyltransferase inhibitor, pactimibe, and its unique plasma metabolite, R-125528

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.529-534

2008

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Estimation of fraction of drug metabolism by a single UDP‐glucuronosyl transferase enzyme using relative expression factor

Biopharmaceutics & drug disposition, 2022-10, Vol.43 (5), p.213-217

2022

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Abstract 4891: Ifinatamab deruxtecan (I-DXd), a novel B7-H3-targeting antibody-drug conjugate, demonstrates efficient payload delivery into tumor through target-dependent internalization

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.4891-4891

2023

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Pharmacokinetics of DS-5565, a Novel α 2 δ Ligand, in Rats and Monkeys, and Assessment of DDI Risk (P7.313)

Neurology, 2014-04, Vol.82 (10_supplement)

2014

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Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog: Conjugation Reaction of Conjugated Metabolites

Journal of the Mass Spectrometry Society of Japan, 2004, Vol.52(1), pp.21-28

2004

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Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog

Journal of the Mass Spectrometry Society of Japan, 2004-01, Vol.52 (1), p.21

2004

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Metastasis of cervical cancer indicated by elevation of serum CA125 produced by mediastinal lymph nodes: a case report

Journal of medical case reports, 2024-02, Vol.18 (1), p.112-112, Article 112

2024

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Plasma heparin cofactor II activity is inversely associated with albuminuria and its annual deterioration in patients with diabetes

Journal of diabetes investigation, 2021-12, Vol.12 (12), p.2172-2182

2021

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Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Journal of Atherosclerosis and Thrombosis, 2023/08/01, Vol.30(8), pp.871-883

2023

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Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease with a Variety of Visual Symptoms: A Case Report with Autopsy Study

The American journal of case reports, 2023-03, Vol.24, p.e938654-e938654

2023

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Development of Liver Fibrosis Represented by the Fibrosis-4 Index Is a Specific Risk Factor for Tubular Injury in Individuals with Type 2 Diabetes

Biomedicines, 2024-08, Vol.12 (8), p.1789

2024

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Distribution of Extracellular Cellulase Activity in Marine Eukaryotes, Thraustochytrids

Marine biotechnology (New York, N.Y.), 2011-04, Vol.13 (2), p.133-136

2011

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Tubulocystic renal cell carcinoma: a review of literature focused on radiological findings for differential diagnosis

Abdominal radiology (New York), 2018-07, Vol.43 (7), p.1540-1545

2018

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Association of copper transporter expression with platinum resistance in epithelial ovarian cancer

Anticancer research, 2013-04, Vol.33 (4), p.1409-1414

2013

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Claudin-4: a potential therapeutic target in chemotherapy-resistant ovarian cancer

Anticancer research, 2011-04, Vol.31 (4), p.1271-1277

2011

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Clinical Characteristics of Cryopyrin‐Associated Periodic Syndrome and Long‐Term Real‐World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey

Arthritis & rheumatology (Hoboken, N.J.), 2024-06, Vol.76 (6), p.949-962

2024

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Protein Complex of Fibrinogen Gamma Chain and Complement Factor H in Ovarian Cancer Patient Plasma

Anticancer research, 2017-06, Vol.37 (6), p.2861-2866

2017

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Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Journal of Atherosclerosis and Thrombosis, 2023, Vol.30 (8), p.871-883

2023

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Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies

Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin

Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells

Pharmacokinetics and metabolism of mirogabalin, a novel α2δ ligand, in rats and monkeys

Pharmacokinetics and metabolism of mirogabalin, a novel α 2 δ ligand, in rats and monkeys

Raludotatug Deruxtecan, a CDH6-Targeting Antibody–Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models

A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro

CYP2D6-Mediated metabolism of a novel acyl coenzyme A:cholesterol acyltransferase inhibitor, pactimibe, and its unique plasma metabolite, R-125528

Estimation of fraction of drug metabolism by a single UDP‐glucuronosyl transferase enzyme using relative expression factor

Abstract 4891: Ifinatamab deruxtecan (I-DXd), a novel B7-H3-targeting antibody-drug conjugate, demonstrates efficient payload delivery into tumor through target-dependent internalization

Pharmacokinetics of DS-5565, a Novel α 2 δ Ligand, in Rats and Monkeys, and Assessment of DDI Risk (P7.313)

Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog: Conjugation Reaction of Conjugated Metabolites

Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog

Metastasis of cervical cancer indicated by elevation of serum CA125 produced by mediastinal lymph nodes: a case report

Plasma heparin cofactor II activity is inversely associated with albuminuria and its annual deterioration in patients with diabetes

Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease with a Variety of Visual Symptoms: A Case Report with Autopsy Study

Development of Liver Fibrosis Represented by the Fibrosis-4 Index Is a Specific Risk Factor for Tubular Injury in Individuals with Type 2 Diabetes

Distribution of Extracellular Cellulase Activity in Marine Eukaryotes, Thraustochytrids

Tubulocystic renal cell carcinoma: a review of literature focused on radiological findings for differential diagnosis

Association of copper transporter expression with platinum resistance in epithelial ovarian cancer

Claudin-4: a potential therapeutic target in chemotherapy-resistant ovarian cancer

Clinical Characteristics of Cryopyrin‐Associated Periodic Syndrome and Long‐Term Real‐World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey

Protein Complex of Fibrinogen Gamma Chain and Complement Factor H in Ovarian Cancer Patient Plasma

Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

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