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Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities

Nature reviews. Cancer, 2022-07, Vol.22 (7), p.414-430

2022

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Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

PLoS genetics, 2018-01, Vol.14 (1), p.e1007135-e1007135

2018

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Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation

Molecular cell, 2015-01, Vol.57 (1), p.95-107

2015

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A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

Breast cancer research : BCR, 2014-01, Vol.16 (3), p.R59-R59

2014

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B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

Cell, 2019-11, Vol.179 (5), p.1191-1206.e21

2019

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The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

Molecular and cellular biology, 2014-09, Vol.34 (17), p.3229-3243

2014

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The Evolving Landscape of B Cells in Cancer Metastasis

Cancer research (Chicago, Ill.), 2023-12, Vol.83 (23), p.3835-3845

2023

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E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

Scientific reports, 2019-07, Vol.9 (1), p.10718-13, Article 10718

2019

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Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

PLoS genetics, 2022-09, Vol.18 (9), p.e1010362-e1010362

2022

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Memory B cell fitness and anergy has significant links to cancer lethality

Cell, 2024-08, Vol.187 (17), p.4551-4553

Hollern, Daniel

2024

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FOXA1 overexpression suppresses interferon signaling and immune response in cancer

The Journal of clinical investigation, 2021-07, Vol.131 (14)

2021

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Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs

Molecular cancer therapeutics, 2022-04, Vol.21 (4), p.616-624

2022

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PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

Breast cancer research : BCR, 2021-01, Vol.23 (1), p.10-10, Article 10

2021

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FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease

The Journal of clinical investigation, 2020-09, Vol.130 (9), p.4871-4887

2020

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Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

Breast cancer research : BCR, 2021-08, Vol.23 (1), p.81-81, Article 81

2021

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Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

Cell reports (Cambridge), 2018-10, Vol.25 (3), p.702-714.e6

2018

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Prediction and Genetic Demonstration of a Role for Activator E2Fs in Myc-Induced Tumors

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (5), p.1924-1932

2011

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Virus expression detection reveals RNA-sequencing contamination in TCGA

BMC genomics, 2020-01, Vol.21 (1), p.79-79, Article 79

2020

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Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway

Cell death & disease, 2022-03, Vol.13 (3), p.195-195, Article 195

2022

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Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

Genome medicine, 2018-11, Vol.10 (1), p.86-86, Article 86

2018

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A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

Breast cancer research and treatment, 2019-02, Vol.174 (1), p.143-155

2019

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DAB2IP Loss in Luminal A Breast Cancer Leads to NF-kB Associated Aggressive Oncogenic Phenotypes

JCI insight, 2024-10

2024

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A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis

Frontiers in cell and developmental biology, 2018-07, Vol.6, p.69-69

2018

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B cells secrete GABA, which provokes a pro-tumor immune microenvironment

Cancer cell, 2022-01, Vol.40 (1), p.17-19

2022

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Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities

Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation

A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer

B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

The E2F Transcription Factors Regulate Tumor Development and Metastasis in a Mouse Model of Metastatic Breast Cancer

The Evolving Landscape of B Cells in Cancer Metastasis

E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH

Memory B cell fitness and anergy has significant links to cancer lethality

FOXA1 overexpression suppresses interferon signaling and immune response in cancer

Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs

PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease

Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and αPD-1 Enable Sustained Antitumor Responses against Established HER2 Breast Cancer

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

Prediction and Genetic Demonstration of a Role for Activator E2Fs in Myc-Induced Tumors

Virus expression detection reveals RNA-sequencing contamination in TCGA

Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway

Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer

A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer

DAB2IP Loss in Luminal A Breast Cancer Leads to NF-kB Associated Aggressive Oncogenic Phenotypes

A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis

B cells secrete GABA, which provokes a pro-tumor immune microenvironment

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