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Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats

Pharmacological research, 2016-11, Vol.113 (Pt A), p.62-70

2016

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Absorption, distribution, metabolism and excretion of peginesatide, a novel erythropoiesis-stimulating agent, in rats

Xenobiotica, 2012-07, Vol.42 (7), p.660-670

2012

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Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia

Experimental hematology, 2006-10, Vol.34 (10), p.1303-1311

2006

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Allosteric Activation of the Follicle-stimulating Hormone (FSH) Receptor by Selective, Nonpeptide Agonists

The Journal of biological chemistry, 2006-05, Vol.281 (19), p.13226-13233

2006

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Reagents for Combinatorial Organic Synthesis: Development of a New o-Nitrobenzyl Photolabile Linker for Solid Phase Synthesis

Journal of organic chemistry, 1995-04, Vol.60 (8), p.2318-2319

1995

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Traceless Solid-Phase Synthesis of Substituted Benzimidazoles via a Base-Cleavable Linker

Organic letters, 2001-01, Vol.3 (1), p.83-86

2001

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Model Studies for New o-Nitrobenzyl Photolabile Linkers: Substituent Effects on the Rates of Photochemical Cleavage

Journal of organic chemistry, 1997-04, Vol.62 (8), p.2370-2380

Holmes, Christopher P

1997

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Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4336-4341

2005

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Discovery and Optimization of a TRAIL R2 Agonist for Cancer Therapy

Advances in experimental medicine and biology, 2009, Vol.611, p.101-103

2009

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A Peroxisome Proliferator-Activated Receptor γ Ligand Inhibits Adipocyte Differentiation

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (11), p.6102-6106

1999

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Differing pharmacological activities of thiazolidinone analogs at the FSH receptor

Biochemical and biophysical research communications, 2008-04, Vol.368 (3), p.723-728

2008

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Multiplexed biochemical assays with biological chips

Nature (London), 1993-08, Vol.364 (6437), p.555-556

1993

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Designing better coumarin-based fluorogenic substrates for PTP1B

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3382-3385

2008

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Novel α,α-Difluorohomophthalimides via Copper-Catalyzed Tandom Cross-Coupling−Cyclization of 2-Halobenzamides with α,α-Difluoro Reformatskii Reagent

Journal of organic chemistry, 2005-06, Vol.70 (12), p.4897-4900

2005

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α,α-Difluoro-β-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4301-4306

2004

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A Traceless Perfluoroalkylsulfonyl (PFS) Linker for the Deoxygenation of Phenols

Organic letters, 2001-08, Vol.3 (17), p.2769-2771

2001

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PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (8), p.2719-2724

2008

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Use of a Perfluoroalkylsulfonyl (PFS) Linker in a "Traceless" Synthesis of Biaryls through Suzuki Cleavage

Angewandte Chemie International Edition, 2001-12, Vol.40 (23), p.4488-4491

2001

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Strategies for Combinatorial Organic Synthesis: Solution and Polymer-Supported Synthesis of 4-Thiazolidinones and 4-Metathiazanones Derived from Amino Acids

Journal of organic chemistry, 1995-11, Vol.60 (22), p.7328-7333

1995

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Methods for the stereoselective synthesis of 2-fluoroalkenoates. Carbonyl condensation reactions of 3,3-bis(methylthio)-2-fluoropropenal, a highly-functionalized fluoroacrylate cation equivalent

Journal of organic chemistry, 1993-10, Vol.58 (21), p.5683-5689

1993

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High-affinity FGFR2 Binding Peptides Derived from the Native Epitope of the KGF Ligand

Advances in experimental medicine and biology, 2009, Vol.611, p.511-512

2009

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Versatile Approach To Encoding Combinatorial Organic Syntheses Using Chemically Robust Secondary Amine Tags

Journal of medicinal chemistry, 1996-04, Vol.39 (8), p.1601-1608

1996

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Spatially-Addressable Immobilization of Macromolecules on Solid Supports

Journal of the American Chemical Society, 1995-12, Vol.117 (49), p.12050-12057

1995

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The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries

Bioorganic & medicinal chemistry letters, 1996-03, Vol.6 (6), p.707-712

1996

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The Traceless Solid-Phase Synthesis of Organic Molecules

Methods in Enzymology, 2003, Vol.369, p.164-182

2003

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Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats

Absorption, distribution, metabolism and excretion of peginesatide, a novel erythropoiesis-stimulating agent, in rats

Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia

Allosteric Activation of the Follicle-stimulating Hormone (FSH) Receptor by Selective, Nonpeptide Agonists

Reagents for Combinatorial Organic Synthesis: Development of a New o-Nitrobenzyl Photolabile Linker for Solid Phase Synthesis

Traceless Solid-Phase Synthesis of Substituted Benzimidazoles via a Base-Cleavable Linker

Model Studies for New o-Nitrobenzyl Photolabile Linkers: Substituent Effects on the Rates of Photochemical Cleavage

Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors

Discovery and Optimization of a TRAIL R2 Agonist for Cancer Therapy

A Peroxisome Proliferator-Activated Receptor γ Ligand Inhibits Adipocyte Differentiation

Differing pharmacological activities of thiazolidinone analogs at the FSH receptor

Multiplexed biochemical assays with biological chips

Designing better coumarin-based fluorogenic substrates for PTP1B

Novel α,α-Difluorohomophthalimides via Copper-Catalyzed Tandom Cross-Coupling−Cyclization of 2-Halobenzamides with α,α-Difluoro Reformatskii Reagent

α,α-Difluoro-β-ketophosphonates as potent inhibitors of protein tyrosine phosphatase 1B

A Traceless Perfluoroalkylsulfonyl (PFS) Linker for the Deoxygenation of Phenols

PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold

Use of a Perfluoroalkylsulfonyl (PFS) Linker in a "Traceless" Synthesis of Biaryls through Suzuki Cleavage

Strategies for Combinatorial Organic Synthesis: Solution and Polymer-Supported Synthesis of 4-Thiazolidinones and 4-Metathiazanones Derived from Amino Acids

Methods for the stereoselective synthesis of 2-fluoroalkenoates. Carbonyl condensation reactions of 3,3-bis(methylthio)-2-fluoropropenal, a highly-functionalized fluoroacrylate cation equivalent

High-affinity FGFR2 Binding Peptides Derived from the Native Epitope of the KGF Ligand

Versatile Approach To Encoding Combinatorial Organic Syntheses Using Chemically Robust Secondary Amine Tags

Spatially-Addressable Immobilization of Macromolecules on Solid Supports

The identification of cyclooxygenase-1 inhibitors from 4-thiazolidinone combinatorial libraries

The Traceless Solid-Phase Synthesis of Organic Molecules

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