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Allosteric inhibitors of Akt1 and Akt2: A naphthyridinone with efficacy in an A2780 tumor xenograft model

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3178-3182

2008

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Update: Causes and symptoms of sudden cardiac death in young athletes

The Physician and sportsmedicine, 2015-02, Vol.43 (1), p.44-53

2015

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2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2922-2925

1991

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Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

Journal of medicinal chemistry, 1992-10, Vol.35 (21), p.3792-3802

1992

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Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogs

Journal of medicinal chemistry, 1993-04, Vol.36 (8), p.953-966

1993

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Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogs

Journal of medicinal chemistry, 1992-10, Vol.35 (21), p.3784-3791

1992

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Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one

Journal of medicinal chemistry, 1993, Vol.36 (2), p.249-255

1993

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Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides

Journal of medicinal chemistry, 1990-02, Vol.33 (2), p.749-754

1990

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Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

Journal of Virology, 1991-09, Vol.65 (9), p.4887-4892

1991

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Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives

Journal of medicinal chemistry, 1983-04, Vol.26 (4), p.538-544

1983

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Pyridinone Derivatives: Specific Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors with Antiviral Activity

Proceedings of the National Academy of Sciences - PNAS, 1991-08, Vol.88 (15), p.6863-6867

1991

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A practical synthesis of 5-(chloromethyl)furo[2,3-b]pyridine, a key intermediate for the HIV protease inhibitor, L-754,394

Journal of heterocyclic chemistry, 1995-07, Vol.32 (4), p.1283-1287

1995

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Allosteric inhibitors of Aktl and Akt2 : A naphthyridinone with efficacy in an A2780 tumor xenograft model

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (11), p.3178-3182

2008

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Antiaromaticity in the parent cyclopentadienyl cation. Reaction of 5-iodocyclopentadiene with silver ion

Journal of the American Chemical Society, 1972-03, Vol.94 (6), p.2110-2111

1972

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Identification of MK-944a: A Second Clinical Candidate from the Hydroxylaminepentanamide Isostere Series of HIV Protease Inhibitors

Journal of medicinal chemistry, 2000-09, Vol.43 (18), p.3386-3399

2000

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Synthesis of 3-nitro-5-acylpyridines by condensation of sodium nitromalonaldehyde/tosyl chloride with 2-amino-1-acylolefins. Evidence for the intermediacy of 3-chloro-2-nitroacrolein

Journal of organic chemistry, 1984-01, Vol.49 (1), p.193-195

1984

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Solvolytic Cope rearrangements

Journal of the American Chemical Society, 1972-03, Vol.94 (6), p.2111-2112

1972

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A deuterium isotope effect on the inhibition of gastric secretion by N,N-dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(4,6-dimethyl-2-pyridyl)urea. Synthesis of metabolites

Journal of medicinal chemistry, 1983-11, Vol.26 (11), p.1650-1653

1983

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Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogs related to cimetidine and tiotidine

Journal of medicinal chemistry, 1983-02, Vol.26 (2), p.140-144

1983

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Structure-activity, theoretical, and x-ray studies on the intramolecular interactions in a series of novel histamine H2 receptor antagonists

Journal of medicinal chemistry, 1984-08, Vol.27 (8), p.1047-1052

1984

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Inhibition of gastric acid secretion by 1,8-naphthyridin-2(1H)-ones

Journal of medicinal chemistry, 1979-03, Vol.22 (3), p.301-306

1979

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Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity

Journal of medicinal chemistry, 1989-12, Vol.32 (12), p.2548-2554

1989

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Attempted prophylaxis of human immunodeficiency virus type 1 infection in chimpanzees with a nonnucleoside reverse transcriptase inhibitor

AIDS research and human retroviruses, 1994, Vol.10 (1), p.107-110

1994

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Synthesis of 3-nitro-5-acylpyridines by condensation of sodium nitromalonaldehyde/tosyl chloride with 2-amino-1-acyl olefins. Evidence for the intermediacy of 3-chloro-2-nitroacrolein

Journal of organic chemistry, 1984, Vol.49 (1), p.193-195

1984

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Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2 receptor antagonists

Journal of medicinal chemistry, 1982-03, Vol.25 (3), p.207-210

1982

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Allosteric inhibitors of Akt1 and Akt2: A naphthyridinone with efficacy in an A2780 tumor xenograft model

Update: Causes and symptoms of sudden cardiac death in young athletes

2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogs

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogs

Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one

Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides

Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors

Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives

Pyridinone Derivatives: Specific Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors with Antiviral Activity

A practical synthesis of 5-(chloromethyl)furo[2,3-b]pyridine, a key intermediate for the HIV protease inhibitor, L-754,394

Allosteric inhibitors of Aktl and Akt2 : A naphthyridinone with efficacy in an A2780 tumor xenograft model

Antiaromaticity in the parent cyclopentadienyl cation. Reaction of 5-iodocyclopentadiene with silver ion

Identification of MK-944a: A Second Clinical Candidate from the Hydroxylaminepentanamide Isostere Series of HIV Protease Inhibitors

Synthesis of 3-nitro-5-acylpyridines by condensation of sodium nitromalonaldehyde/tosyl chloride with 2-amino-1-acylolefins. Evidence for the intermediacy of 3-chloro-2-nitroacrolein

Solvolytic Cope rearrangements

A deuterium isotope effect on the inhibition of gastric secretion by N,N-dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(4,6-dimethyl-2-pyridyl)urea. Synthesis of metabolites

Conformational requirements for histamine H2-receptor inhibitors: a structure-activity study of phenylene analogs related to cimetidine and tiotidine

Structure-activity, theoretical, and x-ray studies on the intramolecular interactions in a series of novel histamine H2 receptor antagonists

Inhibition of gastric acid secretion by 1,8-naphthyridin-2(1H)-ones

Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity

Attempted prophylaxis of human immunodeficiency virus type 1 infection in chimpanzees with a nonnucleoside reverse transcriptase inhibitor

Synthesis of 3-nitro-5-acylpyridines by condensation of sodium nitromalonaldehyde/tosyl chloride with 2-amino-1-acyl olefins. Evidence for the intermediacy of 3-chloro-2-nitroacrolein

Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2 receptor antagonists

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