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Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization

The Journal of biological chemistry, 2012-09, Vol.287 (38), p.31633-31640

Lee, Hon Cheung

2012

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Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38 + tumors in mouse models in vivo

Scientific reports, 2017-10, Vol.7 (1), p.14289-13, Article 14289

2017

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Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

eLife, 2021-05, Vol.10

2021

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Rational Design and Identification of Small‐Molecule Allosteric Inhibitors of CD38

Chembiochem : a European journal of chemical biology, 2019-10, Vol.20 (19), p.2485-2493

2019

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A cell permeable NPE caged ADP-ribose for studying TRPM2

PloS one, 2012-12, Vol.7 (12), p.e51028-e51028

2012

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Resolving the topological enigma in Ca2+ signaling by cyclic ADP-ribose and NAADP

The Journal of biological chemistry, 2019-12, Vol.294 (52), p.19831-19843

2019

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Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA)

PloS one, 2012-02, Vol.7 (2), p.e31905-e31905

2012

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Crystal Structure of Human CD38 Extracellular Domain

Structure (London), 2005-09, Vol.13 (9), p.1331-1339

2005

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Cyclic ADP ribose is a novel regulator of intracellular Ca2+ oscillations in human bone marrow mesenchymal stem cells

Journal of cellular and molecular medicine, 2011-12, Vol.15 (12), p.2684-2696

2011

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Structure and enzymatic functions of human CD38

Molecular medicine (Cambridge, Mass.), 2006-11, Vol.12 (11-12), p.317-323

Lee, Hon Cheung

2006

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Structural Basis for the Mechanistic Understanding of Human CD38-controlled Multiple Catalysis

The Journal of biological chemistry, 2006-10, Vol.281 (43), p.32861-32869

2006

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Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H)

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.99-108

2017

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The membrane-bound enzyme CD38 exists in two opposing orientations

Science signaling, 2012-09, Vol.5 (241), p.ra67

2012

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Design, Synthesis and Biological Evaluation of Noncovalent Inhibitors of Human CD38 NADase

ChemMedChem, 2012-02, Vol.7 (2), p.223-228

2012

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Structural Basis for Formation and Hydrolysis of the Calcium Messenger Cyclic ADP-ribose by Human CD38

The Journal of biological chemistry, 2007-02, Vol.282 (8), p.5853-5861

2007

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NAADP: a universal Ca2+ trigger

Science signaling, 2008-11, Vol.1 (44), p.re10

2008

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GALA peptide improves the potency of nanobody-drug conjugates by lipid-induced helix formation

Chemical communications (Cambridge, England), 2021-02, Vol.57 (12), p.1434-1437

2021

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Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling

The Journal of biological chemistry, 2005-10, Vol.280 (40), p.33693-33696

Lee, Hon Cheung

2005

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A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1

Nature communications, 2022-12, Vol.13 (1), p.7898-7898, Article 7898

2022

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A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

iScience, 2019-05, Vol.15, p.452-466

2019

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The transferrin receptor CD71 regulates type II CD38, revealing tight topological compartmentalization of intracellular cyclic ADP-ribose production

The Journal of biological chemistry, 2019-10, Vol.294 (42), p.15293-15303

2019

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Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers

Annual review of pharmacology and toxicology, 2001-01, Vol.41 (1), p.317-345

Lee, H C

2001

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ADP-ribosyl Cyclase and CD38 Catalyze the Synthesis of a Calcium-mobilizing Metabolite from NADP+(∗)

The Journal of biological chemistry, 1995-12, Vol.270 (51), p.30327-30333

1995

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Nanobody-based dual epitopes protein identification (DepID) assay for measuring soluble CD38 in plasma of multiple myeloma patients

Analytica chimica acta, 2018-10, Vol.1029, p.65-71

2018

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Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog

The Journal of biological chemistry, 2007-08, Vol.282 (34), p.24825-24832

2007

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Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization

Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38 + tumors in mouse models in vivo

Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

Rational Design and Identification of Small‐Molecule Allosteric Inhibitors of CD38

A cell permeable NPE caged ADP-ribose for studying TRPM2

Resolving the topological enigma in Ca2+ signaling by cyclic ADP-ribose and NAADP

Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA)

Crystal Structure of Human CD38 Extracellular Domain

Cyclic ADP ribose is a novel regulator of intracellular Ca2+ oscillations in human bone marrow mesenchymal stem cells

Structure and enzymatic functions of human CD38

Structural Basis for the Mechanistic Understanding of Human CD38-controlled Multiple Catalysis

Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H)

The membrane-bound enzyme CD38 exists in two opposing orientations

Design, Synthesis and Biological Evaluation of Noncovalent Inhibitors of Human CD38 NADase

Structural Basis for Formation and Hydrolysis of the Calcium Messenger Cyclic ADP-ribose by Human CD38

NAADP: a universal Ca2+ trigger

GALA peptide improves the potency of nanobody-drug conjugates by lipid-induced helix formation

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-mediated Calcium Signaling

A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

The transferrin receptor CD71 regulates type II CD38, revealing tight topological compartmentalization of intracellular cyclic ADP-ribose production

Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers

ADP-ribosyl Cyclase and CD38 Catalyze the Synthesis of a Calcium-mobilizing Metabolite from NADP+(∗)

Nanobody-based dual epitopes protein identification (DepID) assay for measuring soluble CD38 in plasma of multiple myeloma patients

Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog

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