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Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

Cancer cell, 2008-05, Vol.13 (5), p.454-463

2008

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2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK)

Bioorganic & medicinal chemistry letters, 2003-09, Vol.13 (18), p.3083-3086

2003

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Characterization, chemical optimization and anti-tumor activity of a tubulin poison identified by a p53-based phenotypic screen

Cell cycle (Georgetown, Tex.), 2008-11, Vol.7 (21), p.3417-3427

2008

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Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (5), p.1779-1793

2012

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The discovery of nongenotoxic activators of p53: Building on a cell-based high-throughput screen

Seminars in cancer biology, 2010-02, Vol.20 (1), p.40-45

2010

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Pilot screening programme for small molecule activators of p53

International journal of cancer, 2005-07, Vol.115 (5), p.701-710

2005

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Abstract B25: “TargetDBR”—A DNA repair drug and target discovery collaboration: Exploiting synthetic lethal, high content, and functional cellular reporter assays to accelerate DNA repair targeted drug discovery

Molecular cancer research, 2017-04, Vol.15 (4_Supplement), p.B25-B25

2017

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Synthesis and biological evaluation of functionalised tetrahydro-β-carboline analogues as inhibitors of Toxoplasma gondii invasion

Organic & biomolecular chemistry, 2009, Vol.7 (15), p.3049

2009

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Abstract 4435: Discovery, biological characterization and oral antitumor activity of polo-like kinase 1 (Plk1) selective small molecule inhibitors

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4435-4435

2010

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2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-dependent protein kinase (DNA-PK): Recent advances in the design of kinase inhibitors as novel therapeutic agents

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (18), p.3083-3086

2003

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2,6-Disubstituted Pyran-4-one and Thiopyran-4-one Inhibitors of DNA-Dependent Protein Kinase (DNA-PK)

ChemInform, 2003-12, Vol.34 (51), p.no-no

2003

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Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection

Clinical infectious diseases, 2013-11, Vol.57 (9), p.1304-1307

2013

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P105 Mode of hospital rheumatology appointments in people with rheumatoid arthritis: the impact of the pandemic in England

Rheumatology (Oxford, England), 2023-04, Vol.62 (Supplement_2)

2023

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Health care-associated invasive MRSA infections, 2005-2008

JAMA : the journal of the American Medical Association, 2010-08, Vol.304 (6), p.641

2010

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Feasibility, acceptability and change in health following a telephone-based cognitive behaviour therapy intervention for patients with axial spondyloarthritis

Rheumatology advances in practice, 2021-01, Vol.5 (2), p.rkaa063-rkaa063

2021

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Feasibility, acceptability and change in health following a telephone-based cognitive behaviour therapy intervention for patients with axial spondylarthritis

Rheumatology advances in practice, 2021-07, Vol.5 (2)

2021

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Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK)

Characterization, chemical optimization and anti-tumor activity of a tubulin poison identified by a p53-based phenotypic screen

Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins

Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol 3-Kinase Related Kinases. Structure−Activity Relationships for DNA-Dependent Protein Kinase Inhibition, and Identification of the First Potent and Selective Inhibitor of the Ataxia Telangiectasia Mutated Kinase

The discovery of nongenotoxic activators of p53: Building on a cell-based high-throughput screen

Pilot screening programme for small molecule activators of p53

Abstract B25: “TargetDBR”—A DNA repair drug and target discovery collaboration: Exploiting synthetic lethal, high content, and functional cellular reporter assays to accelerate DNA repair targeted drug discovery

Synthesis and biological evaluation of functionalised tetrahydro-β-carboline analogues as inhibitors of Toxoplasma gondii invasion

Abstract 4435: Discovery, biological characterization and oral antitumor activity of polo-like kinase 1 (Plk1) selective small molecule inhibitors

2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-dependent protein kinase (DNA-PK): Recent advances in the design of kinase inhibitors as novel therapeutic agents

2,6-Disubstituted Pyran-4-one and Thiopyran-4-one Inhibitors of DNA-Dependent Protein Kinase (DNA-PK)

Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection

P105 Mode of hospital rheumatology appointments in people with rheumatoid arthritis: the impact of the pandemic in England

Health care-associated invasive MRSA infections, 2005-2008

Feasibility, acceptability and change in health following a telephone-based cognitive behaviour therapy intervention for patients with axial spondyloarthritis

Feasibility, acceptability and change in health following a telephone-based cognitive behaviour therapy intervention for patients with axial spondylarthritis

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