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Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations

Diabetologia, 1999-01, Vol.42 (1), p.45-50

1999

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Synthesis of Novel Phenserine-Based-Selective Inhibitors of Butyrylcholinesterase for Alzheimer's Disease

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1855-1861

1999

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Methyl Analogues of the Experimental Alzheimer Drug Phenserine: Synthesis and Structure/Activity Relationships for Acetyl- and Butyrylcholinesterase Inhibitory Action

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4062-4071

2001

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A new therapeutic target in Alzheimer's disease treatment: Attention to butyrylcholinesterase

Current medical research and opinion, 2001-01, Vol.17 (3), p.159-165

2001

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Inhibition of Human Acetyl- and Butyrylcholinesterase by Novel Carbamates of (−)- and (+)-Tetrahydrofurobenzofuran and Methanobenzodioxepine

Journal of medicinal chemistry, 2006-04, Vol.49 (7), p.2174-2185

2006

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Time Course of Pharmacodynamic and Pharmacokinetic Effects of Physostigmine Assessed by Functional Brain Imaging in Humans

Pharmacology, biochemistry and behavior, 2000-07, Vol.66 (3), p.475-481

2000

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Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats

Endocrinology (Philadelphia), 2000-06, Vol.141 (6), p.1936

2000

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The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics

Acta neurologica Scandinavica, 2000-12, Vol.102 (s176), p.74-84

2000

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Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.1919-1929

2005

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Total Syntheses and Anticholinesterase Activities of (3aS)-N(8)-Norphysostigmine, (3aS)-N(8)-Norphenserine, Their Antipodal Isomers, and Other N(8)-Substituted Analogues

Journal of medicinal chemistry, 1997-08, Vol.40 (18), p.2895-2901

1997

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Clinical pharmacokinetics of arecoline in subjects with Alzheimer's disease

Clinical pharmacology and therapeutics, 1996-09, Vol.60 (3), p.276-282

1996

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Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats

The Journal of clinical investigation, 1997-06, Vol.99 (12), p.2883-2889

1997

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Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease

Clinical chemistry (Baltimore, Md.), 1996-02, Vol.42 (2), p.298-302

1996

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The Effects of GLP-1 on Insulin Release in Young and Old Rats in the Fasting State and During an Intravenous Glucose Tolerance Test

The journals of gerontology. Series A, Biological sciences and medical sciences, 1997-09, Vol.52A (5), p.B245-B249

1997

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The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats

Life sciences (1973), 2005-01, Vol.76 (10), p.1073-1081

2005

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Selective Butyrylcholinesterase Inhibition Elevates Brain Acetylcholine, Augments Learning and Lowers Alzheimer β-Amyloid Peptide in Rodent

Proceedings of the National Academy of Sciences - PNAS, 2005-11, Vol.102 (47), p.17213-17218

2005

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Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases

Acta neurobiologiae experimentalis, 2004-01, Vol.64 (1), p.1-9

2004

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Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus

Brain research, 1992-07, Vol.586 (2), p.256-264

1992

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Cerebral glucose utilization in rats is not altered by hindlimb restraint or by femoral artery and vein cannulation

Journal of cerebral blood flow and metabolism, 1988-10, Vol.8 (5), p.720-726

1988

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Delivery of human interferon-alpha to brain by transient osmotic blood-brain barrier modification in the rat

The Journal of pharmacology and experimental therapeutics, 1988-05, Vol.245 (2), p.581

1988

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Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent

Endocrinology (Philadelphia), 2001-10, Vol.142 (10), p.4462

2001

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Regional brain metabolic responsivity to the muscarinic cholinergic agonist arecoline is similar in young and aged Fischer-344 rats

Brain research, 1989-05, Vol.487 (2), p.255-266

1989

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Mohs micrographic surgery: a technique for total margin assessment in veterinary cutaneous oncologic surgery

Veterinary & comparative oncology, 2006-09, Vol.4 (3), p.151-160

2006

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Arecoline-induced elevations of regional cerebral metabolism in the conscious rat

Brain research, 1985-11, Vol.347 (2), p.205-216

1985

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Methiothepin reduces glucose utilization in forebrain regions of awake rats

Psychopharmacologia, 1987-01, Vol.93 (4), p.449-456

1987

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Once daily injection of exendin-4 to diabetic mice achieves long-term beneficial effects on blood glucose concentrations

Synthesis of Novel Phenserine-Based-Selective Inhibitors of Butyrylcholinesterase for Alzheimer's Disease

Methyl Analogues of the Experimental Alzheimer Drug Phenserine: Synthesis and Structure/Activity Relationships for Acetyl- and Butyrylcholinesterase Inhibitory Action

A new therapeutic target in Alzheimer's disease treatment: Attention to butyrylcholinesterase

Inhibition of Human Acetyl- and Butyrylcholinesterase by Novel Carbamates of (−)- and (+)-Tetrahydrofurobenzofuran and Methanobenzodioxepine

Time Course of Pharmacodynamic and Pharmacokinetic Effects of Physostigmine Assessed by Functional Brain Imaging in Humans

Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats

The experimental Alzheimer drug phenserine: preclinical pharmacokinetics and pharmacodynamics

Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors

Total Syntheses and Anticholinesterase Activities of (3aS)-N(8)-Norphysostigmine, (3aS)-N(8)-Norphenserine, Their Antipodal Isomers, and Other N(8)-Substituted Analogues

Clinical pharmacokinetics of arecoline in subjects with Alzheimer's disease

Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats

Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease

The Effects of GLP-1 on Insulin Release in Young and Old Rats in the Fasting State and During an Intravenous Glucose Tolerance Test

The cholinesterase inhibitor, phenserine, improves Morris water maze performance of scopolamine-treated rats

Selective Butyrylcholinesterase Inhibition Elevates Brain Acetylcholine, Augments Learning and Lowers Alzheimer β-Amyloid Peptide in Rodent

Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases

Adrenalectomy or metyrapone-pretreatment abolishes cerebral metabolic responses to the serotonin agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the hippocampus

Cerebral glucose utilization in rats is not altered by hindlimb restraint or by femoral artery and vein cannulation

Delivery of human interferon-alpha to brain by transient osmotic blood-brain barrier modification in the rat

Insertion of an N-terminal 6-aminohexanoic acid after the 7 amino acid position of glucagon-like peptide-1 produces a long-acting hypoglycemic agent

Regional brain metabolic responsivity to the muscarinic cholinergic agonist arecoline is similar in young and aged Fischer-344 rats

Mohs micrographic surgery: a technique for total margin assessment in veterinary cutaneous oncologic surgery

Arecoline-induced elevations of regional cerebral metabolism in the conscious rat

Methiothepin reduces glucose utilization in forebrain regions of awake rats

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