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Epidermal sphingolipids: Metabolism, function, and roles in skin disorders

FEBS letters, 2006-10, Vol.580 (23), p.5456-5466

2006

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Formation and functions of the corneocyte lipid envelope (CLE)

Biochimica et biophysica acta, 2014-03, Vol.1841 (3), p.314-318

2014

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Regulation of Cathelicidin Antimicrobial Peptide Expression by an Endoplasmic Reticulum (ER) Stress Signaling, Vitamin D Receptor-independent Pathway

The Journal of biological chemistry, 2011-09, Vol.286 (39), p.34121-34130

2011

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Omega- O -acylceramide, a lipid essential for mammalian survival

Journal of dermatological science, 2008-08, Vol.51 (2), p.77-87

2008

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ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (10), p.E1334-E1342

2016

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Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

PloS one, 2016-08, Vol.11 (8), p.e0161465-e0161465

2016

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Increased glucocorticoid activation during mouse skin wound healing

Journal of endocrinology, 2014-04, Vol.221 (1), p.51-61

2014

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Imaging mass spectrometry visualizes ceramides and the pathogenesis of dorfman-chanarin syndrome due to ceramide metabolic abnormality in the skin

PloS one, 2012-11, Vol.7 (11), p.e49519-e49519

2012

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A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

Molecular and Cellular Biology, 2013-02, Vol.33 (4), p.752-762

2013

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Maintenance of an Acidic Stratum Corneum Prevents Emergence of Murine Atopic Dermatitis

Journal of investigative dermatology, 2009-07, Vol.129 (7), p.1824-1835

2009

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Altered sphingoid base profiles predict compromised membrane structure and permeability in atopic dermatitis

Journal of dermatological science, 2013-12, Vol.72 (3), p.296-303

2013

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Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction

Journal of dermatological science, 2013-10, Vol.72 (1), p.32-44

2013

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Murine atopic dermatitis responds to peroxisome proliferator-activated receptors α and β/δ (but not γ) and liver X receptor activators

Journal of allergy and clinical immunology, 2010, Vol.125 (1), p.160-169.e5

2010

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Neutral Lipid Storage Leads to Acylceramide Deficiency, Likely Contributing to the Pathogenesis of Dorfman–Chanarin Syndrome

Journal of investigative dermatology, 2010-10, Vol.130 (10), p.2497-2499

2010

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Basis for Improved Permeability Barrier Homeostasis Induced by PPAR and LXR Activators: Liposensors Stimulate Lipid Synthesis, Lamellar Body Secretion, and Post-Secretory Lipid Processing

Journal of investigative dermatology, 2006-02, Vol.126 (2), p.386-392

2006

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Hydrolytic Pathway Protects against Ceramide-Induced Apoptosis in Keratinocytes Exposed to UVB

Journal of investigative dermatology, 2010-10, Vol.130 (10), p.2472-2480

2010

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On the effects of topical synthetic pseudoceramides: Comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides

Journal of dermatological science, 2008-07, Vol.51 (1), p.37-43

2008

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Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

Journal of lipid research, 2000-12, Vol.41 (12), p.2071-2082

2000

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Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation

The Journal of biological chemistry, 2008-06, Vol.283 (24), p.16682-16692

2008

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Fatty Acid 2-Hydroxylase, Encoded by FA2H, Accounts for Differentiation-associated Increase in 2-OH Ceramides during Keratinocyte Differentiation

The Journal of biological chemistry, 2007-05, Vol.282 (18), p.13211-13219

2007

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Infection and inflammation induce LDL oxidation in vivo

Arteriosclerosis, thrombosis, and vascular biology, 2000-06, Vol.20 (6), p.1536-1542

2000

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Topical 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Corrects Cutaneous Features of Systemic Glucocorticoid Excess in Female Mice

Endocrinology (Philadelphia), 2018-01, Vol.159 (1), p.547-556

2018

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Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells

Cancer research (Chicago, Ill.), 2004-09, Vol.64 (17), p.6271-6279

2004

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Sphingosine-1-Phosphate–Cathelicidin Axis Plays a Pivotal Role in the Development of Cutaneous Squamous Cell Carcinoma

Journal of investigative dermatology, 2024-08

2024

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Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism

Journal of lipid research, 2008-04, Vol.49 (4), p.697-714

2008

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Epidermal sphingolipids: Metabolism, function, and roles in skin disorders

Formation and functions of the corneocyte lipid envelope (CLE)

Regulation of Cathelicidin Antimicrobial Peptide Expression by an Endoplasmic Reticulum (ER) Stress Signaling, Vitamin D Receptor-independent Pathway

Omega- O -acylceramide, a lipid essential for mammalian survival

ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

Increased glucocorticoid activation during mouse skin wound healing

Imaging mass spectrometry visualizes ceramides and the pathogenesis of dorfman-chanarin syndrome due to ceramide metabolic abnormality in the skin

A Novel Role of a Lipid Species, Sphingosine-1-Phosphate, in Epithelial Innate Immunity

Maintenance of an Acidic Stratum Corneum Prevents Emergence of Murine Atopic Dermatitis

Altered sphingoid base profiles predict compromised membrane structure and permeability in atopic dermatitis

Selective matrix (hyaluronan) interaction with CD44 and RhoGTPase signaling promotes keratinocyte functions and overcomes age-related epidermal dysfunction

Murine atopic dermatitis responds to peroxisome proliferator-activated receptors α and β/δ (but not γ) and liver X receptor activators

Neutral Lipid Storage Leads to Acylceramide Deficiency, Likely Contributing to the Pathogenesis of Dorfman–Chanarin Syndrome

Basis for Improved Permeability Barrier Homeostasis Induced by PPAR and LXR Activators: Liposensors Stimulate Lipid Synthesis, Lamellar Body Secretion, and Post-Secretory Lipid Processing

Hydrolytic Pathway Protects against Ceramide-Induced Apoptosis in Keratinocytes Exposed to UVB

On the effects of topical synthetic pseudoceramides: Comparison of possible keratinocyte toxicities provoked by the pseudoceramides, PC104 and BIO391, and natural ceramides

Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

Decreased Ceramide Transport Protein (CERT) Function Alters Sphingomyelin Production following UVB Irradiation

Fatty Acid 2-Hydroxylase, Encoded by FA2H, Accounts for Differentiation-associated Increase in 2-OH Ceramides during Keratinocyte Differentiation

Infection and inflammation induce LDL oxidation in vivo

Topical 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Corrects Cutaneous Features of Systemic Glucocorticoid Excess in Female Mice

Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells

Sphingosine-1-Phosphate–Cathelicidin Axis Plays a Pivotal Role in the Development of Cutaneous Squamous Cell Carcinoma

Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism

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