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Efficacy of N-acetyl cysteine in traumatic brain injury

PloS one, 2014-04, Vol.9 (4), p.e90617-e90617

2014

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Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP

Scientific reports, 2016-09, Vol.6 (1), p.32656-32656, Article 32656

2016

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Mitochondria: A Therapeutic Target for Parkinson's Disease?

International journal of molecular sciences, 2015-09, Vol.16 (9), p.20704-20730

2015

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Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats

PloS one, 2013-12, Vol.8 (12), p.e82016

2013

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Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study

PloS one, 2013-01, Vol.8 (1), p.e54163

2013

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Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

Journal of neuroinflammation, 2015-03, Vol.12 (1), p.45-45, Article 45

2015

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A New Treatment Strategy for Parkinson's Disease through the Gut–Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway

Cell Transplantation, 2017-09, Vol.26 (9), p.1560-1571

2017

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Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke

PloS one, 2011-08, Vol.6 (8), p.e22135-e22135

2011

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Drug Repurposing in the Treatment of Traumatic Brain Injury

Frontiers in neuroscience, 2021-03, Vol.15, p.635483

2021

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Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)

PloS one, 2016-06, Vol.11 (6), p.e0157064-e0157064

2016

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PT320, a Sustained-Release GLP-1 Receptor Agonist, Ameliorates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson's Disease

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4687

2023

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Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

Nature (London), 2013-09, Vol.501 (7467), p.412-415

2013

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GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (4), p.1285-1290

2009

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High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (46), p.20087-20092

2010

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Pomalidomide Ameliorates H₂O₂-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects

International journal of molecular sciences, 2018-10, Vol.19 (10), p.3252

2018

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(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice

Neurobiology of disease, 2019-10, Vol.130, p.104528-104528, Article 104528

2019

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Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine

Journal of biomedical science, 2017-09, Vol.24 (1), p.71-71, Article 71

2017

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Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6'-Dithiothalidomide on Traumatic Brain Injury

International journal of molecular sciences, 2019-01, Vol.20 (3), p.502

2019

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Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury

Neurobiology of disease, 2019-04, Vol.124, p.439-453

2019

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Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

Alzheimer's & dementia, 2022-11, Vol.18 (11), p.2327-2340

2022

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Maternally transmitted mitochondrial DNA mutations can reduce lifespan

Scientific reports, 2014-10, Vol.4 (1), p.6569-6569, Article 6569

2014

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Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury

eLife, 2020-08, Vol.9

2020

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Impact of Traumatic Brain Injury on Dopaminergic Transmission

Cell transplantation, 2017-07, Vol.26 (7), p.1156-1168

2017

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Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice

Journal of biomedical science, 2024-04, Vol.31 (1), p.38-38

2024

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Efficacy of N-acetyl cysteine in traumatic brain injury

Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP

Mitochondria: A Therapeutic Target for Parkinson's Disease?

Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats

Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study

Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

A New Treatment Strategy for Parkinson's Disease through the Gut–Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway

Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke

Drug Repurposing in the Treatment of Traumatic Brain Injury

Thioredoxin-Mimetic-Peptides Protect Cognitive Function after Mild Traumatic Brain Injury (mTBI)

PT320, a Sustained-Release GLP-1 Receptor Agonist, Ameliorates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson's Disease

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

Pomalidomide Ameliorates H₂O₂-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects

(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice

Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine

Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6'-Dithiothalidomide on Traumatic Brain Injury

Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms

Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury

Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

Maternally transmitted mitochondrial DNA mutations can reduce lifespan

Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury

Impact of Traumatic Brain Injury on Dopaminergic Transmission

Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice

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