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Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5866-5871

2014

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DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

Nature communications, 2023-01, Vol.14 (1), p.432-18, Article 432

2023

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Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

Science (American Association for the Advancement of Science), 2013-12, Vol.342 (6164), p.1385-1389

2013

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Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.5165-5170

2015

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Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1

Proceedings of the National Academy of Sciences - PNAS, 2016-12, Vol.113 (51), p.14727-14732

2016

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Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

PLoS neglected tropical diseases, 2015-10, Vol.9 (10), p.e0004132-e0004132

2015

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An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans

PLoS neglected tropical diseases, 2020-08, Vol.14 (8), p.e0008517

2020

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Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1

Nucleic acids research, 2014-09, Vol.42 (16), p.10845-10855

2014

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Immature Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Experimental biology and medicine (Maywood, N.J.), 2009-10, Vol.234 (10), p.1140-1154

2009

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Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

International journal for parasitology -- drugs and drug resistance, 2020-08, Vol.13, p.8-15

2020

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Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A

Archives of biochemistry and biophysics, 2009-12, Vol.492 (1), p.40-47

2009

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Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

The Journal of biological chemistry, 2008-06, Vol.283 (23), p.16169-16177

2008

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Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection

Cell, 2018-02, Vol.172 (5), p.952-965.e18

2018

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Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

The Journal of biological chemistry, 2023-09, Vol.299 (9), p.105100, Article 105100

2023

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Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product

Biochemistry (Easton), 2022-12, Vol.61 (24), p.2933-2939

2022

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Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase

The Journal of biological chemistry, 2015-01, Vol.290 (4), p.2405-2418

2015

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Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment

PLoS pathogens, 2019-10, Vol.15 (10), p.e1007881

2019

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Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1

RNA (Cambridge), 2022-07, Vol.28 (7), p.927-936

2022

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A pH Switch Controls Zinc Binding in Tomato Copper–Zinc Superoxide Dismutase

Biochemistry (Easton), 2021-05, Vol.60 (20), p.1597-1608

2021

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Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

The Journal of biological chemistry, 2017-07, Vol.292 (27), p.11154-11164

2017

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Structure of the Chlamydia trachomatis Immunodominant Antigen Pgp3

The Journal of biological chemistry, 2013-07, Vol.288 (30), p.22068-22079

2013

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The 1H, 15N and 13C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Biomolecular NMR assignments, 2022-04, Vol.16 (1), p.67-73

2022

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Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population

International journal for parasitology, 2016-06, Vol.46 (7), p.417-424

2016

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The Schizosaccharomyces pombe Pccs Protein Functions in Both Copper Trafficking and Metal Detoxification Pathways

The Journal of biological chemistry, 2004-07, Vol.279 (27), p.28744-28755

2004

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Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q

Biochemistry (Easton), 2009-04, Vol.48 (15), p.3436-3447

2009

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Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense

DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation

Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans

Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1

Immature Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A

Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection

Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product

Insights into the Role of the Unusual Disulfide Bond in Copper-Zinc Superoxide Dismutase

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment

Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1

A pH Switch Controls Zinc Binding in Tomato Copper–Zinc Superoxide Dismutase

Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

Structure of the Chlamydia trachomatis Immunodominant Antigen Pgp3

The 1H, 15N and 13C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population

The Schizosaccharomyces pombe Pccs Protein Functions in Both Copper Trafficking and Metal Detoxification Pathways

Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q

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