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Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

PloS one, 2018-08, Vol.13 (8), p.e0201369-e0201369

2018

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A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

Nature medicine, 2018-07, Vol.24 (7), p.1005-1014

2018

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Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival

PloS one, 2007-06, Vol.2 (6), p.e575-e575

2007

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Discovery of XL413, a potent and selective CDC7 inhibitor

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (11), p.3727-3731

2012

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p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells

PLoS biology, 2006-03, Vol.4 (3), p.e51-e51

2006

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High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888

PloS one, 2011-03, Vol.6 (3), p.e17692-e17692

2011

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Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

Nature (London), 2001-02, Vol.409 (6820), p.633-637

2001

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Inactivation of p53 Function in Cultured Human Mammary Epithelial Cells Turns the Telomere-Length Dependent Senescence Barrier from Agonescence into Crisis

Cell cycle (Georgetown, Tex.), 2007-08, Vol.6 (15), p.1927-1936

2007

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Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia

Cancer research (Chicago, Ill.), 2003-04, Vol.63 (7), p.1596-1601

2003

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Correction: High-Content, High-Throughput Analysis of Cell Cycle Perturbations Induced by the HSP90 Inhibitor XL888

PloS one, 2011-03, Vol.6 (3)

2011

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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

Journal of mammary gland biology and neoplasia, 2004-07, Vol.9 (3), p.263-274

2004

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p16INK4a modulates p53 in primary human mammary epithelial cells

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10325-10331

2006

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p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

PLoS biology, 2006-03, Vol.4 (3), p.e51

2006

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Discovery of a novel human anti-IL-2 antibody that potentiates Regulatory T cells by a structure-based mechanism

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.176-176.4

2018

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Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

Journal of mammary gland biology and neoplasia, 2001-04, Vol.6 (2), p.235

2001

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Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase γ Inhibitors

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5467-5482

2012

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p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

PLoS biology, 2006-02, Vol.4 (3), p.e51

2006

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Abstract B160: PWT33597 promotes apoptosis in tumor cells through balanced dual inhibition of PI3K alpha and mTOR

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.B160-B160

2011

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Erratum to “Discovery of XL413, a potent and selective CDC7 inhibitor” [Bioorg. Med. Chem. Lett. 22 (2012) 3727–3731]

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (15), p.5157-5157

2012

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p16 super(INK4a) Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

PLoS biology, 2006-03, Vol.4 (3)

2006

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Characterization of Revertants of unc-93(e1500) in Caenorhabditis elegans Induced by N-ethyl-N-nitrosourea

Genetics (Austin), 1997-10, Vol.147 (2), p.597-608

1997

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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis: Chromosomal instability and breast cancer pathogenesis

Journal of mammary gland biology and neoplasia, 2004, Vol.9 (3), p.263-274

2004

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Genetic and epigenetic modulation of p16INK4A activity in human mammary epithelial cells provides insights into early events in breast cancer

Holst, Charles Ray

2003

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Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival

Bi-allelic CCDC47 Variants Cause a Disorder Characterized by Woolly Hair, Liver Dysfunction, Dysmorphic Features, and Global Developmental Delay

Discovery of XL413, a potent and selective CDC7 inhibitor

p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells

High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

Inactivation of p53 Function in Cultured Human Mammary Epithelial Cells Turns the Telomere-Length Dependent Senescence Barrier from Agonescence into Crisis

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia

Correction: High-Content, High-Throughput Analysis of Cell Cycle Perturbations Induced by the HSP90 Inhibitor XL888

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

p16INK4a modulates p53 in primary human mammary epithelial cells

p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Discovery of a novel human anti-IL-2 antibody that potentiates Regulatory T cells by a structure-based mechanism

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase γ Inhibitors

p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Abstract B160: PWT33597 promotes apoptosis in tumor cells through balanced dual inhibition of PI3K alpha and mTOR

Erratum to “Discovery of XL413, a potent and selective CDC7 inhibitor” [Bioorg. Med. Chem. Lett. 22 (2012) 3727–3731]

p16 super(INK4a) Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Characterization of Revertants of unc-93(e1500) in Caenorhabditis elegans Induced by N-ethyl-N-nitrosourea

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis: Chromosomal instability and breast cancer pathogenesis

Genetic and epigenetic modulation of p16INK4A activity in human mammary epithelial cells provides insights into early events in breast cancer

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