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CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

PLoS pathogens, 2019-05, Vol.15 (5), p.e1007748-e1007748

2019

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Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function

Nature communications, 2019-10, Vol.10 (1), p.4451-15, Article 4451

2019

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Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function

Frontiers in immunology, 2024-05, Vol.15, p.1386132

2024

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Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (45), p.19078-19083

2009

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Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells

Oncoimmunology, 2019-03, Vol.8 (3), p.1542917-1542917

2019

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CD3 limits the efficacy of TCR gene therapy in vivo

Blood, 2011-09, Vol.118 (13), p.3528-3537

2011

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Engineering CD4+ T Cells to Enhance Cancer Immunity

Cells (Basel, Switzerland), 2020-07, Vol.9 (7), p.1721

2020

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Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing

Cellular & molecular immunology, 2020-12, Vol.17 (12), p.1275-1277

2020

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Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy

Haematologica (Roma), 2016-04, Vol.101 (4), p.482-490

2016

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Forced Fox-P3 expression can improve the safety and antigen-specific function of engineered regulatory T cells

Journal of autoimmunity, 2022-10, Vol.132, p.102888-102888, Article 102888

2022

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Detection of Wilms' Tumor Antigen–Specific CTL in Tumor-Draining Lymph Nodes of Patients with Early Breast Cancer

Clinical cancer research, 2006-01, Vol.12 (1), p.34-42

2006

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CD27 is required for protective lytic EBV antigen–specific CD8+ T-cell expansion

Blood, 2021-06, Vol.137 (23), p.3225-3236

2021

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Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma

Molecular therapy, 2018-06, Vol.26 (6), p.1471-1481

2018

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A study of T cell tolerance to the tumor-associated antigen MDM2: cytokines can restore antigen responsiveness, but not high avidity T cell function

PloS one, 2007-04, Vol.2 (4), p.e353-e353

2007

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Retroviral transfer for a chimeric antigen receptor to generate regulatory T-like cells for the suppression of undesired immune responses. (VAC7P.1036)

The Journal of immunology (1950), 2015-05, Vol.194 (1_Supplement), p.143-143.6

2015

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Redirection to the bone marrow improves T cell persistence and antitumor functions

The Journal of clinical investigation, 2018-05, Vol.128 (5), p.2010-2024

2018

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Genetic Regulation of Fate Decisions in Therapeutic T Cells to Enhance Tumor Protection and Memory Formation

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (13), p.2641-2652

2015

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CD8.sup.+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

PLoS pathogens, 2019-05, Vol.15 (5)

2019

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CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor

The Journal of immunology (1950), 2015-02, Vol.194 (3), p.1080-1089

2015

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Barrieren der Weiterbildung aelterer Arbeitnehmer-innen: Studie mit Literaturteil und Forschungsbericht

1995

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Human MHC Class I-restricted high avidity CD4+ T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo

Oncoimmunology, 2013-01, Vol.2 (1), p.e22590-e22590

2013

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T Cells Engineered For Resistance To Mycophenolate Mofetil Demonstrate Enhanced Expansion and Improved Tumour Control In Immunosuppressed Hosts

Blood, 2013-11, Vol.122 (21), p.4486-4486

2013

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Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination

Blood, 2011-06, Vol.117 (25), p.6813-6824

2011

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CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

Blood, 2012-11, Vol.120 (21), p.952-952

2012

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CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function

Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells

CD3 limits the efficacy of TCR gene therapy in vivo

Engineering CD4+ T Cells to Enhance Cancer Immunity

Enhancing the expression and function of an EBV-TCR on engineered T cells by combining Sc-TCR design with CRISPR editing to prevent mispairing

Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy

Forced Fox-P3 expression can improve the safety and antigen-specific function of engineered regulatory T cells

Detection of Wilms' Tumor Antigen–Specific CTL in Tumor-Draining Lymph Nodes of Patients with Early Breast Cancer

CD27 is required for protective lytic EBV antigen–specific CD8+ T-cell expansion

Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma

A study of T cell tolerance to the tumor-associated antigen MDM2: cytokines can restore antigen responsiveness, but not high avidity T cell function

Retroviral transfer for a chimeric antigen receptor to generate regulatory T-like cells for the suppression of undesired immune responses. (VAC7P.1036)

Redirection to the bone marrow improves T cell persistence and antitumor functions

Genetic Regulation of Fate Decisions in Therapeutic T Cells to Enhance Tumor Protection and Memory Formation

CD8.sup.+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo

A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation

CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor

Barrieren der Weiterbildung aelterer Arbeitnehmer-innen: Studie mit Literaturteil und Forschungsbericht

Human MHC Class I-restricted high avidity CD4+ T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo

T Cells Engineered For Resistance To Mycophenolate Mofetil Demonstrate Enhanced Expansion and Improved Tumour Control In Immunosuppressed Hosts

Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination

CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens

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