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Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis

PloS one, 2011-04, Vol.6 (4), p.e18517

2011

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Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells

PloS one, 2020, Vol.15 (3), p.e0224344-e0224344

2020

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Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

PloS one, 2017-02, Vol.12 (2), p.e0172567-e0172567

2017

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Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.5242-5247

2014

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A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

Cell metabolism, 2012-07, Vol.16 (1), p.33-43

2012

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Pdx-1 Activates Islet α- and β-Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

Molecular and Cellular Biology, 2013-10, Vol.33 (20), p.4017-4029

2013

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A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation

Molecular and cellular biology, 2016-12, Vol.36 (23), p.2918-2930

2016

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Efficient Gene Delivery to Pancreatic Islets with Ultrasonic Microbubble Destruction Technology

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (22), p.8469-8474

2006

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The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets

The Journal of pharmacology and experimental therapeutics, 2013-02, Vol.344 (2), p.407-416

2013

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Stimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

Molecular and Cellular Biology, 2008-05, Vol.28 (10), p.3465-3476

2008

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Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion

The Journal of biological chemistry, 2013-08, Vol.288 (32), p.23128-23140

2013

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Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets

The Journal of biological chemistry, 2008-10, Vol.283 (43), p.28909-28917

2008

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Pro- and Antiapoptotic Proteins Regulate Apoptosis but Do Not Protect Against Cytokine-Mediated Cytotoxicity in Rat Islets and β-Cell Lines

Diabetes (New York, N.Y.), 2006-05, Vol.55 (5), p.1398-1406

2006

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Improving human β-cell maturation in vitro

Nature cell biology, 2019-02, Vol.21 (2), p.119-121

2019

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Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

Diabetes (New York, N.Y.), 2000-03, Vol.49 (3), p.424-430

2000

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Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells

Molecular endocrinology (Baltimore, Md.), 2015-09, Vol.29 (9), p.1243-1253

2015

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Discrete and Complementary Mechanisms of Protection of β-Cells Against Cytokine-Induced and Oxidative Damage Achieved by bcl-2 Overexpression and a Cytokine Selection Strategy

Diabetes (New York, N.Y.), 2003-06, Vol.52 (6), p.1423-1432

2003

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Cell lines derived from pancreatic islets

Molecular and cellular endocrinology, 2004-12, Vol.228 (1), p.121-128

2004

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Agenesis of the Dorsal Pancreas and Associated Diseases

Digestive diseases and sciences, 2009-03, Vol.54 (3), p.481-487

2009

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Regulation of insulin secretion from novel engineered insulinoma cell lines

Diabetes (New York, N.Y.), 1997-06, Vol.46 (6), p.968-977

1997

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Cholinergic augmentation of insulin release requires ankyrin-B

Science signaling, 2010-03, Vol.3 (113), p.ra19

2010

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Trefoil Factor 3 Stimulates Human and Rodent Pancreatic Islet β-Cell Replication with Retention of Function

Molecular endocrinology (Baltimore, Md.), 2008-05, Vol.22 (5), p.1251-1259

2008

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Functional Genomics of the β-Cell: Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Regulates Insulin Secretion Independent of K+ Currents

Molecular endocrinology (Baltimore, Md.), 2007-03, Vol.21 (3), p.765-773

2007

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Increased Insulin Sensitivity in Mice Lacking Collectrin, a Downstream Target of HNF-1α

Molecular endocrinology (Baltimore, Md.), 2009-06, Vol.23 (6), p.881-892

2009

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Islets for all?

Nature biotechnology, 2005-10, Vol.23 (10), p.1231-1232

2005

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Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis

Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

Pdx-1 Activates Islet α- and β-Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation

Efficient Gene Delivery to Pancreatic Islets with Ultrasonic Microbubble Destruction Technology

The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets

Stimulation of Human and Rat Islet β-Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion

Silencing of Cytosolic or Mitochondrial Isoforms of Malic Enzyme Has No Effect on Glucose-stimulated Insulin Secretion from Rodent Islets

Pro- and Antiapoptotic Proteins Regulate Apoptosis but Do Not Protect Against Cytokine-Mediated Cytotoxicity in Rat Islets and β-Cell Lines

Improving human β-cell maturation in vitro

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells

Discrete and Complementary Mechanisms of Protection of β-Cells Against Cytokine-Induced and Oxidative Damage Achieved by bcl-2 Overexpression and a Cytokine Selection Strategy

Cell lines derived from pancreatic islets

Agenesis of the Dorsal Pancreas and Associated Diseases

Regulation of insulin secretion from novel engineered insulinoma cell lines

Cholinergic augmentation of insulin release requires ankyrin-B

Trefoil Factor 3 Stimulates Human and Rodent Pancreatic Islet β-Cell Replication with Retention of Function

Functional Genomics of the β-Cell: Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Regulates Insulin Secretion Independent of K+ Currents

Increased Insulin Sensitivity in Mice Lacking Collectrin, a Downstream Target of HNF-1α

Islets for all?

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