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Long‐term effects of adjunctive eslicarbazepine acetate in adult Asian patients with refractory focal seizures: Post hoc analysis of a phase III trial

Clinical and translational science, 2024-05, Vol.17 (5), p.e13802-n/a

2024

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Advances in Lead Generation

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (4), p.517-524

2019

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Metabolism and disposition of zamicastat in rats

Xenobiotica, 2024-10, p.1-12

2024

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Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson’s disease: pooled analysis of patient level data from two randomized open-label studies

Journal of neurology, 2024-10, Vol.271 (10), p.6729-6738

2024

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Biomolecular Simulations in Structure-Based Drug Discovery

1, 2019

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Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands. 1. N-Substituted Spiro[piperidine-4,4′-thieno[3,2-c]pyrans]

Journal of medicinal chemistry, 2008-10, Vol.51 (20), p.6531-6537

2008

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Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction

Bioorganic & medicinal chemistry letters, 2018-12, Vol.28 (23-24), p.3793-3797

2018

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Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands: Relationships between Substitution Pattern and σ Receptor Affinity

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5350-5360

2012

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The hydroxycarboxylic acid receptor HCA2 is required for the protective effect of ketogenic diet in epilepsy

Pharmacology research & perspectives, 2024-12, Vol.12 (6), p.e70026

2024

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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

1, 2018

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Chronic 5‐HT6 receptor modulation by E‐6837 induces hypophagia and sustained weight loss in diet‐induced obese rats

British journal of pharmacology, 2006-08, Vol.148 (7), p.973-983

2006

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Comprehensive Medicinal Chemistry III

3, 2017

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Synthesis of 3-(2-N,N-diethylaminoethoxy)indoles as potential 5-HT6 receptor ligands

Organic & biomolecular chemistry, 2008-05, Vol.6 (10), p.1802-1807

2008

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Synthesis of σ receptor ligands with unsymmetrical spiro connection of the piperidine moiety

European journal of medicinal chemistry, 2009-11, Vol.44 (11), p.4306-4314

2009

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Indene-based frameworks targeting the 5-HT6 serotonin receptor: Ring constraint in indenylsulfonamides using cyclic amines and structurally abbreviated counterparts

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7387-7397

2009

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Identification of Novel Indanylsulfonamide Guanylhydrazones as Potent 5-HT6 Serotonin Receptor Antagonists

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.6153-6157

2009

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Novel K V 7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction

Bioorganic & medicinal chemistry letters, 2018-12, Vol.28 (23-24), p.3793

2018

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Indene-based frameworks targeting the 5-HT sub(6) serotonin receptor: Ring constraint in indenylsulfonamides using cyclic amines and structurally abbreviated counterparts

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7387-7397

2009

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Targeted Drug Delivery

1, 2022

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An Introduction to Volume 8: Case Histories in Recent Drug Discovery

Comprehensive Medicinal Chemistry III, 2017, p.xv-xv

Third Edition, 2017

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Novel derivatives of 3-alkyl-1,5-diaryl-1H-1,2,4-triazoles and their pharmacological evaluation as CB1 cannabinoid ligands

Monatshefte für Chemie, 2008-09, Vol.139 (9), p.1073-1082

2008

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A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands

ChemMedChem, 2006-01, Vol.1 (1), p.140-154

2006

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ChemInform Abstract: Novel Derivatives of 3‐Alkyl‐1,5‐diaryl‐1H‐1,2,4‐triazoles and Their Pharmacological Evaluation as CB 1 Cannabinoid Ligands

ChemInform, 2008-12, Vol.39 (51)

2008

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ChemInform Abstract: Novel Derivatives of 3-Alkyl-1,5-diaryl-1H-1,2,4-triazoles and Their Pharmacological Evaluation as CB1 Cannabinoid Ligands

ChemInform, 2008-12, Vol.39 (51), p.no-no

2008

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ChemInform Abstract: Synthesis of 3‐(2‐N,N‐Diethylaminoethoxy)indoles as Potential 5‐HT 6 Receptor Ligands

ChemInform, 2008-09, Vol.39 (37)

2008

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Long‐term effects of adjunctive eslicarbazepine acetate in adult Asian patients with refractory focal seizures: Post hoc analysis of a phase III trial

Advances in Lead Generation

Metabolism and disposition of zamicastat in rats

Opicapone for the treatment of early wearing-off in levodopa-treated Parkinson’s disease: pooled analysis of patient level data from two randomized open-label studies

Biomolecular Simulations in Structure-Based Drug Discovery

Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands. 1. N-Substituted Spiro[piperidine-4,4′-thieno[3,2-c]pyrans]

Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction

Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands: Relationships between Substitution Pattern and σ Receptor Affinity

The hydroxycarboxylic acid receptor HCA2 is required for the protective effect of ketogenic diet in epilepsy

Drug Selectivity: An Evolving Concept in Medicinal Chemistry

Chronic 5‐HT6 receptor modulation by E‐6837 induces hypophagia and sustained weight loss in diet‐induced obese rats

Comprehensive Medicinal Chemistry III

Synthesis of 3-(2-N,N-diethylaminoethoxy)indoles as potential 5-HT6 receptor ligands

Synthesis of σ receptor ligands with unsymmetrical spiro connection of the piperidine moiety

Indene-based frameworks targeting the 5-HT6 serotonin receptor: Ring constraint in indenylsulfonamides using cyclic amines and structurally abbreviated counterparts

Identification of Novel Indanylsulfonamide Guanylhydrazones as Potent 5-HT6 Serotonin Receptor Antagonists

Novel K V 7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction

Indene-based frameworks targeting the 5-HT sub(6) serotonin receptor: Ring constraint in indenylsulfonamides using cyclic amines and structurally abbreviated counterparts

Targeted Drug Delivery

An Introduction to Volume 8: Case Histories in Recent Drug Discovery

Novel derivatives of 3-alkyl-1,5-diaryl-1H-1,2,4-triazoles and their pharmacological evaluation as CB1 cannabinoid ligands

A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands

ChemInform Abstract: Novel Derivatives of 3‐Alkyl‐1,5‐diaryl‐1H‐1,2,4‐triazoles and Their Pharmacological Evaluation as CB 1 Cannabinoid Ligands

ChemInform Abstract: Novel Derivatives of 3-Alkyl-1,5-diaryl-1H-1,2,4-triazoles and Their Pharmacological Evaluation as CB1 Cannabinoid Ligands

ChemInform Abstract: Synthesis of 3‐(2‐N,N‐Diethylaminoethoxy)indoles as Potential 5‐HT 6 Receptor Ligands

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