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Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors

Nature communications, 2021-07, Vol.12 (1), p.4578-4578, Article 4578

2021

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Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

Science (American Association for the Advancement of Science), 2008-02, Vol.319 (5866), p.1086-1089

2008

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The impact of cytoskeletal organization on the local regulation of neuronal transport

Nature reviews. Neuroscience, 2017-10, Vol.18 (10), p.585

2017

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Retrograde axonal transport: pathways to cell death?

Trends in neurosciences (Regular ed.), 2010-07, Vol.33 (7), p.335-344

2010

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Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells

Development (Cambridge), 2015-01, Vol.142 (1), p.218-228

2015

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A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner

Nature communications, 2020-11, Vol.11 (1), p.5695-5695, Article 5695

2020

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Autophagosome dynamics in neurodegeneration at a glance

Journal of cell science, 2015-04, Vol.128 (7), p.1259-1267

2015

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An interphase actin wave promotes mitochondrial content mixing and organelle homeostasis

Nature communications, 2024-05, Vol.15 (1), p.3793-3793, Article 3793

2024

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Compartment-Specific Regulation of Autophagy in Primary Neurons

The Journal of neuroscience, 2016-06, Vol.36 (22), p.5933-5945

2016

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Axonal transport: Driving synaptic function

Science (American Association for the Advancement of Science), 2019-10, Vol.366 (6462)

2019

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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.E4439-E4448

2014

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A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

The Journal of neuroscience, 2009-08, Vol.29 (31), p.9903-9917

2009

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The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

The Journal of neuroscience, 2014-01, Vol.34 (4), p.1293-1305

2014

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Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

Developmental cell, 2014-07, Vol.30 (1), p.71-85

2014

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Dynein activators and adaptors at a glance

Journal of cell science, 2019-03, Vol.132 (6)

2019

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Huntingtin facilitates dynein/dynactin-mediated vesicle transport

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (24), p.10045-10050

2007

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Dynein drives nuclear rotation during forward progression of motile fibroblasts

Journal of cell science, 2008-10, Vol.121 (19), p.3187-3195

2008

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Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (12), p.E2466-E2475

2017

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Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

Neuron (Cambridge, Mass.), 2014-10, Vol.84 (2), p.292-309

2014

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ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (24), p.1

2021

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Trim58 Degrades Dynein and Regulates Terminal Erythropoiesis

Developmental cell, 2014-09, Vol.30 (6), p.688-700

2014

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JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

The Journal of cell biology, 2013-08, Vol.202 (3), p.495-508

2013

Volltextzugriff (PDF)

Motor Proteins

Cold Spring Harbor perspectives in biology, 2018-05, Vol.10 (5), p.a021931

2018

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Coordination of molecular motors: from in vitro assays to intracellular dynamics

Current opinion in cell biology, 2010-02, Vol.22 (1), p.4-13

2010

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Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

The Journal of cell biology, 2012-02, Vol.196 (4), p.407-417

2012

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Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors

Differential Regulation of Dynein and Kinesin Motor Proteins by Tau

The impact of cytoskeletal organization on the local regulation of neuronal transport

Retrograde axonal transport: pathways to cell death?

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells

A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner

Autophagosome dynamics in neurodegeneration at a glance

An interphase actin wave promotes mitochondrial content mixing and organelle homeostasis

Compartment-Specific Regulation of Autophagy in Primary Neurons

Axonal transport: Driving synaptic function

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

A Switch in Retrograde Signaling from Survival to Stress in Rapid-Onset Neurodegeneration

The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

Dynein activators and adaptors at a glance

Huntingtin facilitates dynein/dynactin-mediated vesicle transport

Dynein drives nuclear rotation during forward progression of motile fibroblasts

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy

Trim58 Degrades Dynein and Regulates Terminal Erythropoiesis

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

Motor Proteins

Coordination of molecular motors: from in vitro assays to intracellular dynamics

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

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