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DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

Scientific reports, 2023-04, Vol.13 (1), p.5964-5964, Article 5964

2023

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3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor

Journal of translational medicine, 2022-08, Vol.20 (1), p.1-375, Article 375

2022

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Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma

PloS one, 2012-08, Vol.7 (8), p.e41401

2012

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Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells

PloS one, 2018-06, Vol.13 (6), p.e0199361-e0199361

2018

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A spontaneously metastatic model of bladder cancer: imaging characterization

Journal of translational medicine, 2019-12, Vol.17 (1), p.425-425, Article 425

2019

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Bioorganic & medicinal chemistry, 2004-07, Vol.12 (14), p.3871-3883

2004

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Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts

BMC biotechnology, 2011-12, Vol.11 (1), p.124-124, Article 124

2011

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Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity

Bioorganic & medicinal chemistry, 2009-01, Vol.17 (2), p.741-751

2009

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Antitumor Efficacy Testing in Rodents

JNCI : Journal of the National Cancer Institute, 2008-11, Vol.100 (21), p.1500-1510

Hollingshead, Melinda G.

2008

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A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept

PloS one, 2013-02, Vol.8 (2), p.e57099

2013

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Enhancement of In vitro and In vivo Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine

Clinical cancer research, 2005-06, Vol.11 (12), p.4571-4579

2005

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Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas

Cancer research (Chicago, Ill.), 2020-01, Vol.80 (2), p.304-318

2020

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ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12), p.2219-2225

2022

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Enhanced Tumor Cell Radiosensitivity and Abrogation of G2 and S Phase Arrest by the Hsp90 Inhibitor 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin

Clinical cancer research, 2004-12, Vol.10 (23), p.8077-8084

2004

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Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers

Clinical cancer research, 2019-05, Vol.25 (10), p.3084-3095

2019

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Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

Molecular cancer, 2008-04, Vol.7 (1), p.29-29, Article 29

2008

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Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis

Journal of pharmaceutical and biomedical analysis, 2021-09, Vol.203, p.114185-114185, Article 114185

2021

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A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo

Free radical biology & medicine, 2011-01, Vol.50 (1), p.110-121

2011

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Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC

International journal of cancer, 2010-12, Vol.127 (11), p.2510-2519

2010

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Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells

Molecular cancer therapeutics, 2006-06, Vol.5 (6), p.1504-1510

2006

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ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC

BMC cancer, 2009-02, Vol.9 (1), p.63-63, Article 63

2009

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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Molecular cancer therapeutics, 2021-04, Vol.20 (4), p.625-631

2021

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In vitro and In vivo Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone)

Clinical cancer research, 2006-05, Vol.12 (9), p.2912-2918

2006

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Specific RITA Modification Produces Hyperselective Cytotoxicity While Maintaining In Vivo Antitumor Efficacy

Molecular cancer therapeutics, 2019-10, Vol.18 (10), p.1765-1774

2019

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Correction: Identification of CBX3 and ABCA5 as Putative Biomarkers for Tumor Stem Cells in Osteosarcoma

PloS one, 2012-11, Vol.7 (11)

2012

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DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors

3'-[18F]fluoro-3'-deoxythymidine ([18F]FLT) Positron Emission Tomography as an In Vivo Biomarker of inhibition of CDK 4/6-Rb pathway by Palbociclib in a patient derived bladder tumor

Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma

Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells

A spontaneously metastatic model of bladder cancer: imaging characterization

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts

Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity

Antitumor Efficacy Testing in Rodents

A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept

Enhancement of In vitro and In vivo Tumor Cell Radiosensitivity by the DNA Methylation Inhibitor Zebularine

Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas

ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

Enhanced Tumor Cell Radiosensitivity and Abrogation of G2 and S Phase Arrest by the Hsp90 Inhibitor 17-(Dimethylaminoethylamino)-17-demethoxygeldanamycin

Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

Development and validation of an LC–MS/MS generic assay platform for small molecule drug bioanalysis

A copper chelate of thiosemicarbazone NSC 689534 induces oxidative/ER stress and inhibits tumor growth in vitro and in vivo

Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC

Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells

ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC

F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

In vitro and In vivo Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone)

Specific RITA Modification Produces Hyperselective Cytotoxicity While Maintaining In Vivo Antitumor Efficacy

Correction: Identification of CBX3 and ABCA5 as Putative Biomarkers for Tumor Stem Cells in Osteosarcoma

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